Abstract: Some embodiments of the invention provide, for a RAN (radio access network), a method of rapidly upgrading multiple machines distributed across multiple cell sites, each particular machine of the multiple machines executing one or more base station applications. The method downloads a second boot disk for each of the multiple machines at each of the multiple cell sites, the second boot disk including an upgraded version of a first boot disk currently used by each of the multiple machines. For each particular machine, the method (1) powers off the particular machine, (2) creates a copy of data stored by a data disk of the particular machine to preserve data stored currently on the data disk, (3) replaces the first boot disk of the particular machine with the second boot disk that is the upgraded version of the first boot disk, and (4) powers on the particular machine.

Abstract: The disclosure provides a method for diagnosing remote sites of a distributed container orchestration system. The method generally includes receiving a test suite custom resource defining an image to be used for a diagnosis of components of a workload cluster deployed at the remote sites, wherein the image comprises a diagnosis module and/or a user-provided plugin to be used for the diagnosis; identifying a failed component in the workload cluster; obtaining infrastructure information about the workload cluster; identifying the components of the workload cluster for diagnosis based on the failed component, the infrastructure information, and the test suite custom resource; identifying at least one diagnosis site of the remote sites where the components are running using the infrastructure information; and deploying a first pod at the at least one diagnosis site to execute the diagnosis of the one or more components.

Abstract: The disclosure provides a method for preparing a simulation system to simulate upgrade operations for a distributed container orchestration system. The method generally includes monitoring, by a simulation operator of the simulation system, for new resources generated at a management cluster in the distributed container orchestration system, based on the monitoring, discovering, by the simulation operator, a new resource generated at the management cluster specifying a version of container orchestration software supported and made available by the management cluster, and triggering, by the simulation operator, a creation of a new mock virtual machine (VM) template in the simulation system specifying the version of the container orchestration software, wherein the simulation system is configured to use the new mock VM template for simulating mock VMs in the simulation system that are compatible with the version of the container orchestration software supported and made available by the management cluster.

Abstract: An example method of propagating fault domain topology information in a distributed container orchestration system includes: receiving, at control plane software executing in a data center, the fault domain topology, which includes tags for a protection group and fault domains for remote sites in communication with the data center; deploying, by a master server of the distributed container orchestration system that executes in the data center, a node pool comprising virtual machines (VMs) executing in servers of the remote sites, the VMs being nodes of the distributed container orchestration system in which containers execute; determining, by a controller of the master server, relationships among the VMs, the servers, the protection group, and the fault domains based on state of resources maintained by the master server; and providing, by the controller, labels to the servers for associating the tags of the protection group and the fault domains to the VMs.

Abstract: An example method of diagnosing remote sites of a distributed container orchestration system includes: receiving, at a management cluster, definition of a test suite custom resource; detecting, by a test controller agent in a cluster of the remote sites, a diagnosis object in the management cluster created in response to the test suite custom resource; deploying, by the test controller agent in response to the diagnosis object, a first pod in the cluster; deploying, by the first pod, a second pod in a server of a first remote site of the remote sites; checking, by the second pod, configuration of the server that includes an additional pod executing alongside the second pod, at least one virtual machine (VM) in which the second pod and the additional pod execute, a hypervisor configured to support the at least one VM, and a hardware platform on which the hypervisor executes; and returning test data from the second pod to the first pod, the test data including results of the step of checking the configuration o

Abstract: An example method of propagating fault domain topology information in a distributed container orchestration system includes: receiving, at control plane software executing in a data center, the fault domain topology, which includes tags for a protection group and fault domains for remote sites in communication with the data center; deploying, by a master server of the distributed container orchestration system that executes in the data center, a node pool comprising virtual machines (VMs) executing in servers of the remote sites, the VMs being nodes of the distributed container orchestration system in which containers execute; determining, by a controller of the master server, relationships among the VMs, the servers, the protection group, and the fault domains based on state of resources maintained by the master server; and providing, by the controller, labels to the servers for associating the tags of the protection group and the fault domains to the VMs.

Abstract: The disclosure provides an approach for simulating a virtual environment. A method includes simulating, using a virtualization simulator, a plurality of hosts; simulating, using the virtualization simulator, a plurality of virtual computing instances (VCIs) associated with the plurality of simulated hosts, based on information obtained from a cluster application programming interface (API) provider; creating, using a virtualization simulator operator, one or more node simulator schedulers; creating, using the one or more node schedulers, a node simulator; simulating, using the node simulator, a plurality of guest operating systems (OSs) associated with the plurality of simulated VCIs; and joining the plurality of simulated guest OSs to one or more node clusters in a data center via an API server.

Abstract: An example method of updating device firmware in a distributed container orchestration system includes: receiving, at a master server executing in a data center, a definition for a firmware custom resource; obtaining, by an operator of the master server in response to the firmware custom resource, a firmware file set; providing, from the operator to a plurality of remote sites in communication with the data center, the firmware file set; and executing, by servers at the plurality of remote sites, updates of firmware for devices of the servers.

Abstract: The present disclosure provides a universal influenza virus vaccine. A composition for a universal influenza virus vaccine comprises at least two, preferably more than two, different influenza hemagglutinin (HA) derived antigens. The HA proteins from which the antigens are derived have a hypervariable region located between conserved cysteines at positions 52 and 277, and the hypervariable region is deleted in the antigens. The at least two antigens each have a similarity with HA molecules of more than one influenza serotype in excess of 60, or 70, or 80, as calculated by the emboss explorer cons program.

Abstract: This disclosure is directed to a simulation system that verifies functionality and performance of an automated telecommunication cloud platform (“TCP”) which is used to configure hosts of cell sites and a mobile core of a 5G cellular network. The mock hosts are created with a required virtualization platform inventory of objects for implementing a 5G cellular network and registers the mock hosts with a mock centralized server management platform (“mock VC”). The mock hosts are used to simulate hosts of cell sites and a mobile core of a 5G cellular network using features of the TCP. Scale tests are used to verify functionality and performance of the TCP are performed on the mock hosts without any changes to the TCP.

Abstract: A multivalent vaccine for preventing CoV infection includes more than one protein antigen derived from antigens encoded within a CoV genome. At least one of the more than one protein antigen derived from antigens encoded within a CoV genome is a protein antigen, RNA-encoded genetic information, DNA-encoded genetic information, or genetic information within a genetic vector.

Abstract: A vaccine for preventing CoV infection includes at least one DNA, RNA or protein sequence for S protein with at least one modification which is a full deletion or partial deletion of the SI region or a partial or full replacement of the SI region. A method of vaccinating a mammal subject against infection from at least one group of CoV includes separating a broad group of CoV into homology groups, creating a modified S protein containing at least one modification at its S1 region, and identifying at least one consensus sequence for each homology group which has a sequence identity of greater than 60% to all other members of the homology group. The consensus sequence is a protein sequence for the modified S protein, a DNA sequence encoding the modified S protein, and an RNA sequence encoding the modified S protein.

Abstract: Introduction of DNA fragments into eukaryotic cells exposes them to cellular enzymes, such DNases that have the ability to destroy these DNA fragments and thus reduce the function. The invention provides means and methods reducing the enzymatic destruction of linear DNA fragments transfected into cells. To this purpose, expression constructs are designed that carry genes for proteins that bind to DNA fragments and prevent the enzymatic destruction of the linear DNA fragments. The use of these genes and expression vectors in modifying packaging cells for the enhanced production of viral gene therapy vectors and methods of making these packaging cells are provided.

Abstract: The production of gene transfer vectors that have been designed as replication deficient constructs can be inefficient, thus limiting their broad use in medicine. The present invention provides a solution to this problem. It describes how the production efficiencies can be enhanced for gene transfer vectors that are produced by the transfer of DNA and RNA into production cells. The present invention lies m the use of cell cycle control in optimizing the production of gene transfer vectors. The subject of this patent is the modification of cell growth and physiology to enhance the efficiency of vector production. An example is given for the effect of certain media components on the cell cycle and production rate of a fully deleted helper virus independent adenoviral vector. Other applications of this technology are listed.

Abstract: Provided is a source-load cooperation access method for a power distribution region. The method includes: establishing a timing feature model of a distributed generator and a timing feature model of a load respectively, acquiring a timing feature of the distributed generator in an access power distribution region by using maximum likelihood estimation and acquiring a timing feature of a user which accesses the power distribution region by using classification and regression trees; and inputting the timing feature of the distributed generator and the timing feature of the user which access the power distribution region into a combination optimization model, and determining a source-load access feeder through optimization.

Abstract: The present application relates to a method for evaluating an operation of a distribution network based on data capture and Spark. The method includes: acquiring a packet from a terminal, and mirroring the packet through a mirroring port of a switch to acquire a mirror packet of the packet; analyzing the mirror packet, acquiring a 101/104 protocol packet, and storing the 101/104 protocol packet into an HDFS; acquiring the 101/104 protocol packet from the HDFS, parsing the 101/104 protocol packet on a Spark platform to acquire a parameter in the 101/104 protocol packet, and analyzing and processing the parameter to obtain a key indicator for evaluating the operation of the distribution network; and displaying the key indicator through a web page.

Abstract: Provided are a method and a device for identifying a distribution network topology error. The method includes: calculating a voltage of a coupling node to which each load belongs and obtaining a voltage sample space of coupling nodes to which all loads belong; calculating a current of a branch to which each load belongs and obtaining a current sample space of branches to which all loads belong; calculating a voltage correlation coefficient and a current correlation coefficient respectively between different loads according to the obtained voltage sample space and the current sample space; and completing verification and correction of the distribution network topology.

Abstract: Disclosed are a distribution transformer terminal and a method for monitoring a state of a distribution transformer court device. The distribution transformer terminal includes an ARM core processor, a carrier communication module connected to a court device, a sub-G wireless communication module connected to the court device and a GPS module connected to the court device. The ARM core processor is connected to the carrier communication module, the sub-G wireless communication module and the GPS module. The ARM core processor is configured to identify a phase of the court device and a court to which the court device belongs, acquire an operating state and fault information of the court device through the sub-G wireless communication module, and acquire geographical location information of the court device through the GPS module.

Abstract: The invention relates to a method for real-time scheduling of multi-energy complementary micro-grids based on a Rollout algorithm, which is technically characterized by comprising the following steps of: Step 1, setting up a moving-horizon Markov decision process model for the real-time scheduling of the multi-energy complementary micro-grids with random new-energy outputs, and establishing constraint conditions for the real-time scheduling; Step 2, establishing a target function of the real-time scheduling; Step 3, dividing a single complete scheduling cycle into a plurality of scheduling intervals, and finding one basic feasible solution meeting the constraint conditions for the real-time scheduling based on a greedy algorithm; and Step 4, finding a solution to the moving-horizon Markov decision process model for the real-time scheduling of the multi-energy complementary micro-grids by using the Rollout algorithm based on the basic feasible solution from Step 3.

Abstract: Provided are a method and a device for identifying a distribution network topology error. The method includes: calculating a voltage of a coupling node to which each load belongs and obtaining a voltage sample space of coupling nodes to which all loads belong; calculating a current of a branch to which each load belongs and obtaining a current sample space of branches to which all loads belong; calculating a voltage correlation coefficient and a current correlation coefficient respectively between different loads according to the obtained voltage sample space and the current sample space; and completing verification and correction of the distribution network topology.