Patents by Inventor Yali Chen

Yali Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12583933
    Abstract: The present invention relates to the field of disease therapy and immunology. Specifically, disclosed are an anti-CD73 antibody or an antigen-binding fragment thereof, a nucleic acid molecule encoding same, an immunoconjugate comprising same, a bispecific molecule and a pharmaceutical composition, as well as use thereof in enhancing immune response and/or treating tumors.
    Type: Grant
    Filed: August 28, 2020
    Date of Patent: March 24, 2026
    Assignee: BIOTHEUS INC.
    Inventors: Liang Du, Hongyan Zhang, Lina Jin, Yali Chen, Jijun Yuan, Zhenqing Zhang, Xiaoniu Miao, Weifeng Huang, Yunli Jia
  • Publication number: 20250219164
    Abstract: A positive electrode plate includes a positive electrode current collector and a positive electrode active material layer. A safety coating is provided between the positive electrode current collector and the positive electrode active material layer, and the safety coating is disposed on a surface of the positive electrode current collector. The safety coating contains substance I, and the substance I is formed by dehydration of a first substance via a drying process of the positive electrode plate, where the first substance includes silica sol and/or alumina sol. The surface of the current collector of the positive electrode plate is provided with the safety coating, where the safety coating has good high-temperature resistance and can effectively protect the aluminum foil at high temperatures, thereby enhancing the thermal safety performance of the lithium-ion battery.
    Type: Application
    Filed: December 27, 2024
    Publication date: July 3, 2025
    Applicant: Ningde Amperex Technology Limited
    Inventor: Yali CHEN
  • Publication number: 20240150455
    Abstract: Provided are an anti-CLDN6 antibody or an antigen-binding fragment thereof; a nucleic acid molecule encoding same; an immunoconjugate, a bispecific molecule, a chimeric antigen receptor and a pharmaceutical composition containing same; and the use thereof for preventing and/or treating tumors.
    Type: Application
    Filed: March 5, 2021
    Publication date: May 9, 2024
    Inventors: Liang Du, Hongyan Zhang, Lina Jin, Yali Chen, Tingting Wan, Liuliu Xu, Jijun Yuan
  • Publication number: 20230312739
    Abstract: The present invention relates to the field of disease therapy and immunology. Specifically, disclosed are an anti-CD73 antibody or an antigen-binding fragment thereof, a nucleic acid molecule encoding same, an immunoconjugate comprising same, a bispecific molecule and a pharmaceutical composition, as well as use thereof in enhancing immune response and/or treating tumors.
    Type: Application
    Filed: August 28, 2020
    Publication date: October 5, 2023
    Inventors: Liang DU, Hongyan ZHANG, Lina JIN, Yali CHEN, Jijun YUAN, Zhenqing ZHANG, Xiaoniu MIAO, Weifeng HUANG, Yunli JIA
  • Patent number: 11638952
    Abstract: A steelmaking-and-continuous-casting dispatching method and apparatus based on a distributed robust chance-constraint model. The method includes: according to parameters, an objective function and a constraint condition in steelmaking-and-continuous-casting dispatching, establishing the distributed robust chance-constraint model; by using a dual-approximation method or a linear-programming-approximation method, solving the distributed robust chance-constraint model, to obtain processing starting durations of cast batches in conticasters and processing starting durations of furnace batches in machines other than the conticasters; and by using a solved result of the distributed robust chance-constraint model as an evaluation criterion, by using a tabu-search algorithm, determining a furnace-batch sequence and a distribution theme in the steelmaking-and-continuous-casting dispatching.
    Type: Grant
    Filed: March 30, 2022
    Date of Patent: May 2, 2023
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Shiji Song, Shengsheng Niu, Yali Chen
  • Publication number: 20220324014
    Abstract: A steelmaking-and-continuous-casting dispatching method and apparatus based on a distributed robust chance-constraint model. The method includes: according to parameters, an objective function and a constraint condition in steelmaking-and-continuous-casting dispatching, establishing the distributed robust chance-constraint model; by using a dual-approximation method or a linear-programming-approximation method, solving the distributed robust chance-constraint model, to obtain processing starting durations of cast batches in conticasters and processing starting durations of furnace batches in machines other than the conticasters; and by using a solved result of the distributed robust chance-constraint model as an evaluation criterion, by using a tabu-search algorithm, determining a furnace-batch sequence and a distribution theme in the steelmaking-and-continuous-casting dispatching.
    Type: Application
    Filed: March 30, 2022
    Publication date: October 13, 2022
    Applicant: Tsinghua University
    Inventors: Shiji SONG, Shengsheng NIU, Yali CHEN
  • Publication number: 20220255217
    Abstract: The present disclosure relates to an antenna angle adjustment device, and the angle adjustment device includes a drive member (10) and a driven member (4). The drive member is supported rotatably around a first rotation axis (X1) and can be manipulated and fixed. The driven member is supported rotatably around a second rotation axis (X2), and the angular position of the driven member is related to the angular position of the antenna. The drive member has an engagement point, and the driven member has a concave curved portion. The engagement point extends into the curved portion and engages the curved portion so that the rotation of the drive member around the first rotation axis can cause the rotation of the driven member around the second rotation axis. The present disclosure further relates to an antenna with the angle adjustment device. The angle of the antenna can be appropriately adjusted by the angle adjustment device.
    Type: Application
    Filed: January 13, 2022
    Publication date: August 11, 2022
    Inventors: ZiCheng Su, Yali Chen
  • Patent number: 8297080
    Abstract: A method for producing a single-mode fiber for submarine cables including washing and flame polishing of a preform, fiber drawing, coating with a first coating layer and curing therein using an UV-curing device, coating with a second coating layer and curing therein using the UV-curing device, fiber selection with a 2% screening strain, and testing the properties of the fiber. The fiber has a high strength and long coiling length exceeding 100 km and the method is easy to practice with low production cost and parameters involved therein are highly controllable.
    Type: Grant
    Filed: December 31, 2010
    Date of Patent: October 30, 2012
    Assignee: Zhongtian Technology Fibre Optics Co., Ltd.
    Inventors: Jiping Xue, Chi Xue, Yichun Shen, Zhaozhang Zhu, Qunshan Xue, Weixing Zhuang, Shanshan Cao, Yali Chen, Ming Liu
  • Publication number: 20110094268
    Abstract: A method for producing a single-mode fiber for submarine cables including washing and flame polishing of a preform, fiber drawing, coating with a first coating layer and curing therein using an UV-curing device, coating with a second coating layer and curing therein using the UV-curing device, fiber selection with a 2% screening strain, and testing the properties of the fiber. The fiber has a high strength and long coiling length exceeding 100 km and the method is easy to practice with low production cost and parameters involved therein are highly controllable.
    Type: Application
    Filed: December 31, 2010
    Publication date: April 28, 2011
    Inventors: Jiping XUE, Chi XUE, Yichun SHEN, Zhaozhang ZHU, Qunshan XUE, Weixing ZHUANG, Shanshan CAO, Yali CHEN, Ming LIU
  • Patent number: 6423552
    Abstract: The present invention relates to a method for the preparation of compound of microarray chips, especially the method by repeatedly impressing reagents at fixed locations on a substrate to synthesize said chips; and also realtes to a compound microarray chips produced according to said method.
    Type: Grant
    Filed: January 9, 2001
    Date of Patent: July 23, 2002
    Assignee: Zuhong Lu
    Inventors: Zuhong Lu, Liapang Zhang, Jianmin Ma, Chunxiang Xu, Yali Chen