Patents by Inventor Yali LU

Yali LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heavy-chain antibodies (VHHs) against claudin 18A2 and use thereof
    Patent number: 11560427
    Abstract: The present disclosure relates to the field of biology, in particular, to an anti-CLD18A2 VHH. The present disclosure provides an anti-CLD18A2 VHH. A complementarity determining region (CDR) of the anti-CLD18A2 VHH includes CDR1-CDR3 having amino acid sequences as shown below: CDR1 having an amino acid sequence represented by one of SEQ ID NO. 4-11, CDR2 having an amino acid sequence represented by one of SEQ ID NO. 19-26, and CDR3 having an amino acid sequence represented by one of SEQ ID NO.33-39. The anti-CLD18A2 VHH of the present disclosure can specifically bind to the epitope on CLD18A2, and the corresponding fusion protein thereof has good specificity and affinity for CLD18A2, and has a noticeable tumor suppression effect.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: January 24, 2023
    Assignee: ZHEJIANG DOER BIOLOGICS CO., LTD.
    Inventors: Gaofeng Yao, Yali Lu, Zhenxing Zhou, Yilin Fang, Li'na Zhu, Changkui Li, Hongta Zhang, Xiaofang Wen, Jiali Dong, Yanshan Huang
  • ANTI-CLD18A2 NANOBODY AND USE THEREOF
    Publication number: 20220259303
    Abstract: The present disclosure relates to the field of biology, in particular, to an anti-CLD18A2 VHH. The present disclosure provides an anti-CLD18A2 VHH. A complementarity determining region (CDR) of the anti-CLD18A2 VHH includes CDR1-CDR3 having amino acid sequences as shown below: CDR1 having an amino acid sequence represented by one of SEQ ID NO. 4-11, CDR2 having an amino acid sequence represented by one of SEQ ID NO. 19-26, and CDR3 having an amino acid sequence represented by one of SEQ ID NO.33-39. The anti-CLD18A2 VHH of the present disclosure can specifically bind to the epitope on CLD18A2, and the corresponding fusion protein thereof has good specificity and affinity for CLD18A2, and has a noticeable tumor suppression effect.
    Type: Application
    Filed: December 6, 2019
    Publication date: August 18, 2022
    Applicant: ZHEJIANG DOER BIOLOGICS CORPORATION
    Inventors: Gaofeng YAO, Yali LU, Zhenxing ZHOU, Yilin FANG, Li'na ZHU, Changkui LI, Hongta ZHANG, Xiaofang WEN, Jiali DONG, Yanshan HUANG
  • Headphone
    Patent number: D1135867
    Type: Grant
    Filed: March 17, 2025
    Date of Patent: July 21, 2026
    Assignee: JRD COMMUNICATION (SHENZHEN) LTD.
    Inventors: Yali Lu, Fuqiang Ye, Yan Zhu, Liangjian Chen
  • Mobile phone
    Patent number: D1142285
    Type: Grant
    Filed: March 19, 2025
    Date of Patent: August 18, 2026
    Assignee: JRD COMMUNICATION (SHENZHEN) LTD.
    Inventors: Yali Lu, Yan Zhu, Fuqiang Ye, Liangjian Chen, Wei Yang