Patents by Inventor Yafei Xie

Yafei Xie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240058702
    Abstract: A method for controlling movement of a virtual object in a virtual environment is performed at a terminal.
    Type: Application
    Filed: November 2, 2023
    Publication date: February 22, 2024
    Inventors: Yafei XIE, Chong HUO
  • Patent number: 11839816
    Abstract: A method for controlling movement of a virtual object in a virtual environment is performed at a terminal. The method includes: obtaining first recorded trajectory information, the first recorded trajectory information being information that is recorded when a first user account of an online gaming application controls a first virtual object to race in a virtual scene and is used for drawing a movement trajectory of the first virtual object; displaying a racing battle interface, the racing battle interface being used for presenting a racing battle including a second virtual object and a third virtual object, the second virtual object being a virtual object controlled by a second user account of the online gaming application, the third virtual object being a virtual object controlled by a computer; and controlling movement of the third virtual object according to the first recorded trajectory information in the racing battle.
    Type: Grant
    Filed: August 11, 2021
    Date of Patent: December 12, 2023
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Yafei Xie, Chong Huo
  • Publication number: 20210370176
    Abstract: A method for controlling movement of a virtual object in a virtual environment is performed at a terminal. The method includes: obtaining first recorded trajectory information, the first recorded trajectory information being information that is recorded when a first user account of an online gaming application controls a first virtual object to race in a virtual scene and is used for drawing a movement trajectory of the first virtual object; displaying a racing battle interface, the racing battle interface being used for presenting a racing battle including a second virtual object and a third virtual object, the second virtual object being a virtual object controlled by a second user account of the online gaming application, the third virtual object being a virtual object controlled by a computer; and controlling movement of the third virtual object according to the first recorded trajectory information in the racing battle.
    Type: Application
    Filed: August 11, 2021
    Publication date: December 2, 2021
    Inventors: Yafei XIE, Chong HUO
  • Patent number: 11149013
    Abstract: The present invention provides a crystal form of urate transporter 1 inhibitor and a preparation method and use thereof. The crystal form is characterized by a stable state of appearance and a capability of further improving the purity and storage stability of the compound, etc., and suitable as a pharmaceutical raw material.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: October 19, 2021
    Assignee: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.
    Inventors: Guilong Zhao, Changying Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Xuyuan Liu, Yuqiang Liu, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Lida Tang, Meixiang Zou
  • Patent number: 11091448
    Abstract: Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: August 17, 2021
    Assignee: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.
    Inventors: Guilong Zhao, Changying Liu, Yuqiang Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Meixiang Zou, Lida Tang
  • Publication number: 20200369628
    Abstract: The present invention provides a crystal form of urate transporter 1 inhibitor and a preparation method and use thereof. The crystal form is characterized by a stable state of appearance and a capability of further improving the purity and storage stability of the compound, etc., and suitable as a pharmaceutical raw material.
    Type: Application
    Filed: January 18, 2019
    Publication date: November 26, 2020
    Applicant: Tianjin Institute of Pharmaceutical Research Co., Ltd.
    Inventors: Guilong Zhao, Changying Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Xuyuan Liu, Yuqiang Liu, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Lida Tang, Meixiang Zou
  • Patent number: 10584104
    Abstract: The present invention relates to the pharmaceutical field for the treatment of hyperuricemia and gout. In particular, the present invention relates to a carboxylic acid urate transporter 1 (URAT1) inhibitor of a general formula (I) containing a diarylmethane structure and a preparation method thereof, and a pharmaceutical composition containing the same and a use thereof in the preparation of medicaments for treating hyperuricemia and gout, wherein R1 is selected from H, C1-C10 alkyl, C3-C10 cycloalkyl, F, Cl, Br, I, CN, NO2, SR4 or OR4; R2 is selected from H, F, Cl, Br or I; R3 is selected from H or C1-C4 alkyl; X is selected from S or CH2; wherein R4 is selected from C1-C10 alkyl.
    Type: Grant
    Filed: April 28, 2016
    Date of Patent: March 10, 2020
    Assignee: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH CO., LTD.
    Inventors: Guilong Zhao, Wei Liu, Qian Shang, Zhixing Zhou, Yuli Wang, Yuquan Li, Haizhi Zhang, Chuan Li, Changying Liu, Yuqiang Liu, Yafei Xie, Jingwei Wu, Huihui Chen, Weiren Xu, Lida Tang
  • Publication number: 20190233381
    Abstract: Provided is a method for preparing a URAT1 inhibitor, 2-((5-bromo-4-((4-bromonaphthalen-1-yl)methyl)-4H-1,2,4-triazol-3-yl)thio) acetic acid represented by the following formula ZXS-BR, the reaction equation of which being shown as follows. Compared with the prior art, the preparation method provided by the present application is of low cost, ease of handling, ease of quality control, and applicable to industrialization.
    Type: Application
    Filed: June 26, 2017
    Publication date: August 1, 2019
    Inventors: Guilong Zhao, Changying Liu, Yuqiang Liu, Huihui Chen, Yuquan Li, Haizhi Zhang, Yafei Xie, Jingwei Wu, Wei Liu, Weiren Xu, Meixiang Zou, Lida Tang
  • Patent number: 10294259
    Abstract: The present invention provides a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, a pharmaceutical composition comprising the same, and uses thereof in the preparation of medicaments for treating diabetes, wherein substituents R1-R7 are as defined in the specification. The present invention also provides a method for synthesizing the phenyl C-glucoside derivative containing a deoxyglucose structure and an intermediate product. The method has advantages of being simple to manage and of low cost, which is suitable for large-scale industrial production. The present invention further provides a cocrystal of (1S)-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1,6-dideoxy-D-glucose and L-proline, and preparation method and uses thereof.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: May 21, 2019
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Yuli Wang, Bingni Liu, Yafei Xie, Yuqiang Liu, Peng Liu, Jiang Wu, Jiajia Hou, Wei Wei, Wen Du, Weiren Xu, Lida Tang, Meixiang Zou
  • Publication number: 20180134670
    Abstract: The present invention relates to the pharmaceutical field for the treatment of hyperuricemia and gout. In particular, the present invention relates to a carboxylic acid urate transporter 1 (URAT1) inhibitor of a general formula (I) containing a diarylmethane structure and a preparation method thereof, and a pharmaceutical composition containing the same and a use thereof in the preparation of medicaments for treating hyperuricemia and gout, wherein R1 is selected from H, C1-C10 alkyl, C3-C10 cycloalkyl, F, Cl, Br, I, CN, NO2, SR4 or OR4; R2 is selected from H, F, Cl, Br or I; R3 is selected from H or C1-C4 alkyl; X is selected from S or CH2; wherein R4 is selected from C1-C10 alkyl.
    Type: Application
    Filed: April 28, 2016
    Publication date: May 17, 2018
    Inventors: GUILONG ZHAO, WEI LIU, QIAN SHANG, ZHIXING ZHOU, YULI WANG, YUQUAN LI, HAIZHI ZHANG, CHUAN LI, CHANGYING LIU, YUQIANG LIU, YAFEI XIE, JINGWEI WU, HUIHUI CHEN, WEIREN XU, LIDA TANG
  • Publication number: 20170057989
    Abstract: The present invention provides a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, a pharmaceutical composition comprising the same, and uses thereof in the preparation of medicaments for treating diabetes, wherein substituents R1-R7 are as defined in the specification. The present invention also provides a method for synthesizing the phenyl C-glucoside derivative containing a deoxyglucose structure and an intermediate product. The method has advantages of being simple to manage and of low cost, which is suitable for large-scale industrial production. The present invention further provides a cocrystal of (1S)-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1,6-dideoxy-D-glucose and L-proline, and preparation method and uses thereof.
    Type: Application
    Filed: November 11, 2016
    Publication date: March 2, 2017
    Applicant: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Yuli Wang, Bingni Liu, Yafei Xie, Yuqiang Liu, Peng Liu, Jiang Wu, Jiajia Hou, Wei Wei, Wen Du, Weiren Xu, Lida Tang, Meixiang Zou
  • Patent number: 9505734
    Abstract: The present invention provides a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, a pharmaceutical composition comprising the same, and uses thereof in the preparation of medicaments for treating diabetes, wherein substituents R1-R7 are as defined in the specification. The present invention also provides a method for synthesizing the phenyl C-glucoside derivative containing a deoxyglucose structure and an intermediate product. The method has advantages of being simple to manage and of low cost, which is suitable for large-scale industrial production. The present invention further provides a cocrystal of (1S)-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1,6-dideoxy-D-glucose and L-proline, and preparation method and uses thereof.
    Type: Grant
    Filed: December 5, 2013
    Date of Patent: November 29, 2016
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Yuli Wang, Bingni Liu, Yafei Xie, Yuqiang Liu, Peng Liu, Jiang Wu, Jiajia Hou, Wei Wei, Wen Du, Weiren Xu, Lida Tang, Meixiang Zou
  • Publication number: 20160046595
    Abstract: The present invention provides a phenyl C-glucoside derivative containing a deoxyglucose structure as represented by formula I, preparation method thereof, a pharmaceutical composition comprising the same, and uses thereof in the preparation of medicaments for treating diabetes, wherein substituents R1-R7 are as defined in the specification. The present invention also provides a method for synthesizing the phenyl C-glucoside derivative containing a deoxyglucose structure and an intermediate product. The method has advantages of being simple to manage and of low cost, which is suitable for large-scale industrial production. The present invention further provides a cocrystal of (1S)-1-[4-chloro-3-(4-ethoxybenzyl)phenyl]-1,6-dideoxy-D-glucose and L-proline, and preparation method and uses thereof.
    Type: Application
    Filed: December 5, 2013
    Publication date: February 18, 2016
    Applicant: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Yuli Wang, Bingni Liu, Yafei Xie, Yuqiang Liu, Peng Liu, Jiang Wu, Jiajia Hou, Wei Wei, Wen Du, Weiren Xu, Lida Tang, Meixiang Zou