Abstract: A visual beauty instrument includes a control module, an image acquisition module, a suction control module, a fill light module, a suction nozzle assembly and a mobile terminal. The image acquisition module collects the image signal of the suction area and feeds back the image signal to the control module. The control module analyzes the image signal and controls the suction control module and the fill light module. The suction control module sucks up the acne and blackheads on the skin surface by the suction nozzle assembly. The fill light module improves the recognition of acne and blackheads. The invention can observe the distribution and size of blackheads and acne in the inner layer of the skin and compare the number of blackheads and acne before and after suction, ensuring thorough cleaning, improving removal efficiency and preventing skin damage caused by excessive suction.

Abstract: A vacuum suction acne remover includes a main control module, a vacuum suction module including a suction head and a vacuum pump connected to the suction head and controllable by the main control module to generate a suction force at the suction head for sucking out acne from the skin, and a camera module having an imaging lens controllable by the main control module to capture the image of the area being sucked by the vacuum suction module. During the suction process of the vacuum suction module, the camera module can observe the image of the suction area, and the suction of the vacuum suction module can be adjusted according to the depth of the acne displayed on the screen to avoid blind acne removing action and incomplete cleaning and to prevent the skin from being damaged due to excessive suction, thereby improving the efficiency and cleanliness of acne removal.

Abstract: A pressure regulator includes a valve body having a fluid inlet and a fluid outlet connected by a fluid passageway. An orifice is disposed between the fluid inlet and the fluid outlet. A valve seat is disposed within the fluid passageway. A movable valve plug is disposed within the fluid passageway, and the valve plug interacts with the valve seat to selectively open or close the fluid passageway. A cage is disposed in the fluid passageway, the cage surrounds the valve plug, and the cage includes a mechanical stop that limits movement of the valve plug within the cage away from the valve seat.

Abstract: A pressure regulator includes a valve body having a fluid inlet and a fluid outlet connected by a fluid passageway. An orifice is disposed between the fluid inlet and the fluid outlet. A valve seat is disposed within the fluid passageway. A movable valve plug is disposed within the fluid passageway, and the valve plug interacts with the valve seat to selectively open or close the fluid passageway. A cage is disposed in the fluid passageway, the cage surrounds the valve plug, and the cage includes a mechanical stop that limits movement of the valve plug within the cage away from the valve seat.

Abstract: The present invention features mutant stromal cell derived factor-1 (SDF-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase IV (DPPIV), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), leukocyte elastase, cathepsin G, carboxypeptidase M, and carboxypeptidase N, but which retain chemoattractant activity.

Abstract: A pressure regulator includes a valve body having a fluid inlet and a fluid outlet connected by a fluid passageway. An orifice is disposed between the fluid inlet and the fluid outlet. A valve seat is disposed within the fluid passageway. A movable valve plug is disposed within the fluid passageway, and the valve plug interacts with the valve seat to selectively open or close the fluid passageway. A cage is disposed in the fluid passageway, the cage surrounds the valve plug, and the cage includes a mechanical stop that limits movement of the valve plug within the cage away from the valve seat.

Abstract: A multi-cone, multi-stage spray nozzle includes a nozzle body and outer and inner valve stems. The nozzle body defines an outer valve seat disposed at its distal end. The outer valve stem is slidably disposed in the nozzle body. The inner valve stem is slidably disposed in the outer valve stem. The inner valve stem occupies an open position and the outer valve stem occupies a closed position upon the application of a first pressure on the distal ends of the inner and outer valve stems. And, the inner and outer valve stems both occupy open positions upon the application of a second pressure that is greater than the first pressure on the distal ends of the inner and outer valve stems.

Abstract: The invention relates to a drug sustained-release composition, particularly a sustained-release composition comprising metoprolol and preparation method thereof. The invention also relates to a combination product comprising a sustained-release composition comprising metoprolol and a pharmaceutical composition comprising hydrochlorothiazide. The sustained-release composition comprising metoprolol according to the invention eliminates the phenomena of delayed release of such sustained-release compositions in the prior art, has a better drug release curve, and also have the advantages such as simple formula, easy operation, stable quality, strong controllability, and good reproducibility, and therefore have good application prospects.

Abstract: An assembly is provided for performing start-up testing on a fluid flow control device. The assembly includes a retainer adapted to be disposed in a valve body of the fluid flow control device, and a sealing assembly coupled to a portion of the retainer and adapted to be disposed adjacent a valve seat of the fluid flow control device. The sealing assembly includes one or more sealing elements configured to provide a seal during start-up testing at a service temperature of between approximately ?325 degrees Fahrenheit and approximately 1250 degrees Fahrenheit.

Abstract: A fluid flow control device includes a valve body defining an inlet, an outlet, and a fluid flow path extending therebetween, a valve seat ring coupled to the body that defines an orifice through which the fluid flow path passes, a cage coupled to the body that defines an interior bore, a control element slidably disposed within the interior bore of the cage, and a particle catcher at least partially disposed within an interior bore of the control element. The particle catcher includes a particle catcher body that defines an inner flow path and at least one particle catcher passage through which the fluid flow path passes. An outer surface of the particle catcher and an inner surface of the control element form a particle catching portion. The at least one particle catcher passage directs the fluid flow path downwardly into the particle catching portion.

Abstract: The present invention relates to a class of substituted heterocyclic derivative and preparation method thereof.

Abstract: A multi-cone, multi-stage spray nozzle includes a nozzle body and outer and inner valve stems. The nozzle body defines an outer valve seat disposed at its distal end. The outer valve stem is slidably disposed in the nozzle body. The inner valve stem is slidably disposed in the outer valve stem. The inner valve stem occupies an open position and the outer valve stem occupies a closed position upon the application of a first pressure on the distal ends of the inner and outer valve stems. And, the inner and outer valve stems both occupy open positions upon the application of a second pressure that is greater than the first pressure on the distal ends of the inner and outer valve stems.

Abstract: A multi-cone, multi-stage spray nozzle includes a nozzle body, a valve stem with a first valve head, and a second valve head attached to the first valve head. The first valve stem is biased into a closed position against a valve seat of the nozzle body by a bias device. The second valve head is continuously open. Upon the application of a first fluid pressure, which is less than a threshold fluid pressure, the bias device maintains the valve stem in the closed position while the second valve head is continuously open. And upon the application of a second fluid pressure, which is at least as great as the threshold fluid pressure, the valve stem moves to an open position while the second valve head remains continuously open.

Abstract: The invention provides a compound as shown by Formula I having an enzyme activity which can inhibit endocannabinoid hydrolases NAAA and/or FAAH, or a pharmaceutically acceptable salt, hydrate or solvate thereof, and a preparation method and a use of the compound.

Abstract: A valve seat apparatus for use with fluid valves is described. An example disclosed valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess at a first end of the seat ring, where the first annular recess is to receive a portion of a cage, a second annular recess proximate a second end of the seat ring opposite the first end, and where the second annular recess defines a groove in the outer surface of the seat ring, and a third annular recess adjacent the second annular recess. The example disclosed valve seat apparatus also includes a first seal assembly disposed in the third annular recess and a retainer disposed in the second annular recess to retain the seal assembly in the third annular recess.

Abstract: The invention relates to a drug sustained-release composition, particularly a sustained-release composition comprising metoprolol and preparation method thereof. The invention also relates to a combination product comprising a sustained-release composition comprising metoprolol and a pharmaceutical composition comprising hydrochlorothiazide. The sustained-release composition comprising metoprolol according to the invention eliminates the phenomena of delayed release of such sustained-release compositions in the prior art, has a better drug release curve, and also have the advantages such as simple formula, easy operation, stable quality, strong controllability, and good reproducibility, and therefore have good application prospects.

Abstract: An assembly is provided for performing start-up testing on a fluid flow control device. The assembly includes a retainer adapted to be disposed in a valve body of the fluid flow control device, and a sealing assembly coupled to a portion of the retainer and adapted to be disposed adjacent a valve seat of the fluid flow control device. The sealing assembly includes one or more sealing elements configured to provide a seal during start-up testing at a service temperature of between approximately ?325 degrees Fahrenheit and approximately 1250 degrees Fahrenheit.

Abstract: The present invention features mutant stromal cell derived factor-1 (SDF-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase IV (DPPIV), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), leukocyte elastase, cathepsin G, carboxypeptidase M, and carboxypeptidase N, but which retain chemoattractant activity.

Abstract: A valve seat apparatus for use with fluid valves is described. An example disclosed valve seat apparatus includes a seat ring having an outer surface that includes a first annular recess at a first end of the seat ring, where the first annular recess is to receive a portion of a cage, a second annular recess proximate a second end of the seat ring opposite the first end, and where the second annular recess defines a groove in the outer surface of the seat ring, and a third annular recess adjacent the second annular recess. The example disclosed valve seat apparatus also includes a first seal assembly disposed in the third annular recess and a retainer disposed in the second annular recess to retain the seal assembly in the third annular recess.

Abstract: The present invention features mutant stromal cell derived factor-1 (SDF-1) peptides that have been mutated to make them resistant to digestion by, for example, the proteases dipeptidyl peptidase IV (DPPIV), matrix metalloproteinase-2 (MMP-2), matrix metalloproteinase-9 (MMP-9), leukocyte elastase, cathepsin G, carboxypeptidase M, and carboxypeptidase N, but which retain chemoattractant activity.