Abstract: Provided in the present application is a polypeptide and a derivative of the polypeptide or a pharmaceutically acceptable salt thereof. The present application also provides a pharmaceutical composition comprising the polypeptide or the derivative or a pharmaceutically acceptable salt thereof described in the present application, and a pharmaceutically acceptable excipient. Use of the polypeptide, the derivative of the polypeptide or a pharmaceutically acceptable salt thereof, or the composition as described above in the field of disease prevention/treatment is also provided.

Abstract: According to an example, a massive multiple-input multiple-output (mMIMO) system operable for beamforming actuation may comprise an open radio access network radio unit (O-RU) having a processing device operable to: compute one or more of a predictive channel estimate, a beamforming estimate, or an antenna calibration; compute, based on an objective function having one or more of the predictive channel estimate, the beamforming estimate, or the antenna calibration as inputs, a power level for a data stream associated with a transmitting antenna path, wherein the power level for the data stream is selected to facilitate an equal-power distribution across a plurality of transmitting antenna paths; and set the power level for the data stream associated with the transmitting antenna path.

Abstract: Systems, methods, and apparatus, including computer-readable media, for customizing delivery of information streams to user devices. In some implementations, a system provides an interface configured to create or edit information card templates for a channel configured to provide information cards based on the templates to user devices. The system receives first input through the interface that indicates content of a first information card template. The system receives second input that specifies one or more criteria for presenting an information card based on the first information card template. The system stores a record for the first information card template that indicates (i) the content indicated by the first input and (ii) one or more criteria specified by the second input. The system configures the channel to provide information cards based on the first information card template.

Abstract: Provided herein are use of a fatty acid-containing side chain in improving activity, activity selectivity, and oral availability of a polypeptide derivative, a method for achieving the use, and a polypeptide derivative modified by the side chain.

Abstract: The disclosure relates to a communication method and system for converging a 5th-Generation (5G) communication system for supporting higher data rates beyond a 4th-Generation (4G) system with a technology for Internet of Things (IoT). The disclosure applies to intelligent services based on the 5G communication technology and the IoT-related technology, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. A method performed by a network-side control node in mobile communication system is provided. The method includes acquiring information related to cooperative scheduling corresponding to a base station, determining configuration information for cooperative scheduling on traffics in overlapped beam coverage areas associated with a plurality of base stations including the base station, based on the information related to cooperative scheduling, and transmitting, to the base station, the configuration information.

Abstract: Provided herein are antibodies (or antigen binding fragments thereof) that bind to human CTLA4 (e.g., antibodies that bind to human CTLA4) and have enhanced effector functions, masked antibodies (e.g., activatable antibodies) that bind to human CTLA4, nucleic acid molecules encoding the same, pharmaceutical compositions thereof, and methods of their therapeutic use (e.g., for treatment of cancer).

Abstract: This application provides a communication method and a communication apparatus. The method indicates core network transport path switching. The method includes establishing a second transport path, and sending first request information instructing a user plane function network element to enable, when a microburst exists on a current first transport path, the established second transport path to transmit a packet of a next frame. The second transport path includes at least one transport path between a terminal device and a core network device. This method addresses transmission delay issues caused by core network bursts in microburst scenarios of media service flows, and helps prevent out-of-order arrival of data packets, thereby improving user experience.

Abstract: The present invention provides therapeutic, diagnostic, and prognostic methods for cancer. The invention provides methods of treating a cancer, methods of determining whether an individual having a cancer is likely to respond to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of predicting responsiveness of an individual having a cancer to a treatment including an immune checkpoint inhibitor (e.g., a PD-L1 axis binding antagonist), methods of selecting a therapy for an individual having a cancer, methods of providing a prognosis for an individual having a cancer, and methods of monitoring a response of an individual having a cancer, based on a blood tumor mutational burden (bTMB) score or a maximum somatic allele frequency (MSAF) from a sample (e.g., a whole blood sample, a plasma sample, a serum sample, or a combination thereof) from the individual.

Abstract: The present disclosure provides an RF front-end chip, an RF switch module, and an RF communication device. The RF front-end chip includes a logic control circuit, a switching circuit, and an amplifier module assembly that are integrated onto an integrated circuit die, where the logic control circuit is connected to the switching circuit and configured to control the switching circuit, and the switching circuit is integrated into the amplifier module assembly and precedes one or more amplifiers of the amplifier module assembly. By utilizing the RF front-end chip, the integration level of the chip can be improved, and the cost of the chip can be reduced.

Abstract: A device structure includes base semiconductor rail structures overlying a semiconductor substrate, bottom bit lines contacting a sidewall of a respective one of the base semiconductor rail structures, a two-dimensional array of lower semiconductor pillars, lower gate electrode lines overlying the bottom bit lines and laterally spaced from sidewall segments of a respective column of the lower semiconductor pillars by a lower gate dielectric layer, a two-dimensional array of upper semiconductor pillars, upper gate electrode lines overlying the lower gate electrode lines and laterally spaced from sidewall segments of a respective column of the upper semiconductor pillars by an upper gate dielectric layer, and at least one top bit line contacting top surfaces of a respective row of upper semiconductor pillars.

Abstract: An integrated circuit device includes a semiconductor die having an active layer between opposing first and second surfaces, and a thermally conductive lid on the semiconductor die. The thermally conductive lid includes a first layer of a first material on the first surface of the semiconductor die, and a second layer of a second material on the first layer opposite the first surface. The first material has a wider bandgap than the second material. The first material may be a wide-bandgap material such as diamond, and the second material may be a semiconductor material such as silicon. Related packages and fabrication methods are also discussed.

Abstract: An apparatus may include a device including a first layer having a first thermal conductivity, a second layer having a second thermal conductivity, and a third layer having a third thermal conductivity, wherein the first layer may include a substrate core material, the third layer may include a thermally conductive material, the third thermal conductivity may be greater than the first thermal conductivity, and the third thermal conductivity may be greater than the second thermal conductivity. The third layer may be located between the first layer and the second layer. The second layer may include a substrate core material. The second layer may include a semiconductor die. The second layer may include an energy storage device. The second layer may include a power delivery network. The apparatus may further include a fourth layer attached to the first layer, wherein the fourth layer may include a lamination layer.

Abstract: An apparatus may include a device including a first semiconductor die having a first thermal conductivity, a second semiconductor die having a second thermal conductivity, and a thermally conductive layer having a third thermal conductivity, the thermally conductive layer having a first side connected to the first semiconductor die and a second side connected to the second semiconductor die, wherein the third thermal conductivity may be greater than the first thermal conductivity, and the third thermal conductivity may be greater than the second thermal conductivity. The apparatus may further include a substrate, wherein the device may be at least partially embedded in the substrate. The device may further include a third semiconductor die attached to the first semiconductor die. The device may further include a third semiconductor die attached to the first semiconductor die, and a fourth semiconductor attached to the second semiconductor die.

Abstract: Techniques for automating workflow using a real-time driver activity classification model are described herein. For example, an electronic device can execute a machine learning model based at least in part on an input comprising geolocation data and motion data detected by the electronic device. The machine learning model can generate a classification indicating that a state of the electronic device with respect to motion. The electronic device can detect that the electronic device is within a threshold distance from a service address. The electronic device can detect that the state is a non-driving state. Responsive to (i) detecting that the state is a non-driving state and (ii) detecting that the electronic device is within the threshold distance from the service address, the electronic device can transition from presenting a set of driving instructions to presenting instructions for performing a service at the service address.

Abstract: A system and method, the method including determining, by a centralized user configuration function based on a core network packet delay budget (CN PDB) and a buffer duration, an allowed maximum latency of a time-sensitive network (TSN) stream transmitted between an access network device and a user plane network element, wherein the maximum latency does not exceed a difference obtained by subtracting the buffer duration from the CN PDB, sending, by the centralized user configuration function, first latency information to a centralized network configuration function, wherein the first latency information indicates the maximum latency, receiving, by the centralized user configuration function, first configuration information, wherein the first configuration information indicates a packet transmission time of the transmit end of the TSN stream, and the packet transmission time is associated with the maximum latency, and sending the first configuration information to the transmit end of the TSN stream.

Abstract: Embodiments of this application disclose a domain name system server determining method, and a request processing method, apparatus, and system, One example method includes: determining, by a session management function network element and based on a first location of user equipment, a data network access identifier (DNAI) indicating a deployment location of a first application; determining, by the session management function network element, an address of a first local domain name system server based on the DNAI; sending, by the session management function network element, the address of the first local domain name system server to a first device; and receiving, by the first device, the address of the first local domain name system server.

Abstract: A method and a device for controlling grid configuration of a flexible direct current electric power transmission system, and a computer-readable storage medium are provided. The active power reference value is modified based on the frequency deviation of the alternating current grid. The reactive power reference value is modified based on the voltage deviation of the alternating current grid. The outputted active power and the outputted reactive power are controlled based on the active power reference value and the reactive power reference value, respectively. The grid voltage is further configured and controlled through power control, so that the system is capable of self-synchronization, frequency regulation and voltage regulation. In addition, the virtual synchronous machine technology is introduced into control of the reactive power, so that the system can provide inertia support for the grid voltage amplitude.

Abstract: A local network accessing method and apparatus are provided. The local network accessing method comprises sending a trigger message to a terminal, the trigger message is for triggering the terminal to establish a session, receiving a first message from the terminal, the first message requesting to establish a first session, and the first session is for the terminal to access a target local network, determining a target network access identifier based on the first message, the target network access identifier indicating the target local network, determining a first session management function network element based on the target network access identifier, and sending the target network access identifier to the first session management function network element, the target network access identifier is for the first session management function network element to determine a target user plane function network element.

Abstract: Fiber cement composite formulations are provided herein for manufacturing fiber cement building articles via an extruder. Some embodiments include: a cementitious binder having a particle size distribution between 1 ?m and 150 ?m and including cement and at least 5% by dry weight of limestone; cellulose and polypropylene fibers; a first quantity of silica having a particle size distribution between 1 ?m and 250 ?m; microparticulate cured fiber cement material having a particle size distribution between 1 ?m and 600 ?m and comprising a second quantity of silica of the fiber cement composite formulation; a viscosity-enhancing admixture; and an air-entraining admixture. A total amount of silica in the formulation can include the first and second quantities of silica. In some embodiments, a ratio of the cement to the total amount of silica in the formulation is between 0.7 and 1.5.

Abstract: Aspects described herein relate to associating aliases with registers in an alias table for processing graphics processing unit (GPU) instructions. An aliasing instruction indicating associations between multiple alias registers and one or more alias values can be received. An alias corresponding to one of the one or more alias values for each of the multiple alias registers can be stored in the alias table and based on the aliasing instruction.