Abstract: A conjugate provided. The conjugate is a compound represented by Formula (I), or the conjugate is a stereoisomer, tautomer, homologue, solvate, metabolite, pharmaceutically acceptable salt, or prodrug of the compound represented by Formula (I): where A is a linker, and B is a dihydrofolate reductase inhibitor; R1, R2, R3, R4, and R5 are independently selected from H or C1-6 alkyl; and n1, n2, and n3 are each an integer selected from 0 to 6.

Abstract: To mitigate undesirable outcomes due to crosstalk in an ambient light sensor reading resulting from light emission from an electronic display, statistics may be gathered to determine and compensate for the crosstalk. For example, the ambient light sensor may detect ambient light levels while the electronic display is temporarily paused to reduce or eliminate crosstalk between the light produced by the electronic display and the ambient light sensor. However, the ambient light sensor may retain charge from a previous light emission, creating back-emission crosstalk. The ratio of back-emission to front-emission (e.g., present light emission) may not be linear, and the degree of nonlinearity may vary with pixel value, color component, display brightness, temperature, and so on. As the ambient light sensor is affected by back-emission, compensation for the nonlinearity between the front-emission and the back-emission may be obtained to estimate the crosstalk induced on the ambient light sensor.

Abstract: To mitigate undesirable outcomes due to crosstalk in an ambient light sensor reading resulting from light emission from an electronic display, statistics may be gathered to determine and compensate for the crosstalk. For example, the ambient light sensor may detect ambient light levels while the electronic display is temporarily paused to reduce or eliminate crosstalk between the light produced by the electronic display and the ambient light sensor. However, the ambient light sensor may retain charge from a previous light emission, creating back-emission crosstalk. The ratio of back-emission to front-emission (e.g., present light emission) may not be linear, and the degree of nonlinearity may vary with pixel value, color component, display brightness, temperature, and so on. As the ambient light sensor is affected by back-emission, compensation for the nonlinearity between the front-emission and the back-emission may be obtained to estimate the crosstalk induced on the ambient light sensor.

Abstract: A conjugate provided. The conjugate is a compound represented by Formula (I), or the conjugate is a stereoisomer, tautomer, homologue, solvate, metabolite, pharmaceutically acceptable salt, or prodrug of the compound represented by Formula (I): where A is a linker, and B is a dihydrofolate reductase inhibitor; R1, R2, R3, R4, and R5 are independently selected from H or C1-6 alkyl; and n1, n2, and n3 are each an integer selected from 0 to 6.

Abstract: A color ambient light sensor may gather ambient light measurements during operation of an electronic device. The color ambient light sensor may have a color ambient light detector and an adjustable neutral density filter. The electronic device may have components such as a camera and display that are adjusted using ambient light information from the color ambient light sensor. The display may have a display cover layer. Pixels in an active area of the display may display images through the display cover layer. An inactive area of the display may have an opaque masking layer on an interior surface of the display cover layer. An opening in the opaque masking layer may form an ambient light sensor window for the color ambient light sensor. The adjustable neutral density filter may be interposed between the color ambient light detector and the ambient light sensor window.

Abstract: A color ambient light sensor may gather ambient light measurements during operation of an electronic device. The color ambient light sensor may have a color ambient light detector and an adjustable neutral density filter. The electronic device may have components such as a camera and display that are adjusted using ambient light information from the color ambient light sensor. The display may have a display cover layer. Pixels in an active area of the display may display images through the display cover layer. An inactive area of the display may have an opaque masking layer on an interior surface of the display cover layer. An opening in the opaque masking layer may form an ambient light sensor window for the color ambient light sensor. The adjustable neutral density filter may be interposed between the color ambient light detector and the ambient light sensor window.

Abstract: A system for quantitative detection and analysis of the interactions of molecules with molecular receptors on the surfaces of biological cells based on detecting a mechanical deformation in the membrane of a cell associated with the molecular interactions, which works for both large and small molecules. The mechanical deformation can be detected with high precision in real time from an optical image of the cell with a differential detection method. The system can be also used to detect the electrical activities, such as ion channel opening and closing, as well as action potential propagation in neuronal cells.

Abstract: A system for quantitative detection and analysis of the interactions of molecules with molecular receptors on the surfaces of biological cells based on detecting a mechanical deformation in the membrane of a cell associated with the molecular interactions, which works for both large and small molecules. The mechanical deformation can be detected with high precision in real time from an optical image of the cell with a differential detection method. The system can be also used to detect the electrical activities, such as ion channel opening and closing, as well as action potential propagation in neuronal cells.

Abstract: A system for quantitative detection and analysis of the interactions of molecules with molecular receptors on the surfaces of biological cells based on detecting a mechanical deformation in the membrane of a cell associated with the molecular interactions, which works for both large and small molecules. The mechanical deformation can be detected with high precision in real time from an optical image of the cell with a differential detection method. The system can be also used to detect the electrical activities, such as ion channel opening and closing, as well as action potential propagation in neuronal cells.

Abstract: Methods for depositing extremely low resistivity tungsten in semiconductor processing are disclosed herein. Methods involve annealing the substrate at various times during the tungsten deposition process to achieve uniform tungsten layers with substantially lower resistivity.

Abstract: Methods for depositing extremely low resistivity tungsten in semiconductor processing are disclosed herein. Methods involve annealing the substrate at various times during the tungsten deposition process to achieve uniform tungsten layers with substantially lower resistivity.

Abstract: A system for quantitative detection and analysis of the interactions of molecules with molecular receptors on the surfaces of biological cells based on detecting a mechanical deformation in the membrane of a cell associated with the molecular interactions, which works for both large and small molecules. The mechanical deformation can be detected with high precision in real time from an optical image of the cell with a differential detection method. The system can be also used to detect the electrical activities, such as ion channel opening and closing, as well as action potential propagation in neuronal cells.

Abstract: Methods for depositing extremely low resistivity tungsten in semiconductor processing are disclosed herein. Methods involve annealing the substrate at various times during the tungsten deposition process to achieve uniform tungsten layers with substantially lower resistivity.

Abstract: A technique and apparatus for cleaning the underside of a pedestal in a single- or multi-station semiconductor processing chamber or tool are provided. Also provided is an integrated vacuum foreline manifold having symmetric flow path lengths that may be used in multi-station semiconductor processing chamber or tool.

Abstract: Methods of producing low resistivity tungsten bulk layers having low roughness and associated apparatus are provided. According to various embodiments, the methods involve CVD deposition of tungsten at high pressures and/or high temperatures. In some embodiments, the CVD deposition occurs in the presence of alternating nitrogen gas pulses, such that alternating portions of the film are deposited by CVD in the absence of nitrogen and in the presence of nitrogen.

Abstract: Methods of producing low resistivity tungsten bulk layers having low roughness and associated apparatus are provided. According to various embodiments, the methods involve CVD deposition of tungsten at high pressures and/or high temperatures. In some embodiments, the CVD deposition occurs in the presence of alternating nitrogen gas pulses, such that alternating portions of the film are deposited by CVD in the absence of nitrogen and in the presence of nitrogen.

Abstract: Provided are methods and related apparatus for removing tungsten film from a station of a single-station or multi-station chamber and station component surfaces between tungsten deposition processes. In some embodiments, the methods can involve introducing an inert gas flow upstream of a gas inlet to a station and downstream of a remote plasma generator that provides activated cleaning species. In some embodiments, the methods can involve modulating inert gas flow during various stages of a cleaning process. In some embodiments, the methods can involve manipulating positions of a substrate carrier ring during various stages of the cleaning process. Also in some embodiments, the methods can involve differentially modulating the amounts of inert gas introduced to stations of a multi-station chamber. The methods can provide improved clean uniformity, reduced over-etch, and increased throughput due to shorter cleaning time.