Abstract: The present invention relates to methods for the selective expansion of ?? T-cell population(s), compositions and admixtures thereof and methods for using the same as a therapeutic. Non-engineered and engineered, enriched ?? T-cell populations of the disclosure are useful in the treatment of various cancers, infectious diseases, and immune disorders.

Abstract: The present disclosure comprises methods and compositions for scalable production of extracellular vesicles (EVs) from human blood vessel organoids using vertical-wheel bioreactors, yielding EVs with defined lipidomic profiles and demonstrated therapeutic potential for cell-free therapies.

Abstract: A method and a device for rapidly constructing field signature method databases, and the method includes: S1—simulation requirements analysis, including calculating electric field distribution information of monitored components containing pitting corrosion; S2—simulation parameter settings, establishing simulation calculation models of the monitored components; S3—simulation calculation: based on set simulation parameters, calculating electric field distribution information of models with and without pitting corrosion under all single parameters; S4—extracting potential information from simulation models and constructing a potential matrix: based on preset electrode matrix parameters, constructing an electric field data extraction coordinate matrix and extracting potential information corresponding to each coordinate; S5—data post-processing: based on the potential matrix, constructing an initial potential difference matrix and a collected potential difference matrix respectively, and then calculating an FC

Abstract: A method and an apparatus of processing an image, an interactive device, an electronic device, a storage medium, and a computer program product are provided. The method of processing the image includes: acquiring N1 two-dimensional key points from a face image of an object, wherein a plurality of facial regions in the face image respectively correspond to a plurality of mapping models; mapping the N1 two-dimensional key points into N2 two-dimensional key points by mapping the two-dimensional key points within each facial region based on the mapping model corresponding to the facial region, where N2 is not equal to N1; performing an iterative optimization on an initial three-dimensional face template by using the N2 two-dimensional key points to obtain a target three-dimensional face template; and determining a head pose of the object according to a corresponding relationship between the face image and the target three-dimensional face template.

Abstract: An aspect of the present disclosure features a control module for a LLC converter including a PFC circuit and a LLC circuit. A bulk capacitor is included in the LLC converter between the PFC circuit and the LLC circuit. The control module includes a secondary side controller coupled to an output of the LLC circuit and configured to receive an output current of the LLC circuit. The control module also includes an optical coupling circuit coupled to the secondary side controller. The control module also includes a primary side controller coupled to the optical coupling circuit and the PFC circuit. The secondary side controller generates a PWM signal according to a fluctuation of the output current and outputs the PWM signal to the optical coupling circuit, and the optical coupling circuit converting the PWM signal to an analog signal and outputs the analog signal to the primary side controller.

Abstract: A data transmission method, an apparatus, and a system are provided. In the method, there is at least one tunnel between an access network device and a terminal device, the tunnel includes at least one stream, and the at least one stream is used to transmit data. The access network device may send mapping information to the terminal device, and then data transmission may be performed between the access network device and the terminal device based on the mapping information, to implement mapping between data transmitted through the tunnel or a stream on the tunnel and a QoS flow, thereby implementing differentiated transmission.

Abstract: Embodiments of the present application disclose a boron-containing organic compound and applications thereof. The boron-containing organic compound is shown in the general formula (I): The hole-transporting group of the pentyl group is beneficial to improve the hole-transporting performance of the compound on the one hand, and on the other hand, it can enhance the resonance performance of the molecule, so that when the boron-containing organic compound is applied to an organic light-emitting device, it can effectively improve its light extraction efficiency. Meanwhile, the cyclopentyl group can effectively increase the distance between molecules, and can inhibit the exciton quenching caused by the accumulation between molecules. When this boron-containing organic compound is applied to blue light materials, it can effectively improve the stability and life of the device.

Abstract: This application relates to a communication method, apparatus, and system. A first core network element obtains first BDP requirement information, where the first BDP requirement information indicates a requirement for a product of a bandwidth and a transmission delay that correspond to a first service. The first core network element sends first BDP information to an access network device, where the first BDP information is determined based on the first BDP requirement information, and the first BDP information is used by the access network device to schedule a resource for a terminal device based on the first BDP information. In embodiments of this application, parameters such as a bandwidth and a delay may be considered in combination, to comprehensively ensure network performance.

Abstract: Provided is a method for reducing nitrogen and phosphorus emissions in strawberry cultivation to mitigate continuous cropping obstacles in greenhouses, which includes: S1, after the current season's strawberries are harvested and before the next season's strawberries are planted, applying a biological disinfectant and a nutrient agent to the soil and cover with a film for high-temperature sterilization; and S2, after planting two seasons of strawberries, plowing dead branches and leaves into the soil, applying a soil conditioner, covering the soil with the film, applying base fertilizer after removing the film, sowing green manure seeds, and plowing the green manure into the soil, applying a composting agent, covering with a film to allow to ferment.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive a first activation message to activate a beam lock in an anechoic chamber (AC). The UE may transmit a first completion message that indicates completion of the beam lock in the AC. The UE may receive a request for a beam identifier (ID) that is based at least in part on the beam lock. The UE may transmit the beam ID. Numerous other aspects are described.

Abstract: A composition including modified macrophages and its use in the treatment of melanoma and pancreatic cancer. The modified macrophages have a deletion of fragile-site associated tumor suppressor (FATS) or include a small interfering RNA (siRNA) capable of silencing the FATS. The knockout or inhibition of FATS may promote the polarization of M0 macrophages into M1 macrophages and suppress the polarization of M0 macrophages into M2 macrophages. The FATS can be used as a target for the production of medications for the treatment of cancer or tumors.

Abstract: Methods, systems, and devices for wireless communications are described. A user equipment (UE) switch between carriers of a group of a carriers during uplink communications in accordance with a mapping. For example, the UE may report its capability to a base station for switching between carriers of the group, where the group includes a supplementary uplink (SUL) carrier and two or more normal uplink (NUL) carriers that are each associated with a different radio frequency band. The base station may indicate for the UE to switch to a subset of carriers of the group corresponding to a combination of radio frequency bands for transmission of an uplink message. The UE may switch to at least one carrier of the subset of carriers in accordance with a mapping that is based on the reported capability and may transmit the uplink message on the at least one carrier.

Abstract: Provided are a biphenyl compound, a pharmaceutical composition, a method for preparing same, and use thereof. The biphenyl compound has a structure represented by formula I. The provided biphenyl compound can have relatively good binding to multiple target proteins, has relatively good bioavailability, and can be used for preparing drugs for preventing or treating tumors, autoimmune diseases, inflammatory diseases, and neurodegenerative diseases or anti-aging drugs.

Abstract: A novel material for producing auxetic foams is disclosed. The material comprises a multiphase, multicomponent polymer foam with a filler polymer having a carefully selected glass transition temperature. Novel methods for producing auxetic foams from the material are also disclosed that consistently, reliably and quickly produce auxetic polyurethane foam at about room temperature (25° C.). This technology overcomes challenging issues in the large-scale production of auxetic PU foams, such as unfavorable heat-transmission problem and harmful organic solvents.

Abstract: Systems and techniques are described herein for wireless communication. For example, a computing device can transmit a message including location data and route data associated with the apparatus to request adjustment of a route of one or more aerial vehicles. The computing device can receive a response to the message from the one or more aerial vehicles, the response indicating acceptance of the message to adjust the route of the one or more aerial vehicles. The computing device can adjust at least one of the route data of the apparatus based on the response or cause adjustment of the route of the one or more aerial vehicles based on the message.

Abstract: Methods and systems for detecting opacity in the cornea using optical coherence tomography are described. Corneal reflectance is analyzed as a function of anatomic layer within the cornea, depth within a given anatomic layer, and the angle of incidence of the OCT beam on the anterior corneal surface. Also disclosed is a thresholding technique based on the percentile distribution of reflectance values from a retrospective analysis of OCT scans from normal corneas. The techniques described herein are not dependent on the specific hardware configuration of the OCT system used, and they allow the automated detection, analysis, and quantitative characterization of corneal opacities and provide insight into tissue directionality as a function of depth within specific corneal layers.

Abstract: A light-emitting diode includes an epitaxial structure, at least one via hole, a first insulation layer, a first connecting electrode, a second connecting electrode, a second insulation layer, a first pad, and a second pad. The first insulation layer includes a first insulation portion and a second insulation portion such that an upper surface of the first connecting electrode and an upper surface of the second connecting electrode are disposed on the same level so as to ensure that an upper surface of the first pad and an upper surface of the second pad are also on the same level.

Abstract: Removal of motion artifacts from photoplethysmography (PPG) signals from a PPG sensor by applying a harmonic notch filter to a PPG signal where positions of the filter notches are based on a period of an accelerometer signal received from an accelerometer sensor in a vicinity of the PPG sensor to yield a first filtered signal; determining a signal quality index (SQI) associated with the PPG signal based on the accelerometer signal; determining an estimated heart rate based on the PPG signal; and applying a harmonic comb filter to the first filtered signal to where the filter peaks are based on the estimated heart rate. The estimated heart rate may be determined according to a confidence level based on SQI. A wearable device may implement the system for removing motion artifacts from PPG signals.

Abstract: Methods and systems are provided for locating a medical device within vasculature. Methods and systems may include receiving a series of intravascular image frames captured along a portion of the vessel; extracting a plurality of longitudinal images from the series of intravascular image frames, each one of the plurality of longitudinal images sampled at a different angle. Methods and systems may include condensing each of the plurality of longitudinal images into corresponding longitudinal intensity values; averaging the longitudinal intensity values for each of the plurality of longitudinal images; deriving a series of intensity variation values based in part on the average longitudinal intensity values for each of the plurality of longitudinal images; identifying a longitudinal location along the portion of the vessel based on the series of intensity variation values; and outputting an indication of a frame of the series of intravascular image frames corresponding to the longitudinal location.

Abstract: The present disclosure provides compounds of Formula (I) and (II) or salts, enantiomers, stereoisomers, solvates, isotopically enriched analogs, prodrugs, or polymorphs thereof, and uses thereof. The present disclosure also provides pharmaceutical compositions comprising, as an active ingredient, the compounds of Formula (I) or salts, enantiomers, stereoisomers, solvates, isotopically enriched analogs, prodrugs, or polymorphs thereof, and uses thereof.