Patents by Inventor Yaein SHIM

Yaein SHIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FUSION PROTEIN COMPRISING ANTI-LAG-3 ANTIBODY AND IL-2, AND USE THEREOF
    Publication number: 20230257438
    Abstract: The present invention relates to a fusion protein comprising an anti-LAG-3 antibody and IL-2 or a variant thereof. In the fusion protein according to the present invention, the anti-LAG-3 antibody moiety may bind to LAG-3, thereby regulating the binding of LAG-3 and MHCII. Moreover, the IL-2 protein or a variant thereof may regulate the activity of T cells. Therefore, a pharmaceutical composition comprising the fusion protein increases the immune activity in vivo and can be effectively used as an anticancer agent, and thus is highly industrially applicable.
    Type: Application
    Filed: June 29, 2021
    Publication date: August 17, 2023
    Inventors: Myung Ho JANG, Young-Gyu CHO, Young Min OH, Yaein SHIM