Patents by Inventor Yair Argon

Yair Argon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for the Diagnosis and Treatment of Primary Insulin-Like Growth Factor Deficiency (PIGFD) and Idiopathic Short Stature (ISS)
    Publication number: 20130261059
    Abstract: Compositions and methods for identifying patients at increased risk for PIGFD and ISS are disclosed.
    Type: Application
    Filed: May 26, 2011
    Publication date: October 3, 2013
    Applicant: THE CHILDREN'S HOSPITAL OF PHILADELPHIA
    Inventors: Yair Argon, Adda Grimberg
  • GRP94-based compositions and methods of use thereof
    Patent number: 7589174
    Abstract: Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided. Also provided are tools to facilitate screening therapeutic agents which have selective binding affinity for GRP94.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: September 15, 2009
    Assignees: The Children's Hospital of Philadelphia, The University of Chicago
    Inventors: Yair Argon, Tali Gidalevitz, Chhanda Biswas
  • GRP94-BASED COMPOSITIONS AND METHODS OF USE THEREOF
    Publication number: 20080199486
    Abstract: Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided. Also provided are tools to facilitate screening therapeutic agents which have selective binding affinity for GRP94.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 21, 2008
    Inventors: Yair Argon, Chhanda Biswas, Olga Ostrovsky
  • GRP94-based compositions and methods of use thereof
    Publication number: 20060029610
    Abstract: Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided. Also provided are tools to facilitate screening therapeutic agents which have selective binding affinity for GRP94.
    Type: Application
    Filed: October 12, 2004
    Publication date: February 9, 2006
    Inventors: Yair Argon, Tali Gidalevitz, Chhanda Biswas, Birgitte Simen, Sherry Wanderling, Olga Ostrovsky
  • Fibril-blocking peptide, a method for preventing fibril formation
    Patent number: 6878521
    Abstract: A method of minimizing the aggregation tendencies of an amyloid forming protein is provided comprising identifying a portion of the protein that is critical to amyloid formation; and inserting a peptide at the portion. The invention also provides a peptide for insertion in an intact human kappa-IV light chain variable domain, the peptide comprising the following amino acid sequence Phe71-Thr72-Leu73-Thr74-Ile75-Ser76-Ser77 (SEQ ID NO. 1) wherein the subscript numbers are the residue location points in the domain. A method for preventing amyloid formation in human kappa-IV light chain variable domain is also provided, the method comprising inserting the peptide Phe1-Thr72-Leu73-Thr74-Ile75-Ser76-Ser77 (SEQ ID NO. 1) into the domain, wherein the subscript numbers indicate the residue location on the domain.
    Type: Grant
    Filed: November 13, 2000
    Date of Patent: April 12, 2005
    Assignee: The University of Chicago
    Inventors: Fred J. Stevens, Yair Argon, David P. Davis, Rosemarie Raffen
  • GRP94-based compositions and methods of use thereof
    Publication number: 20050063982
    Abstract: Mini chaperones and methods of use thereof for the treatment of cancer and other disorders are provided.
    Type: Application
    Filed: May 12, 2004
    Publication date: March 24, 2005
    Inventors: Yair Argon, Tali Gidalevitz, Chhanda Biswas, Birgitte Simen, Sherry Wanderling, Olga Ostrovsky