Patents by Inventor Yael Wexler-Cohen

Yael Wexler-Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • VEGFR-FC FUSION PROTEIN FORMULATIONS
    Publication number: 20230025418
    Abstract: VEGFR-Fc fusion protein formulations and methods of making using such formulations are provided herein. In one embodiment, the formulation is an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the VEGFR-Fc fusion protein is aflibercept.
    Type: Application
    Filed: September 14, 2022
    Publication date: January 26, 2023
    Applicant: Amgen Inc.
    Inventors: Yael WEXLER-COHEN, Robert Matthew FESINMEYER, Monica Michelle GOSS, Sekhar KANAPURAM, Rahul Rajan KAUSHIK, Sai Chakradhar PADALA
  • FORMULATIONS COMPRISING A TRIS BUFFER AND A PROTEIN
    Publication number: 20210353713
    Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept. In some embodiments, the formulation comprises a Tris buffer.
    Type: Application
    Filed: October 25, 2019
    Publication date: November 18, 2021
    Applicant: AMGEN INC.
    Inventors: Yael WEXLER-COHEN, Robert Matthew FESINMEYER, Rahul Rajan KAUSHIK
  • METHODS FOR MAKING STABLE PROTEIN COMPOSITIONS
    Publication number: 20210163531
    Abstract: The invention relates to methods for preparing stable buffered and buffer-free protein compositions. The invention also relates to methods of purifying proteins from one or more impurities.
    Type: Application
    Filed: March 28, 2019
    Publication date: June 3, 2021
    Inventors: William Callahan, Lorenzo Desantiago, Clea Talley, Yael Wexler-Cohen, Jeffrey Abel, Rahul Kaushik, Nitya Mariam Jacob, Carson Tran, Nicole Ball, Monica Goss
  • VEGFR-FC FUSION PROTEIN FORMULATIONS
    Publication number: 20200338164
    Abstract: Protein formulations and methods of making and using such formulations are provided herein. The formulation can be an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the formulation comprises a VEGFR-Fc fusion protein, such as aflibercept.
    Type: Application
    Filed: November 16, 2018
    Publication date: October 29, 2020
    Applicant: AMGEN INC.
    Inventors: Yael WEXLER-COHEN, William J. CALLAHAN, Robert Matthew FESINMEYER, Rahul Rajan KAUSHIK, Sai Chakradhar PADALA
  • VEGFR-FC FUSION PROTEIN FORMULATIONS
    Publication number: 20200255496
    Abstract: VEGFR-Fc fusion protein formulations and methods of making using such formulations are provided herein. In one embodiment, the formulation is an ophthalmic formulation, such as for intravitreal administration. In some embodiments, the VEG-FR-Fc fusion protein is aflibercept.
    Type: Application
    Filed: September 17, 2018
    Publication date: August 13, 2020
    Applicant: AMGEN INC.
    Inventors: Yael WEXLER-COHEN, Robert Matthew FESINMEYER, Monica Michelle GOSS, Sekhar KANAPURAM, Rahul Rajan KAUSHIK, Sai Chakradhar PADALA
  • LIPOPEPTIDE INHIBITORS OF HIV-1
    Publication number: 20120028887
    Abstract: The invention provides lipophilic conjugates comprising a short isolated peptide coupled to a hydrophobic moiety, the peptide comprising a sequence derived from the HIV-1 gp41 N-terminal heptad repeat domain, said peptide after conjugation to the hydrophobic moiety possesses anti-fusogenic activity higher than prior to conjugation. The lipophilic conjugates are suitable for treatment of infections caused by human and non-human retroviruses, especially HIV.
    Type: Application
    Filed: March 28, 2010
    Publication date: February 2, 2012
    Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
    Inventors: Yechiel Shai, Yael Wexler-Cohen