Abstract: The present disclosure relates to novel pan-KRAS glutarimide-containing compounds with KRAS degradation activities, pharmaceutical compositions containing such compounds, and their use in prevention and treatment diseases and conditions.

Abstract: A method for estimating structural vibration in real time includes steps described below.

Abstract: Provided are a sound gathering device for voiceprint monitoring and a preparation method. The sound gathering device is a cone structure and includes a front end portion (1) and a rear end portion (2), the front end portion (1) is trumpet-shaped, an inner wall surface of the front end portion (1) is present a pattern array of a microstructure (3), and the microstructure (3) presenting the pattern array is formed through laser etching. A sound wave frequency monitored by the sound gathering device is 50 Hz˜10 kHz, and a sound wave enters the sound gathering device from an entrance of the front end portion (1), is reflected through the pattern array of the microstructure (3) on the inner wall surface of the front end portion (1), and is transmitted from an exit of the rear end portion (2), and a sound pressure of the exit of the rear end portion (2) is 4 times˜8 times a sound pressure of the entrance of the front end portion (1).

Abstract: A multi-target kinase inhibitor is shown in formula (I), in which R is selected from formula (a), formula (b), formula (c), formula (d), formula (e) and formula (f). The multi-target kinase inhibitor can effectively inhibit the enzymatic activities of RET, VEGFR3 and PDGFRA, and can effectively treat diseases that are regulated and controlled by multi-target kinases and are related to abnormal signal transduction pathways of the multi-target kinases, including cancers of breast, respiratory tract, brain, reproductive organ, digestive tract, urinary tract, eye, liver, skin, head and/or neck and distant metastatic cancers thereof, and lymphoma, sarcoma, leukemia and the like. The active ingredients of the pharmaceutical composition of the present invention comprise a multi-target kinase inhibitor, which accounts for 1-50 wt % of the composition.

Abstract: An imaging apparatus for an endoscope includes: a lens; an image sensor configured to capture an image via the lens; a light blocking portion provided covering the lens and the image sensor; a light source provided near the light blocking portion; and a light guide portion provided covering the light blocking portion and the light source and configured to guide light from the light source. The light blocking portion is provided so as to prevent the light from the light source from being incident on the lens and the image sensor. An end face of the lens is arranged at a position further recessed than at least an end face of the light blocking portion.

Abstract: An in-vivo camera device and an in-vivo monitoring camera system more excellent in usability are proposed. An in-vivo camera device includes a camera unit introduced into a body, a support member, and a camera-side cable. The support member has a trocar connection portion for connection with a trocar at a front end side, and is connected to the trocar in a state in which the trocar connection portion is fitted into the trocar by applying tensile force to the camera-side cable passing through the trocar. The support member is provided with a guide introduction portion that is formed to be relatively long at the front end side as a stabilization structure for stabilizing connection with the trocar.

Abstract: Portable folding solar power generation cloth bags are disclosed. One implementation comprises left and right lining plates each having holes and fixed above a lower cloth cover, left and right solar assemblies fixed above their respective lining plates, an upper cloth cover overlaying both solar assemblies and sewn to the lower cloth cover with a gap between the left and right lining plates, and junction boxes associated with respective left and right solar assemblies and embedded into the holes of the left and right lining plates, wherein a connecting line between the left and right solar assemblies may penetrate through the lower cloth cover to extend therebelow. Further, light receiving surfaces of the left and right solar assemblies are configured for external exposure from the upper cloth cover, and a foldable joint may be formed at a gap position between the upper and lower cloth covers.

Abstract: A connector unit includes a connector and a plurality of connector cap parts that are rotatably attached to a side wall of the connector. The connector cap parts each have a first space for receiving an end portion of the connector. The connector cap parts rotate toward the connector and are joined together to form a connector cap so that the first spaces communicate with each other to form a second space and that the end portion is placed in the second space.

Abstract: An in-vivo camera device and an in-vivo monitoring camera system more excellent in usability are proposed. An in-vivo camera device includes a camera unit introduced into a body, a support member, and a camera-side cable. The support member has a trocar connection portion for connection with a trocar at a front end side, and is connected to the trocar in a state in which the trocar connection portion is fitted into the trocar by applying tensile force to the camera-side cable passing through the trocar. The support member is provided with a guide introduction portion that is formed to be relatively long at the front end side as a stabilization structure for stabilizing connection with the trocar.

Abstract: A connector unit includes a connector cap and a camera-side cable connector. The connector cap includes a connection portion that movably connects the connector cap to the camera-side cable connector. The camera-side cable connector includes a first groove in which a protruding section of the connection portion is movably disposed.

Abstract: A socket electrically connectable with a pin inserted thereinto includes a pressed portion, which is pressed by the pin, and clamp pieces, which are deformed, in response to the pressed portion being pressed, into a clamp position, in which the clamp pieces clamp the pin therebetween, from an insertion position, in which the clamp pieces allow the pin to be inserted thereinto.

Abstract: A connector unit includes a connector and a plurality of connector cap parts that are rotatably attached to a side wall of the connector. The connector cap parts each have a first space for receiving an end portion of the connector. The connector cap parts rotate toward the connector and are joined together to form a connector cap so that the first spaces communicate with each other to form a second space and that the end portion is placed in the second space.

Abstract: A connector unit includes a connector cap and a camera-side cable connector. The connector cap includes a connection portion that movably connects the connector cap to the camera-side cable connector. The camera-side cable connector includes a first groove in which a protruding section of the connection portion is movably disposed.

Abstract: An in-vivo imaging device includes a camera, a support rod insertable into a tubular instrument, and a gripping portion disposed at an end portion of the support rod for gripping the camera. When the support rod is pulled up outward of a body, the gripping portion is deformed and grips the camera by coming into contact with an in-vivo side end portion of the tubular instrument.

Abstract: Disclosed is a portable folding solar power generation cloth bag, comprising: a left lining plate (3) and a right lining plate (4) fixed above a lower cloth cover (1), the left lining plate (3) and the right lining plate (4) being separately provided with a through hole (17); a left solar assembly (5) and a right solar assembly (6), wherein same are fixed above the left lining plate (3) and the right lining plate (4) respectively, a junction box (18) of the left solar assembly (5) being embedded into the through hole (17) of the left lining plate (3), a junction box (18) of the right solar assembly (6) being embedded into the through hole (17) of the right lining plate (4), and a connecting line (22) between the left solar assembly (5) and the right solar assembly (6) penetrating through the lower cloth cover (1) and reaching a position below the lower cloth cover (1); and an upper cloth cover (7) covering the upper sides of the left solar assembly (5) and the right solar assembly (6), the upper cloth cover (

Abstract: A line accurately corresponding to a natural handwriting motion is rendered on a touch panel. A pen point (11) of a stylus pen (1) is configured of a conductive rubber (12) with elasticity and a conductive fiber cloth (13) with a stretching property wound around the conductive rubber (12).

Abstract: A conductive section (13) is disposed at an inclination of 30 degrees with respect to a pen body (10). When a pen tip (12) comes into contact with or proximity to a touch surface of a touch panel (2), an angle of inclination of a length direction of the conductive section (13) with respect to the touch surface of the touch panel (2) is an angle (60 degrees to 90 degrees) at which a difference between a position of contact or proximity of the pen tip (12) on or to the touch surface and a center of gravity of a distribution of the sizes of changes in capacitance as generated by the pen tip (12) coming into contact with or proximity to the touch surface becomes constant regardless of place on the touch surface. With this, even when the pen tip is sufficiently small, variations in positions of contact or proximity to be detected when the pen body is tilted can be reduced.

Abstract: A method for controlling remote configuration includes: a configuration management terminal requesting a configuration file to be remotely configured and managed from a configuration management server; the configuration management server returning a configuration item of the configuration file to the configuration management terminal according to a configuration definition corresponding to the configuration file, with the configuration definition including the attributes of the configuration item in the corresponding configuration file; and the configuration management terminal modifying the configuration item and then submitting the modified configuration item to the configuration management server, and the configuration management terminal modifying the configuration file after modifying and verifying the submitted configuration item according to the attributes of the configuration item.

Abstract: An illuminating device includes a hood having a bottom wall and an outer peripheral wall which includes a curved reflective surface, a light device includes a light element attached to a circuit board and electrically connected to an electric cable, and a fastening device is disposed or engaged between the bottom wall of the hood and the circuit board of the light device for selectively securing the circuit board of the light device to the bottom wall of the hood. The fastening device includes one or more magnetic attractive members attached to the bottom wall of the hood, and one or more fastening members attached to the magnetic attractive members and engaged with the circuit board of the light device.

Abstract: Embodiments provide a method and an apparatus for writing and reading hard disk data. Plain-text data is encrypted by using an encryption key to obtain cipher-text data and a decryption key. The cipher-text data is written into an available area of a hard disk, and the decryption key is written into a reserved area of the hard disk.