Abstract: An implantable device for monitoring a physiological status and administering drugs therefor includes at least one drug reservoir for containing at least one drug solution; a delivering member coupled to the at least one drug reservoir for operably delivering the at least one drug solution from the at least one drug reservoir to the living subject; a sensor member for measuring physiological parameters of a living subject so as to monitor a physiological status of the living subject; a wireless communication system for wireless data transmission; a power management system for wireless power harvesting; and a controller coupled to the power management system, the wireless communication system, the sensor member and the delivering member for wireless data transmission and power harvesting; obtaining the physiological status of the living subject, and controlling operations of the delivering member based on the physiological status of the living subject.

Abstract: The present disclosure relates to Solid Forms of 3-(5-Fluorobenzofuran-3-yl)-4 (5-methyl-5H-[1,3] dioxolo [4,5-f] indol-7-yl) pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl) pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: Provided are fused ring compounds of Formula (I), Formula (II), or Formula (III), as further detailed herein, which are used for the inhibition of Ras proteins, as well as compositions comprising these compounds and methods treatment by their administration.

Abstract: Provided are fused ring compounds of Formula (I), Formula (II), or Formula (III), as further detailed herein, which are used for the inhibition of Ras proteins, as well as compositions comprising these compounds and methods treatment by their administration.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Abstract: Deeply rechargeable battery systems and methods, where a core/shell nanoscale structure provides deeply rechargeable anodes that overcome intrinsic limitations of conventional battery materials that involve soluble intermediates or insulating discharge products. The deeply rechargeable battery systems and methods simultaneously overcome the dilemmas of passivation and dissolution. An ion-sieving concept is applied to a Zn anode that confines larger zincate ions and allows smaller hydroxide ions to permeate, can limit/prevent ZnO dissolution and electrode shape change.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl) pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo [4,5-f]indol-7-yl) pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present disclosure relates to solid forms of 3-(5-Fluorobenzofuran-3-yl)-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)pyrrole-2,5-dione, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof in treating disease.

Abstract: The present invention relates to certain amido-benzyl sulfoxide and sulfone compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Abstract: Provided are amido spirocyclic amide and sulfonamide compounds, pharmaceutical compositions comprising such compounds, and methods of treatment using such compounds.

Abstract: The present disclosure discloses a direct-link quality monitoring method, communications device, and system, where the method includes: determining, by a local device after establishing a neighbor relationship with a peer device, whether a quantity of neighbors of the local device is the same as a quantity of neighbors of the peer device; if the quantity of neighbors of the local device is different from the quantity of neighbors of the peer device, electing a device, either the local device or the peer device, with a larger quantity of neighbors as a measurement control point MCP of a direct link between the local device and the peer device; and executing a corresponding monitoring operation according to whether the local device is the MCP of the direct link, so as to monitor quality of the direct link together with the peer device.