Abstract: Improved methods and systems for active surveillance are generally described. For example, methods comprising subjecting the blood sample of the subject to one or more immunoassays that measure levels of kallikrein markers comprising free prostate specific antigen (fPSA), intact prostate specific antigen (iPSA), total prostate specific antigen (tPSA) and human kallikrein 2 (hK2); and determining the probability that a prostate tissue biopsy obtained from the subject would contain detectable aggressive prostate cancer using a logistic regression model with aggressive prostate cancer as the outcome are described.

Abstract: An industrialized protein production system using carbon-containing industrial gas includes a bacteria preparation system, a raw gas purification system, a water purification system, a bacteria separation system and a protein preparation system, wherein the bacteria preparation system is respectively communicated with the raw gas purification system, the water purification system and the bacteria separation system, and the protein preparation system is communicated with the bacteria separation system. By purifying the raw gas and the raw water and removing impurities from the raw gas and competing bacteria in the raw water, excellent raw materials and environment are provided for bacterial reproduction, which enable the raw gas to have high-efficiency fermentation, thereby increasing the yield of proteins.

Abstract: The present disclosure provides certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro- 1H-cyclopenta[cd]inden-7-yl)oxy)-benzonitrile (Compound 1) and certain polymorphs thereof. Also provided are pharmaceutical compositions comprising a crystalline polymorph form of Compound 1 and processes for preparing such polymorph forms.

Abstract: A reset switch power supply on-off control circuit and system, used for reset switches. The reset switch power supply on-off control circuit includes a reset switch control circuit connected with a reset switch and is configured to collect a status of the reset switch and output a status signal and a first control signal; an MOS switch circuit connected with the reset switch control circuit and configured to receive the first control signal from the reset switch control circuit; and a main control chip connected with the reset switch control circuit and is configured to acquire the status signal from the reset switch control circuit and output a second control signal to the reset switch control circuit.

Abstract: The present disclosure provides certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)-benzonitrile (Compound 1) and certain polymorphs thereof. Also provided are pharmaceutical compositions comprising a crystalline polymorph form of Compound 1 and processes for preparing such polymorph forms.

Abstract: Aspects of the disclosure relate to improved methods and systems for active surveillance of subject having non-aggressive prostate cancer.

Abstract: A reset switch power supply on-off control circuit and system, used for reset switches. The reset switch power supply on-off control circuit includes a reset switch control circuit connected with a reset switch and is configured to collect a status of the reset switch and output a status signal and a first control signal; an MOS switch circuit connected with the reset switch control circuit and configured to receive the first control signal from the reset switch control circuit; and a main control chip connected with the reset switch control circuit and is configured to acquire the status signal from the reset switch control circuit and output a second control signal to the reset switch control circuit.

Abstract: An industrialized protein production system using carbon-containing industrial gas includes a bacteria preparation system, a raw gas purification system, a water purification system, a bacteria separation system and a protein preparation system, wherein the bacteria preparation system is respectively communicated with the raw gas purification system, the water purification system and the bacteria separation system, and the protein preparation system is communicated with the bacteria separation system. By purifying the raw gas and the raw water and removing impurities from the raw gas and competing bacteria in the raw water, excellent raw materials and environment are provided for bacterial reproduction, which enable the raw gas to have high-efficiency fermentation, thereby increasing the yield of proteins.

Abstract: The present invention provides a method and system for detecting vulnerabilities of NODE.JS components. The method includes the following steps: collecting first basic vulnerability information from a NODE.JS vulnerability database; parsing a package.json file to obtain key information of a NODE.JS component; and extracting first target, vulnerability information from the first basic vulnerability information according to the key information of the NODE.JS component. With the method for detecting vulnerabilities of NODE.JS components provided by the present invention, first basic vulnerability information can be collected from a NODE.JS vulnerability database, and possible vulnerability information of a NODE.JS component may be quickly obtained. A package.json file is a file in the NODE.JS component. When parsing the package.json file, the key information of the to-be-detected NODE.JS component can be obtained, thereby contributing to data call, and arrangement.

Abstract: The present disclosure discloses a method for modulating a switch of a converter. The method is applicable to a topological structure of a multiphase stacked interleaved buck converter, and includes: acquiring charge-discharge state information in the topological structure, wherein the charge-discharge state information comprises at least a first charge-discharge state of any one phase primary loop, a second charge-discharge state of a secondary loop corresponding to the any one phase primary loop, a third charge-discharge state of another primary loop, and a fourth charge-discharge state of another secondary loop; and adjusting, based on the first charge-discharge state, a closed state of a switch disposed on a bridge arm connected to the any one phase primary loop, and adjusting, based on the second charge-discharge state and the third charge-discharge state, a closed state of a switch disposed on another bridge arm.

Abstract: The present disclosure provides certain processes of making 3-fluoro-5-(((1S,2aR)-1,3,3,4,4-pentafluoro-2a-hydroxy-2,2a,3,4-tetrahydro-1H-cyclopenta[cd]inden-7-yl)oxy)-benzonitrile (Compound 1) and certain polymorphs thereof. Also provided are pharmaceutical compositions comprising a crystalline polymorph form of Compound 1 and processes for preparing such polymorph forms.

Abstract: Aspects of the disclosure relate to improved methods and systems for active surveillance of subject having non-aggressive prostate cancer.

Abstract: The application provides a determination method and a determination apparatus for conversion efficiency of hydrogen production by wind-solar hybrid electrolysis of water. The method includes that: first test data of a target factor influencing the conversion efficiency of hydrogen production by wind-solar hybrid electrolysis of water is acquired in real time; a neural network model of the conversion efficiency is established; and the conversion efficiency is determined according to the neural network model and the first test data.

Abstract: Aspects of the disclosure relate to improved methods and systems for predicting prostate cancer pathology associated with adverse outcomes in patients determined to a primary Gleason Grade of 3.