Abstract: In one embodiment, a cold storage system for biological samples has one or more freezers, each freezer having one or racks, each rack receiving one or more boxes, each box receiving one or more sample containers. In addition to the biological sample, each sample container has a unique passive RFID tag. Control electronics in each box energize reader coils to query individual RFID tags. Control electronics in each rack communicate with and provide power to the control electronics of each corresponding box, and control electronics in each freezer communicate with and provide power to the control electronics of each corresponding rack, and a host computer communicates with the control electronics in each freezer. In each instance, communication and power provisioning is implemented using magnetic inductive coupling. The system is able to determine the identity of each sample container in the system and maintain that information in a database.

Abstract: In one embodiment, a cold storage system for biological samples has one or more freezers, each freezer having one or racks, each rack receiving one or more boxes, each box receiving one or more sample containers. In addition to the biological sample, each sample container has a unique passive RFID tag. Control electronics in each box energize reader coils to query individual RFID tags. Control electronics in each rack communicate with and provide power to the control electronics of each corresponding box, and control electronics in each freezer communicate with and provide power to the control electronics of each corresponding rack, and a host computer communicates with the control electronics in each freezer. In each instance, communication and power provisioning is implemented using magnetic inductive coupling. The system is able to determine the identity of each sample container in the system and maintain that information in a database.

Abstract: A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals form the detector, and passes these signals to memory for accumulation and storage, and then to image processing engine for determination of the localization and distribution of the contrast agent.

Abstract: A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals from the detector, and passes these signals to memory for accumulation and storage, and to then to image processing engine for determination of the localization and distribution of the contrast agent.

Abstract: In one embodiment, a cold storage system for biological samples has one or more freezers, each freezer having one or racks, each rack receiving one or more boxes, each box receiving one or more sample containers. In addition to the biological sample, each sample container has a unique passive RFID tag. Control electronics in each box energize reader coils to query individual RFID tags. Control electronics in each rack communicate with and provide power to the control electronics of each corresponding box, and control electronics in each freezer communicate with and provide power to the control electronics of each corresponding rack, and a host computer communicates with the control electronics in each freezer. In each instance, communication and power provisioning is implemented using magnetic inductive coupling. The system is able to determine the identity of each sample container in the system and maintain that information in a database.

Abstract: A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals from the detector, and passes these signals to memory for accumulation and storage, and to then to image processing engine for determination of the localization and distribution of the contrast agent.

Abstract: A method for detecting and localizing a target tissue within the body in the presence of ambient light in which an optical contrast agent is administered and allowed to become functionally localized within a contrast-labeled target tissue to be diagnosed. A light source is optically coupled to a tissue region potentially containing the contrast-labeled target tissue. A gated light detector is optically coupled to the tissue region and arranged to detect light substantially enriched in target signal as compared to ambient light, where the target signal is light that has passed into the contrast-labeled tissue region and been modified by the contrast agent. A computer receives signals from the detector, and passes these signals to memory for accumulation and storage, and to then to image processing engine for determination of the localization and distribution of the contrast agent.

Abstract: An Interline charge coupled device is utilized to capture events during a short duration of time. The Interline charge coupled device is connected to a controller which causes charge to begin being accumulating at the beginning of the time window of interest, and shifts the charge underneath the shielded portion of the Interline charge coupled device at the end of such time. Various applications including spectroscopy and imaging are disclosed as well.

Abstract: An improved coating for a charged coupled device is disclosed which eliminates problems caused by prior coatings. The coating does not significantly decrease quantum efficiency in any spectral range of interest.

Abstract: A CCD comprises a sensing array and a readout register extending adjacent an edge of the sensing array. The readout register has first and second rows of transfer cells. The first row of transfer cells is between the sensing array and the second row. The transfer cells of the first row are of lower capacity than the transfer cells of the second row and are separated from the transfer cells of the second row by a potential barrier.

Abstract: An optical fiber polychromator for separating light radiation into spectral bands which can be simultaneously displayed in a stacked, two-dimensional non-overlapping arrangement. Light radiation is directed through entrance slits into a Rowland Circle spectrometer apparatus by optical fibers which are arranged at discrete locations on an entrance focal plane. The radiation is separated into spectral windows or bands which are focused in parallel onto the target of a vidicon detector. The discrete entrance locations are defined in accordance with column and row coordinates of a matrix in the entrance focal plane wherein the column and row coordinates are separated by predetermined distances dependent upon the dimensions of the detector target and the entrance slits. The entrance locations are arranged so that no two locations have the same row or column coordinate whereby the desired parallel, non-overlapping distribution of spectral bands is achieved.

Abstract: Carbonized resin microspheroids are used as a column packing in gas-solid chromatography and as a support in gas-liquid chromatography.