Patents by Inventor Yaara Birman

Yaara Birman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for modulating beta-catenin phosphorylation
    Publication number: 20050171005
    Abstract: The present invention provides modulators of ?-catenin phosphorylation. More specifically, the present invention provides inhibitors and enhancers of ?-catenin Serine 45 (S45) phosphorylation. Examples of inhibitors provided by the invention are the proteins Dishevelled (Dvl), Wnt, phosphatase PP2A and CKI7. Examples of enhancers of beta-catenin phosphorylation are phosphatase inhibitors and proteins that promote ?-catenin acetylation, like FRAT1. In addition, the present invention provides compositions and uses of the modulators of the invention, specifically for the treatment of cancer, as well as a method for screening such modulators.
    Type: Application
    Filed: October 25, 2004
    Publication date: August 4, 2005
    Inventors: Yinon Ben-Neriah, Irit Alkalay, Sharon Amit, Yaara Birman, Ada Hatzubai