Abstract: A medical cream applying apparatus includes an internal cream applicator which includes a handle member and an inserting head member. The handle member is ergonomically designed to allow a user's hand to grab thereon. The inserting head member is extended from the handle member, and has a round inserting portion having a diameter slightly larger than that of the handle member, wherein the round inserting portion is adapted to be soaked with a predetermined amount of medical cream, and is arranged to slightly insert into a vagina of a female user for evenly applying the medical cream in the vagina for treating a predetermined disease.