Patents by Inventor Ya-Ping Lai

Ya-Ping Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-TIGIT ANTIBODIES AND METHODS OF USE
    Publication number: 20230416362
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Application
    Filed: May 17, 2023
    Publication date: December 28, 2023
    Applicant: Industrial Technology Research Institute
    Inventors: Min-Yuan CHOU, Li-Tsen LIN, Chung-Yuan SUN, Ya-Ping LAI, Chin-Pen LAI, Ssu-Yuan WU, Mei-Wei LIN
  • Anti-TIGIT antibodies and methods of use
    Patent number: 11667709
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: June 6, 2023
    Assignee: Industrial Technology Research Institute
    Inventors: Min-Yuan Chou, Li-Tsen Lin, Chung-Yuan Sun, Ya-Ping Lai, Chin-Pen Lai, Ssu-Yuan Wu, Mei-Wei Lin
  • ANTI-TIGIT ANTIBODIES AND METHODS OF USE
    Publication number: 20210087266
    Abstract: Antibodies and antigen-binding fragments that bind to TIGIT are disclosed. The disclosure further relates to methods and compositions for use in treating an immune-related disease (e.g., a cancer or an infection or infectious disease) by administering a composition disclosed herein.
    Type: Application
    Filed: September 23, 2020
    Publication date: March 25, 2021
    Applicant: Industrial Technology Research Institute
    Inventors: Min-Yuan CHOU, Li-Tsen LIN, Chung-Yuan SUN, Ya-Ping LAI, Chin-Pen LAI, Ssu-Yuan WU, Mei-Wei LIN
  • Method for producing a multivalent fab fragment with collagen-like peptide
    Patent number: 10329350
    Abstract: The present invention relates to a method for producing multivalent Fab fragments. In particular, the invention relates to a method for the generation of trimeric Fab fragments by co-expression of a gene construct comprising a heavy chain portion of a Fab fragment and an in-frame fused collagen-like peptide, and a gene construct consisting of a light chain portion of an IgG in mammalian cells. Uses of molecules generated using the method of the invention are also described.
    Type: Grant
    Filed: February 7, 2013
    Date of Patent: June 25, 2019
    Assignee: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Min-Yuan Chou, Chuan-Chuan Huang, Hsiu-Chuan Li, Ya-Ping Lai
  • MULTIVALENT ANTIBODY FRAGMENTS AND TRIMERIZED COMPLEXES THEREOF
    Publication number: 20140178388
    Abstract: The present invention relates to a method for producing multivalent Fab fragments. In particular, the invention relates to a method for the generation of trimeric Fab fragments by co-expression of a gene construct comprising a heavy chain portion of a Fab fragment and an in-frame fused collagen-like peptide, and a gene construct consisting of a light chain portion of an IgG in mammalian cells. Uses of molecules generated using the method of the invention are also described.
    Type: Application
    Filed: February 7, 2013
    Publication date: June 26, 2014
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Min-Yuan CHOU, Chuan-Chuan HUANG, Hsiu-Chuan LI, Ya-Ping LAI
  • TNF receptor Fc fusion proteins and in vivo methods of use
    Patent number: 8669350
    Abstract: The embodiments of the invention relate to compositions, methods, and kits comprising a fusion protein. The fusion proteins of the embodiments include monomer polypeptides which in one embodiment have at least a binding domain, an optional hinge region, a collagen-like domain and the Fc domain of a human IgG.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: March 11, 2014
    Assignee: Industrial Technology Research Institute
    Inventors: Min-Yuan Chou, Wei-Chun Chiu, Ya-Ping Lai
  • Fc FUSION PROTEINS
    Publication number: 20130164286
    Abstract: The embodiments of the invention relate to compositions, methods, and kits comprising a fusion protein. The fusion proteins of the embodiments include monomer polypeptides which in one embodiment have at least a binding domain, an optional hinge region, a collagen-like domain and the Fc domain of a human IgG.
    Type: Application
    Filed: August 17, 2012
    Publication date: June 27, 2013
    Inventors: Min-Yuan CHOU, Wei-Chun Chiu, Ya-Ping Lai