Patents by Inventor Yalu Wen

Yalu Wen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microarray-based gene copy number analyses
    Patent number: 8412465
    Abstract: This invention contemplates an accurate and efficient estimation of gene copy number using oligonucleotide microarrays. The method integrates gene copy number data obtained from perfect match and mismatch probe sequence structure intensities and probe binding affinities. In one embodiment, an accurate determination of single nucleotide polymorphisms (SNPs) sequences is obtained. In another embodiment, an accurate detection and determination of DNA copy number alteration is obtained. In another embodiment, an accurate estimation for RNA gene expression is obtained.
    Type: Grant
    Filed: April 7, 2010
    Date of Patent: April 2, 2013
    Assignee: Board of Trustees of Michigan State University
    Inventors: Wenjiang Fu, Yalu Wen, Ming Li
  • Microarray-Based Gene Copy Number Analyses
    Publication number: 20100222225
    Abstract: This invention contemplates an accurate and efficient estimation of gene copy number using oligonucleotide microarrays. The method integrates gene copy number data obtained from perfect match and mismatch probe sequence structure intensities and probe binding affinities. In one embodiment, an accurate determination of single nucleotide polymorphisms (SNPs) sequences is obtained. In another embodiment, an accurate detection and determination of DNA copy number alteration is obtained. In another embodiment, an accurate estimation for RNA gene expression is obtained.
    Type: Application
    Filed: April 7, 2010
    Publication date: September 2, 2010
    Inventors: Wenjiang Fu, Yalu Wen, Ming Li