Patents by Inventor Yabing Mu

Yabing Mu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cleavage inhibitors of transforming growth factor beta type I receptor and uses thereof in cancer therapy
    Patent number: 9296818
    Abstract: Disclosed herein are methods to inhibit cleavage of a type I receptor of transforming growth factor beta (T?RI) and reduce cancer cell invasiveness/metastasis, and agents and pharmaceutical compositions for use in these methods. Also disclosed herein are methods for identifying agents that inhibit cleavage of T?RI and methods for diagnosing and/or prognosing cancer based on nuclear localization of a intracellular domain of T?RI, which is a product of T?RI cleavage.
    Type: Grant
    Filed: March 13, 2012
    Date of Patent: March 29, 2016
    Inventors: Marene Inga-Britt Landstrom, Yabing Mu, Reshma Sundar, Noopur Thakur, Shyam Kumar Gudey, Maria Ekman, Carl-Henrik Heldin
  • CLEAVAGE INHIBITORS OF TRANSFORMING GROWTH FACTOR BETA TYPE I RECEPTOR AND USES THEREOF IN CANCER THERAPY
    Publication number: 20140377268
    Abstract: Disclosed herein are methods to inhibit cleavage of a type I receptor of transforming growth factor beta (T?RI) and reduce cancer cell invasiveness/metastasis, and agents and pharmaceutical compositions for use in these methods. Also disclosed herein are methods for identifying agents that inhibit cleavage of T?RI and methods for diagnosing and/or prognosing cancer based on nuclear localization of a intracellular domain of T?RI, which is a product of T?RI cleavage.
    Type: Application
    Filed: March 13, 2012
    Publication date: December 25, 2014
    Applicant: Ludwig Institute for Cancer Research Ltd.
    Inventors: Marene Inga-Britt Landstrom, Yabing Mu, Reshma Sundar, Noopur Thakur, Shyam Kumar Gudey, Maria Ekman, Carl-Henrik Heldin
  • CLEAVAGE INHIBITORS OF TRANSFORMING GROWTH FACTOR BETA TYPE I RECEPTOR AND USES THEREOF IN CANCER THERAPY
    Publication number: 20140140998
    Abstract: Disclosed herein are methods to inhibit cleavage of a type I receptor of transforming growth factor beta (T?RI) and reduce cancer cell invasiveness/metastasis, and agents and pharmaceutical compositions for use in these methods. Also disclosed herein are methods for identifying agents that inhibit cleavage of T?RI and methods for diagnosing and/or prognosing cancer based on nuclear localization of a intracellular domain of T?RI, which is a product of T?RI cleavage.
    Type: Application
    Filed: March 13, 2012
    Publication date: May 22, 2014
    Applicant: Ludwig Institute for Cancer Research Ltd.
    Inventors: Marene Inga-Britt Landstrom, Yabing Mu, Reshma Sundar, Noopur Thakur, Shyam Kumar Gudey, Maria Ekman, Carl-Henrik Heldin