Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Abstract: This disclosure relates to genetically modified animals and cells with humanized light chain immunoglobulin locus and/or humanized heavy chain immunoglobulin locus. In one aspect, the endogenous light chain immunoglobulin locus comprises a limit number of human IGKV genes and human IGKJ genes.

Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Abstract: This disclosure relates to genetically modified animals and cells with humanized light chain immunoglobulin locus and/or humanized heavy chain immunoglobulin locus. In one aspect, the endogenous light chain immunoglobulin locus comprises a limit number of human IGKV genes and human IGKJ genes.

Abstract: This application provides a network fault locating method and apparatus in an IP network. In this solution, a router automatically reports status information, and a controller determines, based on the status information, whether a communication path is faulty. If a fault exists, the controller may indicate a router on the communication path to perform fault locating. The fault locating can be completed without waiting for manual intervention, so that operation and maintenance efficiency in the IP network is improved. After completing the fault locating, the router reports location information of a fault point to the controller, and the controller may perform troubleshooting at the fault point, so that the fault can be quickly rectified.

Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Abstract: This disclosure relates to genetically modified animals and cells with humanized light chain immunoglobulin locus and/or humanized heavy chain immunoglobulin locus. In one aspect, the endogenous light chain immunoglobulin locus comprises a limit number of human IGKV genes and human IGKJ genes.

Abstract: This application provides a method for constructing a blockchain network based on an interior gateway protocol (IGP). A new IGP packet used to transmit a blockchain task is provided by extending the IGP. When receiving the new IGP packet, a network device can participate in execution of the blockchain task by using its idle computing power. The computing power of the network device is better utilized to construct the blockchain network, avoiding a waste of idle computing power of the network device.

Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Abstract: This application provides a packet processing method and related device, system, and storage medium, and pertains to the field of network technologies. This application provides a method for constructing a blockchain network based on an interior gateway protocol (IGP). A new IGP packet used to transmit a blockchain task is provided by extending the IGP. When receiving the new IGP packet, a network device can participate in execution of the blockchain task by using its idle computing power. The computing power of the network device is better utilized to construct the blockchain network, avoiding a waste of idle computing power of the network device. This improves the utilization of computing resources in the network device.

Abstract: This application provides a network fault locating method and apparatus in an IP network. In this solution, a router automatically reports status information, and a controller determines, based on the status information, whether a communication path is faulty. If a fault exists, the controller may indicate a router on the communication path to perform fault locating. The fault locating can be completed without waiting for manual intervention, so that operation and maintenance efficiency in the IP network is improved. After completing the fault locating, the router reports location information of a fault point to the controller, and the controller may perform troubleshooting at the fault point, so that the fault can be quickly rectified.

Abstract: The present disclosure relates to genetically modified animals and cells with humanized heavy chain immunoglobulin locus and/or humanized light chain immunoglobulin locus.

Abstract: In a load sharing method and a router device, each of the router devices in a load sharing relationship obtains load sharing information of all downstream router devices that are in a load sharing relationship with the router device, and when determining load sharing information of the router device, the router device determines the load sharing information of the router device according to the load sharing information of all the downstream router devices that are in a load sharing relationship with the router device, so that a disturbance factor of the router device is different from disturbance factors of all the downstream router devices that are in a load sharing relationship with the router device. Therefore, a coupling degree of load sharing information of all the router devices in a load sharing relationship in the network is reduced, and load sharing at all levels is even.

Abstract: In a load sharing method and a router device, each of the router devices in a load sharing relationship obtains load sharing information of all downstream router devices that are in a load sharing relationship with the router device, and when determining load sharing information of the router device, the router device determines the load sharing information of the router device according to the load sharing information of all the downstream router devices that are in a load sharing relationship with the router device, so that a disturbance factor of the router device is different from disturbance factors of all the downstream router devices that are in a load sharing relationship with the router device. Therefore, a coupling degree of load sharing information of all the router devices in a load sharing relationship in the network is reduced, and load sharing at all levels is even.