Abstract: A catheter drainage and protection unit for venting urine drainage and collecting urine samples while preventing inadvertent spillage of urine due to overflow. A slender cannula is entered longitudinally of the penis in the urethra, the distal end thereof reaching into the male bladder. A foley catheter integral with the distal end of the cannula is inflated by appropriate medicinal fluid to prevent dislodgement of the catheter from the bladder. A flexible cap is disposed about the head of the penis circumscribing the cannula, the narrow outlet of the flexible cap being coupled about one branch of a tube leading to a flexible collection container. The cannula exits the flexible cap in a concentric relationship therewith entering the end portion of a first branch of the drainage tubing.