Patents by Inventor Yair BENITA

Yair BENITA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20240025973
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: September 1, 2023
    Publication date: January 25, 2024
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • PVRIG polypeptides and methods of treatment
    Patent number: 11795209
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Grant
    Filed: January 28, 2020
    Date of Patent: October 24, 2023
    Assignee: COMPUGEN LTD.
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • METHODS FOR TREATING CANCER WITH A WEE1 INHIBITOR
    Publication number: 20230083689
    Abstract: The present invention relates generally to the use of gene mutations, whose presence or absence are useful for predicting a patient's response to treatment with an anti-proliferative agent, in particular a WEE1 inhibitor. The presence or absence of a mutation to the TP53 gene, can be used to predict response to treatment with a WEE1 inhibitor in a patient presenting with a cancerous condition.
    Type: Application
    Filed: May 23, 2022
    Publication date: March 16, 2023
    Inventors: Matthew J. MARTON, Yair BENITA
  • Methods for treating cancer with a WEE1 inhibitor
    Patent number: 11364243
    Abstract: The present invention relates generally to the use of gene mutations, whose presence or absence are useful for predicting a patient's response to treatment with an anti-proliferative agent, in particular a WEE1 inhibitor. The presence or absence of a mutation to the TP53 gene, can be used to predict response to treatment with a WEE1 inhibitor in a patient presenting with a cancerous condition.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: June 21, 2022
    Assignee: MERCK SHARP & DOHME CORP.
    Inventors: Matthew J. Marton, Yair Benita
  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20200385445
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: January 28, 2020
    Publication date: December 10, 2020
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • METHODS FOR TREATING CANCER WITH A WEE1 INHIBITOR
    Publication number: 20200171035
    Abstract: The present invention relates generally to the use of gene mutations, whose presence or absence are useful for predicting a patient's response to treatment with an anti-proliferative agent, in particular a WEE1 inhibitor. The presence or absence of a mutation to the TP53 gene, can be used to predict response to treatment with a WEE1 inhibitor in a patient presenting with a cancerous condition.
    Type: Application
    Filed: December 6, 2019
    Publication date: June 4, 2020
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Matthew J. MARTON, Yair BENITA
  • PVRIG polypeptides and methods of treatment
    Patent number: 10550173
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 4, 2020
    Assignee: Compugen, Ltd.
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • HIDE1 COMPOSITIONS AND METHODS
    Publication number: 20180305451
    Abstract: According to at least some embodiments of the present invention is directed to anti-HIDE1 antibodies and polypeptides and methods of using same.
    Type: Application
    Filed: July 13, 2016
    Publication date: October 25, 2018
    Inventors: Yosef DICKEN, Liat DASSA, Amit NOVIK, Amir TOPORIK, Gad COJOCARU, Yossef KLIGER, Yair BENITA, Ofer LEVY, Ilan VAKNIN, Arthur MACHLENKIN, Iris HECHT, Jungmin KIM, Andrew POW, Andrew W DRAKE
  • Methods for Treating Cancer with a WEE1 Inhibitor
    Publication number: 20170095479
    Abstract: The present invention relates generally to the use of gene mutations, whose presence or absence are useful for predicting a patient's response to treatment with an anti-proliferative agent, in particular a WEE1 inhibitor. The presence or absence of a mutation to the TP53 gene, can be used to predict response to treatment with a WEE1 inhibitor in a patient presenting with a cancerous condition.
    Type: Application
    Filed: May 26, 2015
    Publication date: April 6, 2017
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Matthew J. MARTON, Yair BENITA
  • PVRIG POLYPEPTIDES AND METHODS OF TREATMENT
    Publication number: 20170088607
    Abstract: The present invention is directed to PVRIG polypeptides and their uses.
    Type: Application
    Filed: February 19, 2016
    Publication date: March 30, 2017
    Inventors: Mark White, Sandeep Kumar, Christopher Chan, Spencer Liang, Lance Stapleton, Andrew W. Drake, Yosi Gozlan, Ilan Vaknin, Shirley Sameah-Greenwald, Liat Dassa, Zohar Tiran, Gad. S. Cojocaru, Amir Toporik, Yossef Kliger, Ofer Levy, Arthur Machlenkin, Sergey Nemzer, Yair Benita, Amit Novik
  • Compositions and Methods for Treating Cancer
    Publication number: 20140349968
    Abstract: The instant invention provides a method of treating a cancer selected from the group consisting of non-small cell lung cancer and breast cancer with an mTOR inhibitor and an ?v62 3 integrin antagonist, wherein the mTOR inhibitor is ridaforolimus, everolimus, temsirolimus or a combination thereof.
    Type: Application
    Filed: April 30, 2014
    Publication date: November 27, 2014
    Applicants: ARIAD Pharmaceuticals, Inc., Merck
    Inventors: Jennifer O'Neil, Yair Benita, Shane Marine, Brian Haines
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20120289481
    Abstract: The instant invention provides a method of treating a cancer selected from the group consisting of non-small cell lung cancer and breast cancer with an mTOR inhibitor and an ?v?3 integrin antagonist, wherein the mTOR inhibitor is ridaforolimus, everolimus, temsirolimus or a combination thereof.
    Type: Application
    Filed: May 4, 2012
    Publication date: November 15, 2012
    Inventors: Jennifer O'NEIL, Yair BENITA, Shane MARINE, Brian HAINES