Patents by Inventor Yael Pewzner-Jung

Yael Pewzner-Jung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190151424
    Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 23, 2019
    Inventors: Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
  • Patent number: 10159724
    Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: December 25, 2018
    Assignees: Icahn School of Medicine at Mount Sinai, Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
    Inventors: Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
  • Publication number: 20170020998
    Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
    Type: Application
    Filed: October 5, 2016
    Publication date: January 26, 2017
    Inventors: Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
  • Patent number: 9492514
    Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: November 15, 2016
    Assignees: Icahn School of Medicine at Mount Sinai, Universitaet Duisberg-Essen, Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
    Inventors: Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
  • Publication number: 20150258043
    Abstract: Methods of preventing or treating bacterial infections, including but not limited to Pseudomonas aeruginosa infections, by administering sphingoid long chain bases (LCB) are provided. The invention further relates to the use of sphingoid long chain bases, or pharmaceutical composition comprising same, for the treatment of lung diseases or disorders such as cystic fibrosis and chronic obstructive pulmonary disease.
    Type: Application
    Filed: October 15, 2013
    Publication date: September 17, 2015
    Inventors: Anthony Futerman, Yael Pewzner-Jung, Erich Gulbins
  • Publication number: 20150125439
    Abstract: The present invention relates to a method for treating or preventing pathogenic infections in a subject having Cystic Fibrosis, COPD, and/or an open wound. This method involves selecting a subject having Cystic Fibrosis, COPD, and/or an open wound and administering to the selected subject a ceramidase under conditions effective to reduce ceramide and to treat or prevent the pathogenic infection. The method also involves the use of a ceramidase in combination with other drugs to reduce infection, reduce ceramide, or improve lung function in Cystic Fibrosis, COPD, and/or open wound patients.
    Type: Application
    Filed: May 31, 2013
    Publication date: May 7, 2015
    Applicant: Universitatsstrasse 2
    Inventors: Edward H. Schuchman, Erich Gulbins, Anthony Futerman, Yael Pewzner-Jung
  • Publication number: 20090297515
    Abstract: A method of inhibiting hematopoiesis in a subject is provided. The method is effected by downregulating an expression or activity of caspase-8 in the subject thereby inhibiting hematopoiesis therein.
    Type: Application
    Filed: May 26, 2009
    Publication date: December 3, 2009
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO., LTD.
    Inventors: David Wallach, Eugene Varfolomeev, Yael Pewzner-Jung, Tae-Bong Kang, Tehila B. Moshe
  • Publication number: 20070269419
    Abstract: A method of inhibiting hematopoiesis in a subject is provided. The method is effected by downregulating an expression or activity of caspase-8 in the subject thereby inhibiting hematopoiesis therein.
    Type: Application
    Filed: October 26, 2004
    Publication date: November 22, 2007
    Applicant: Yeda Research And Development
    Inventors: David Wallach, Eugene Varfolomeev, Yael Pewzner-Jung, Tae-Bong Kang, Tehila Moshe