Abstract: A lower surface of the printing platform is provided with a displacement device, and the displacement device is used to rotate the printing platform horizontally and adjust a pitch angle of the printing platform. The additive device is located above the printing platform and is connected to one end of the robotic arm, and the additive device is provided with a pressing roller. The robotic arm includes rotating joints used to drive the additive device to print and melt a fiber tow on the printing platform according to a predetermined path. The fiber pulling device is disposed on the printing platform to grab the reinforced fiber and make it cross-weave with the horizontally printed fiber tow on the horizontal plane. When working, the pressing roller is always perpendicular to the printing platform to press the melted fiber tow and the reinforced fiber cross-woven with the fiber tow.

Abstract: The present application relates to the technical field of battery manufacturing, and relates to an alternate film pasting device for hard-case secondary batteries.

Abstract: Extracellular vesicles (EVs) from human induced pluripotent stem cells (hiPSCs) may be produced by forming 3-D brain organoids of the hiPSCs in a dynamic bioreactor and collecting the EVs from the bioreactor. The EVs may be used for treating ischemic conditions.

Abstract: This disclosure provides a container wallboard module and a container. The container wallboard module includes a wallboard body and two side columns. The side columns deviate from two ends of the wallboard body in a length direction. The wallboard body is provided with assembly holes for detachable connection with other wallboard modules. The side column includes a column riser body and two connecting ends respectively formed at upper and lower ends of the column riser body. The connecting ends protrude from the column riser body in a front-back direction, and the connecting end is provided with a connecting hole for detachable connection with other wallboard modules. The container includes two side wall modules, a roof panel module, a bottom plate module, a front wall module and a rear wall module, all of which are detachably connected. The side columns, a top gusset and a bottom gusset form a column frame.

Abstract: A biochar is produced by co-pyrolysing an aquatic plant enriched with heavy metals with a clay mineral, and the aquatic plants themselves have high enrichment and adsorb heavy metals in contaminated water; heavy metals are in situ adsorbed, and are coated or enriched in the biochar, therefore extending the migration time of heavy metals, which are also very stable; attapulgite and montmorillonite as clay minerals are loaded in the biochar during the preparing process; heavy metals contained in the biochar play a catalytic role, and synergy with activated attapulgite, therefore increasing the reliability of the biochar, and effectively reducing the ecological effectiveness and potential risk of heavy metals in the biochar.

Abstract: A silicone pressure sensitive adhesive composition is curable to form a silicone pressure sensitive adhesive. The silicone pressure sensitive adhesive composition can be coated on a substrate and cured to form a topside protective film. The topside protective film can be used to protect an anti-fingerprint hard coating in a screen protective film on cover glass for a display device, such as a smartphone.

Abstract: The present invention relates to Atrial Natriuretic Peptide (ANP) polypeptides and methods of treatment with ANP polypeptides.

Abstract: Disclosed are a pyrimidine-fused cyclic compound having an inhibitory effect on KRAS gene mutation, or a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use thereof in the preparation of a drug for treating cancer.

Abstract: The present invention relates to Map4K1 inhibitors of formula (I) (I), wherein A, E, G, Q, R1, R2 and R4 have the same meaning as defined in the description, to pharmaceutical compositions and combinations comprising the compounds according to the invention, and to the prophylactic and therapeutic use of the inventive compounds, respectively to the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular for neoplastic disorders, respectively cancer or conditions with dysregulated immune responses or other disorders associated with aberrant MAP4K1 signaling, as a sole agent or in combination with other active ingredients.

Abstract: An electrolysis system is provided in some embodiments of the present disclosure, including an anode reaction chamber, a cathode reaction chamber and a spacer. The anode reaction chamber includes an anode reaction solution and an anode immersed in the anode reaction solution, in which the anode reaction solution includes an iodide ion, and a material of the anode includes a carbon material. The cathode reaction chamber includes a cathode reaction solution and a cathode immersed in the cathode reaction solution, in which the cathode reaction solution includes a hydrogen ion. The spacer separates the anode reaction chamber and the cathode reaction chamber, in which the spacer allows a cation or an anion to pass through, so that the anode reaction chamber and the cathode reaction chamber are electrically connected to each other.

Abstract: An example method of diagnosing remote sites of a distributed container orchestration system includes: receiving, at a management cluster, definition of a test suite custom resource; detecting, by a test controller agent in a cluster of the remote sites, a diagnosis object in the management cluster created in response to the test suite custom resource; deploying, by the test controller agent in response to the diagnosis object, a first pod in the cluster; deploying, by the first pod, a second pod in a server of a first remote site of the remote sites; checking, by the second pod, configuration of the server that includes an additional pod executing alongside the second pod, at least one virtual machine (VM) in which the second pod and the additional pod execute, a hypervisor configured to support the at least one VM, and a hardware platform on which the hypervisor executes; and returning test data from the second pod to the first pod, the test data including results of the step of checking the configuration o

Abstract: Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are chemically modified to increase bioavailability and activity, e.g., so that the compounds prevent adhesion and sickling of red blood cells (RBCs).

Abstract: Disclosed in the present invention is a nanobody, comprising a heavy chain variable region containing CDR1, CDR2 and/or CDR3, and having the function of recognizing and binding to BCMA. Reference can be made to the text for specific CDR sequences. Also disclosed in the present invention are a BCMA binding molecule, a composition comprising the nanobody or BCMA binding molecule, a BCMA detection agent, and an application of the nanobody, the BCMA binding molecule, or the composition in preparation of a drug for treating a BCMA related disease. The nanobody, BCMA binding molecule, and composition in the present invention can recognize and bind to BCMA, and have potential utility for treatment of BCMA related diseases.

Abstract: Disclosed is an underwater robot for a mine flooding rescue, including a starting unit configured to control the implementation of a whole rescue action; a drive unit connected with the starting unit and configured to provide a robot with power to move; and an execution unit connected with the drive unit and configured to salvage underwater life sources.

Abstract: Disclosed are an 8-(picolinamide) substituted coumarin compound, and a preparation method therefor and the use thereof, wherein the structure of the 8-(picolinamide) substituted coumarin compound is represented by formula (I), and a ring A is independently selected from a group composed of phenyl, naphthyl and a 5-14 membered aromatic heterocyclyl. The 8-(picolinamide) substituted coumarin compound disclosed in the present application is of a brand-new compound structure and has a strong SIRT2 inhibitory activity, wherein the in-vitro SIRT2 inhibitory activity IC50 of 18 compounds reaches a micromolar level, and the 8-(picolinamide) substituted coumarin compound has a significant protective effect on neuroma cells. Therefore, the compound can be widely used for preparing drugs for treating and/or preventing diseases or conditions related to excessive SIRT2 activity or overexpression of SIRT2, or preparing drugs for treating and/or preventing Parkinsons disease, metabolic diseases and tumors.

Abstract: A water boiler with dual heating functionality includes: a hot water tank having an upper section and a lower section; the upper section is narrower than the lower section; the hot water tank comprises an instantaneous heating portion, and a storage heating section; an instantaneous heating pipe arranged within the instantaneous heating portion; a storage heating pipe arranged within the storage heating portion; a water inlet component in communication with a bottom of the hot water tank; a water intake structure in communication with a pressurized water source and the water inlet component; a hot water outlet pipe connected to a top of the hot water tank.

Abstract: Provided is a method for solving radar ambiguity and occlusion based on an orthogonal two-phase coded signal. The method includes: generating and optimizing an orthogonal two-phase coded signal set by means of a walsh matrix and a genetic algorithm, and alternatively, obtaining an orthogonal two-phase coded signal set through an exhaustive method, depending on a chip length; determining the radar period and the number m of transmission pulses in a period according to the radar farthest detection range and the pulse repetition interval (PRI), and selecting m signals from the orthogonal two-phase coded signal set, to constitute a group of orthogonal two-phase coded pulse signals; and accumulating echoes of transmitted pulse signals, to generate an echo matrix, performing frequency domain pulse compression, to obtain a processed new matrix, and performing moving target detection on the matrix.

Abstract: The present disclosure provides an article. In an embodiment, the article includes (A) a top layer composed of a composition composed of (i) from 51 wt % to 90 wt % of a propylene-based polymer, and (ii) from 10 wt % to 49 wt % of an ethylene/octene multi-block copolymer having hard segments and soft segments. The ethylene/octene multi-block copolymer has a soft segment melt temperature (SS-Tm) less than 2° C. The article also includes (B) a bottom layer composed of a textile.

Abstract: A method is provided. The method comprises: obtaining, by a processing system and using a set of rotation electrodes that interact with the knob interface, first resulting signals and second resulting signals; determining, by the processing system, an initial state of the knob interface using the first resulting signals and the second resulting signals; obtaining, by the processing system and using the set of rotation electrodes, third resulting signals indicating a first rotational state of the knob interface, based at least in part on the knob interface being rotated from the initial state to the first rotational state; determining, by the processing system, the rotational direction of the knob interface using the first resulting signals, the second resulting signals, and the third resulting signals; and adjusting, by the processing system, a setting using the determined rotational direction.

Abstract: In a battery monitoring circuit, a bypath circuit includes a first terminal coupled to a positive terminal of a battery cell and a second terminal coupled to a negative terminal of the battery cell. A resistive component includes a third terminal coupled to the second terminal of the bypath circuit, and includes a fourth terminal coupled to a reference signal source that controls the resistive component to generate a reference voltage. A controller controls turning on and off the bypath circuit and the reference signal source, monitors a status of the battery cell when the bypath circuit and the reference signal source are off, senses a test voltage between the first terminal and the fourth terminal when the bypath circuit and the reference signal source are on, and generates a status signal indicative of an operating status of the battery monitoring circuit according to the test voltage.