Abstract: Disclosed in the present invention are an antibody targeting LAG-3, a preparation method therefor and the use thereof. In particular, disclosed in the present invention is a novel monoclonal antibody targeting LAG-3. Also disclosed in the present invention is a method for the preparation of the monoclonal antibody. The monoclonal antibody of the present invention is capable of binding LAG-3 antigens with high specificity, and has very high affinity and significant activities such as anti-tumor activity.

Abstract: A method for forming a 3D NAND memory device is provided. The method includes: providing a semiconductor structure including a semiconductor substrate, a stacked structure, and a dielectric layer covering the semiconductor substrate and the stacked structure; forming, in the dielectric layer and the stacked structure, channel through vias penetrating through the stacked structure; forming a channel structure in each channel through via, and sequentially forming a polysilicon layer, a first metal silicide layer located on the polysilicon layer, and a through via contact metal layer located on the first metal silicide layer in the channel structure; forming a first through via in the dielectric layer for exposing the semiconductor substrate after forming the first metal silicide layer; forming a second metal silicide layer at a bottom of the first through via; and forming a first contact plug connected to the second metal silicide layer in the first through via.

Abstract: An antibody targeting CD73, a preparation method therefor and a use thereof. The provided monoclonal antibody can bind to a CD73 antigen with high specificity, and has high affinity and significant antitumor activity.

Abstract: Disclosed in the present invention are an antibody targeting LAG-3, a preparation method therefor and the use thereof. In particular, disclosed in the present invention is a novel monoclonal antibody targeting LAG-3. Also disclosed in the present invention is a method for the preparation of the monoclonal antibody. The monoclonal antibody of the present invention is capable of binding LAG-3 antigens with high specificity, and has very high affinity and significant activities such as anti-tumor activity.

Abstract: A bulldozer according to the present application includes a main frame, and an engine, a hood and an exhaust after-treatment device are provided on the main frame, an air inlet of the exhaust after-treatment device is in communication with an air outlet of a turbine of the engine via a pipeline, and the exhaust after-treatment device is fixed to the hood. In the bulldozer, vibration generated by the engine is transmitted to the main frame through an engine supporting frame or a damping device, and then transmitted from the main frame to the hood, the transmission path of the vibration is long, thus the vibration damping becomes complicated and has a high damping value, and the vibration transmitted to the air cleaner is really small.

Abstract: A bulldozer according to the present application includes a main frame, and an engine, a hood and an exhaust after-treatment device are provided on the main frame, an air inlet of the exhaust after-treatment device is in communication with an air outlet of a turbine of the engine via a pipeline, and the exhaust after-treatment device is fixed to the hood. In the bulldozer, vibration generated by the engine is transmitted to the main frame through an engine supporting frame or a damping device, and then transmitted from the main frame to the hood, the transmission path of the vibration is long, thus the vibration damping becomes complicated and has a high damping value, and the vibration transmitted to the air cleaner is really small.