Patents by Inventor Yan Su
Yan Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12637442Abstract: The present disclosure provides an organic electronic material containing a nitrogen heterocycle and a preparation method and use thereof, and relates to the technical field of organic electroluminescence. Nitrogen-containing heterocycles such as pyridine, triazine or pyrimidine are introduced into a main structure of phenanthrene, such that the electronegativity of the material is enhanced, and the electron transport performance and the thermal stability of a compound are improved. The organic electron transport material provided by the present disclosure has a relatively good thermal stability, a high luminous efficiency and a high luminous purity. An organic light-emitting device prepared from the organic electronic material has effects of reducing a driving voltage, improving a luminous efficiency, enabling color purity to be excellent and prolonging a service life.Type: GrantFiled: December 1, 2020Date of Patent: May 26, 2026Assignee: SHANGHAI CHUANQIN NEW MATERIAL CO., LTDInventors: Yan Su, Haitao Zhou, Zhuju Huang
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Patent number: 12474346Abstract: The present disclosure relates to methods and kits for analyzing a macromolecule analyte in a cyclic manner that incorporate basic steps of the ProteoCode™ protein sequencing assay and in addition incorporate approaches that allow to control template independent nucleotide addition by the DNA polymerase, and thus ensure successful multi-cycling encoding. Three different approaches are proposed herein to prevent heterogeneity in the spacer length of the extended recording tag created during the primer extension reaction. The disclosed methods allow for highly-parallelized, accurate and sensitive macromolecule characterization.Type: GrantFiled: October 10, 2022Date of Patent: November 18, 2025Inventors: Norihito Muranaka, Yan Su, Kevin L. Gunderson
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Publication number: 20250266708Abstract: A multi-machine parallel energy storage system and a charging and discharging control method thereof are provided. The multi-machine parallel energy storage system includes: a single renewable energy device, at least two energy storage devices, an AC bus and a load. When the renewable energy device is connected to any energy storage device, that device becomes the master while others serve as slaves, and the master device is configured to: dynamically acquire first data, second data and third data; determine the current state of the multi-machine parallel energy storage system according to the first data, the second data and the third data; control the renewable energy device to provide electric energy to the master device when the current state meets the charging condition; and control the renewable energy device to provide electric energy to the slave device when the master device reaches a fully charged state.Type: ApplicationFiled: April 30, 2025Publication date: August 21, 2025Applicant: SHENZHEN POWEROAK NEWENER CO.,LTDInventors: Hui Ma, Zhihua Guo, Wentao Cang, Xiaoqun Meng, Yan Su
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Patent number: 12385916Abstract: A set of serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis are provided. The set of the serum metabolic biomarkers includes 17 serum metabolic biomarkers. The 17 serum metabolic biomarkers are verified to be associated with tuberculosis based on the level changes of these biomarkers. The 17 metabolites includes taurine, homocysteine, uric acid, ascorbic acid, suberylglycine, uridine, dopamine 4-sulfate, inosinic acid, glyceraldehyde phosphate, [3-methoxy-4-(phosphoryl)phenyl]carbonyl sulfonic acid, nuclomedone, n4-cyclopropyl-6-(2,3-dichlorophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-diimine, 1-[2-chlorine-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole, tetrachloro-phthalic anhydride, malotilate, fulvic acid, and L-neopterin. The serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis can assist doctors in accurately diagnosing the disease, which is of great significance for the diagnosis and mass screening for drug-resistant tuberculosis.Type: GrantFiled: July 12, 2023Date of Patent: August 12, 2025Assignee: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong Huang, Yajing Liu, Yan Su, Chao Zhang
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Publication number: 20250237660Abstract: The present disclosure relates to methods and kits for analyzing a macromolecule analyte in a cyclic manner that incorporate basic steps of the ProteoCode™ protein sequencing assay and in addition incorporate approaches that allow to control template independent nucleotide addition by the DNA polymerase, and thus ensure successful multi-cycling encoding. Three different approaches are proposed herein to prevent heterogeneity in the spacer length of the extended recording tag created during the primer extension reaction. The disclosed methods allow for highly-parallelized, accurate and sensitive macromolecule characterization.Type: ApplicationFiled: October 10, 2022Publication date: July 24, 2025Applicant: ENCODIA, INC.Inventors: Norihito MURANAKA, Yan SU, Kevin L. GUNDERSON
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Patent number: 12339282Abstract: The present application provides a novel coronavirus antibody detection kit based on magnetic particle chemiluminescence. The detection kit includes: streptavidin magnetic particles, biotin-labeled novel coronavirus antigens, an acridine sulfonamide-labeled secondary antibody, a sample diluent and a quality control material; wherein the biotin-labeled novel coronavirus antigens include a recombinant nucleocapsid protein and a recombinant spike protein S1. The sample to be tested, the biotin-labeled antigens and the streptavidin magnetic particles are mixed, incubated and washed, and then the acridine sulfonamide-labeled antibody is added to form a magnetic particle-streptavidin-biotin-antigen-novel coronavirus antibody-secondary antibody complex, and then the luminous intensity is detected to qualitatively determine the sample to be tested.Type: GrantFiled: March 24, 2021Date of Patent: June 24, 2025Assignee: Dynamiker Biotechnology (Tianjin) Co., Ltd.Inventors: Chunlong Liu, Zhou Zhang, Shaohua Ma, Jiashun Wang, Yan Su, Zeqi Zhou
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Patent number: 12313636Abstract: A set of serum metabolic biomarkers and detection kit for detecting tuberculosis are provided. The set of the serum metabolic biomarkers includes 17 serum metabolic biomarkers. The 17 serum metabolic biomarkers comprising D-Leucic acid, Leucinic acid, L-Cystine, MG(0:0/14:0/0:0), S-Lactoylglutathione, Octacosanoic acid, Cer(d18:1/12:0), Raffinose, LysoPC(20:1(11Z)/0:0), LysoPC(22:4(7Z,10Z,13Z,16Z)/0:0), PC(18:1(9Z)e/2:0), Torvoside G(TG(15:0/15:0/15:0)), CE(16:1(9Z)), all-trans-Heptaprenyl diphosphate, PC(15:0/16:0), NADP, TG(20:0/20:0/20:1(11Z)). The 17 serum metabolic biomarkers are verified to be associated with tuberculosis based on the level changes of these biomarkers. The tuberculosis detection model based on the levels of the 17 metabolic biomarkers can achieve an area under the ROC curve of 99.5%, sensitivity of 98.2%, and specificity of 95.8% in detecting tuberculosis.Type: GrantFiled: July 12, 2023Date of Patent: May 27, 2025Assignee: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong Huang, Yajing Liu, Yan Su, Chao Zhang
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Patent number: 12298317Abstract: A tuberculosis detection kit includes diagnostic reagents for 17 serum metabolites of patients with tuberculosis, the detecting reagent being used for quantitative detection of the 17 serum metabolites of the patients with tuberculosis, the 17 serum metabolites comprising D-Leucic acid, Leucinic acid, L-Cystine, MG(0:0/14:0/0:0), S-Lactoylglutathione, Octacosanoic acid, Cer(d18:1/12:0), Raffinose, LysoPC(20:1(11Z)/0:0), LysoPC(22:4(7Z,10Z,13Z,16Z)/0:0), PC(18:1(9Z)e/2:0), Torvoside G(TG(15:0/15:0/15:0)), CE(16:1(9Z)), all-trans-Heptaprenyl diphosphate, PC(15:0/16:0), NADP, TG(20:0/20:0/20:1(11Z)).Type: GrantFiled: May 11, 2024Date of Patent: May 13, 2025Assignee: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong Huang, Yajing Liu, Yan Su, Chao Zhang
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Patent number: 12265239Abstract: Provided is a wide angle application high reflective mirror having a reflection band partially overlapping in a wavelength range of 800-4000 nm. The mirror comprises a film system in which a plurality of high refractive index film layers and a plurality of low refractive index film layers that are alternately stacked, and the material of the high refractive index film layer is one of SiH, SiOxHy, or SiOxNy, or a mixture thereof. The highly reflective mirror can achieve a reflectance greater than 99% with an incident angle ranging from 0 to 60 degrees over a large angle range.Type: GrantFiled: September 12, 2018Date of Patent: April 1, 2025Assignee: II-VI DELAWARE, INC.Inventors: Li Wu, Zhe Liu, Guanglong Yu, Yu Li, Yan Su, Zhiqiang Lin
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Patent number: 12196753Abstract: A kit for detecting drug-resistant tuberculosis, includes: detection reagents, configured to perform quantitative detection on 17 serum metabolites of patients with tuberculosis, the 17 serum metabolites comprising: taurine, homocysteine, uric acid, ascorbic acid, suberylglycine, uridine, dopamine 4-sulfate, inosinic acid, glyceraldehyde phosphate, [3-methoxy-4-(phosphoryl)phenyl]carbonyl sulfonic acid, nuclomedone, n4-cyclopropyl-6-(2,3-dichlorophenyl)-1,2,3,4-tetrahydropyrimidine-tetrachlorophthalic anhydride, malotilate, fulvic acid, and L-neopterin.Type: GrantFiled: May 11, 2024Date of Patent: January 14, 2025Assignee: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong Huang, Yajing Liu, Yan Su, Chao Zhang
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Publication number: 20240295569Abstract: A tuberculosis detection kit includes diagnostic reagents for 17 serum metabolites of patients with tuberculosis, the detecting reagent being used for quantitative detection of the 17 serum metabolites of the patients with tuberculosis, the 17 serum metabolites comprising D-Leucic acid, Leucinic acid, L-Cystine, MG(0:0/14:0/0:0), S-Lactoylglutathione, Octacosanoic acid, Cer(d18:1/12:0), Raffinose, LysoPC(20:1(11Z)/0:0), LysoPC(22:4(7Z,10Z,13Z,16Z)/0:0), PC(18:1(9Z)e/2:0), Torvoside G(TG(15:0/15:0/15:0)), CE(16:1(9Z)), all-trans-Heptaprenyl diphosphate, PC(15:0/16:0), NADP, TG(20:0/20:0/20:1(11Z)).Type: ApplicationFiled: May 11, 2024Publication date: September 5, 2024Applicant: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong HUANG, Yajing LIU, Yan SU, Chao ZHANG
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Publication number: 20240295555Abstract: A kit for detecting drug-resistant tuberculosis, includes: detection reagents, configured to perform quantitative detection on 17 serum metabolites of patients with tuberculosis, the 17 serum metabolites comprising: taurine, homocysteine, uric acid, ascorbic acid, suberylglycine, uridine, dopamine 4-sulfate, inosinic acid, glyceraldehyde phosphate, [3-methoxy-4-(phosphoryl)phenyl]carbonyl sulfonic acid, nuclomedone, n4-cyclopropyl-6-(2,3-dichlorophenyl)-1,2,3,4-tetrahydropyrimidine-tetrachlorophthalic anhydride, malotilate, fulvic acid, and L-neopterin.Type: ApplicationFiled: May 11, 2024Publication date: September 5, 2024Applicant: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong HUANG, Yajing LIU, Yan SU, Chao ZHANG
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Publication number: 20240294981Abstract: The present disclosure relates to macromolecule analysis methods which employ nucleic acid encoding of molecular recognition events in a cyclical manner. Also provided herein are methods and related kits for transferring information using a plurality of enzymes, including for performing joining and cleavage reactions in a cyclical manner with nucleic acid molecules associated with the macromolecule for analysis. In some embodiments, the macromolecule for analysis comprises a polypeptide, and the disclosed methods and related kits are for high-throughput polypeptide analysis, including polypeptide sequencing.Type: ApplicationFiled: February 23, 2024Publication date: September 5, 2024Inventors: Mark S. CHEE, Yan SU
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Publication number: 20240132979Abstract: A set of primers and probes for simultaneous detection of Cymbidium mosaic virus (CymMV), Odontoglossum ringspot virus (ORSV), and Cymbidium ringspot virus (CymRSV) and a method for detecting CymMV, ORSV, and CymRSV, along with a method for their detection, are disclosed. The method involves designing multiplex real-time quantitative PCR detection primers and probes for CymMV, ORSV, and CymRSV and applying these primers and probes to the real-time quantitative PCR simultaneous detection of CymMV, ORSV, and CymRSV. It allows for faster detection of CymMV, ORSV, and CymRSV, taking only one-third of the time compared to uniplex real-time quantitative PCR technology, thereby reducing testing costs by approximately ? to ½ for each sample. The primers and probes are highly specific and sensitive, with a sensitivity as low as 1 to 10 copies. It provides an efficient and feasible detection method for early detection and prevention of CymMV, ORSV, and CymRSV.Type: ApplicationFiled: January 1, 2024Publication date: April 25, 2024Applicants: FLOWER RESEARCH INSTITUTE OF YUNNAN ACADEMY OF AGRICULTURAL SCIENCES, YUNNAN UNIVERSITYInventors: Lihua Wang, Aiqing Sun, Xuewei Wu, Suping Qu, Yiping Zhang, Xiumei Yang, Yan Su, Feng Xu, Lifang Zhang
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Publication number: 20230363335Abstract: The present disclosure provides a standardized and virus-free rapid propagation method of Dianthus caryophyllus, belonging to the technical field of asexual propagation. The method includes the following steps: conducting virus detection on a Dianthus caryophyllus explant, and inoculating the explant into an induction medium for induction culture; after the explant germinates, cutting buds, and determining whether a virus-free treatment is required according to a virus detection result, and continuing cultivating the buds; after cultivating to obtain cluster buds, inoculating the cluster buds into an expanding propagation medium for expanding propagation, and conducting the virus detection to eliminate a virus-carrying material; conducting expanding propagation on a virus-free material to a certain base, and transferring the virus-free material to a rooting medium for rooting culture.Type: ApplicationFiled: June 21, 2022Publication date: November 16, 2023Applicant: Flower Research Institute, Yunnan Academy of Agricultural SciencesInventors: Yiping ZHANG, Yunhui QU, Yan SU, Yalian JIANG, Feng XU, Jihua WANG, Suping QU, Lihua WANG, Lifang ZHANG, Xiumei YANG, Axiang ZHAO
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Publication number: 20230358766Abstract: A set of serum metabolic biomarkers and detection kit for detecting tuberculosis are provided. The set of the serum metabolic biomarkers includes 17 serum metabolic biomarkers. The 17 serum metabolic biomarkers comprising D-Leucic acid, Leucinic acid, L-Cystine, MG(0:0/14:0/0:0), S-Lactoylglutathione, Octacosanoic acid, Cer(d18:1/12:0), Raffinose, LysoPC(20:1(11Z)/0:0), LysoPC(22:4(7Z,10Z,13Z,16Z)/0:0), PC(18:1(9Z)e/2:0), Torvoside G(TG(15:0/15:0/15:0)), CE(16:1(9Z)), all-trans-Heptaprenyl diphosphate, PC(15:0/16:0), NADP, TG(20:0/20:0/20:1(11Z)). The 17 serum metabolic biomarkers are verified to be associated with tuberculosis based on the level changes of these biomarkers. The tuberculosis detection model based on the levels of the 17 metabolic biomarkers can achieve an area under the ROC curve of 99.5%, sensitivity of 98.2%, and specificity of 95.8% in detecting tuberculosis.Type: ApplicationFiled: July 12, 2023Publication date: November 9, 2023Applicant: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong HUANG, Yajing LIU, Yan SU, Chao ZHANG
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Publication number: 20230349900Abstract: A set of serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis are provided. The set of the serum metabolic biomarkers includes 17 serum metabolic biomarkers. The 17 serum metabolic biomarkers are verified to be associated with tuberculosis based on the level changes of these biomarkers. The 17 metabolites includes taurine, homocysteine, uric acid, ascorbic acid, suberylglycine, uridine, dopamine 4-sulfate, inosinic acid, glyceraldehyde phosphate, [3-methoxy-4-(phosphoryl)phenyl]carbonyl sulfonic acid, nuclomedone, n4-cyclopropyl-6-(2,3-dichlorophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-diimine, 1-[2-chlorine-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole, tetrachloro-phthalic anhydride, malotilate, fulvic acid, and L-neopterin. The serum metabolic biomarkers and detection kit for detecting drug-resistant tuberculosis can assist doctors in accurately diagnosing the disease, which is of great significance for the diagnosis and mass screening for drug-resistant tuberculosis.Type: ApplicationFiled: July 12, 2023Publication date: November 2, 2023Applicant: Zhejiang SUKEAN Pharmaceutical Co., Ltd.Inventors: Pintong HUANG, Yajing LIU, Yan SU, Chao ZHANG
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Publication number: 20230296601Abstract: The present application provides a novel coronavirus antibody detection kit based on magnetic particle chemiluminescence. The detection kit includes: streptavidin magnetic particles, biotin-labeled novel coronavirus antigens, an acridine sulfonamide-labeled secondary antibody, a sample diluent and a quality control material; wherein the biotin-labeled novel coronavirus antigens include a recombinant nucleocapsid protein and a recombinant spike protein S1. The sample to be tested, the biotin-labeled antigens and the streptavidin magnetic particles are mixed, incubated and washed, and then the acridine sulfonamide-labeled antibody is added to form a magnetic particle-streptavidin-biotin-antigen-novel coronavirus antibody-secondary antibody complex, and then the luminous intensity is detected to qualitatively determine the sample to be tested.Type: ApplicationFiled: March 24, 2021Publication date: September 21, 2023Inventors: Chunlong Liu, Zhou Zhang, Shaohua Ma, Jiashun Wang, Yan Su, Zeqi Zhou
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Publication number: 20230086539Abstract: The present disclosure provides an organic electronic material containing a nitrogen heterocycle and a preparation method and use thereof, and relates to the technical field of organic electroluminescence. Nitrogen-containing heterocycles such as pyridine, triazine or pyrimidine are introduced into a main structure of phenanthrene, such that the electronegativity of the material is enhanced, and the electron transport performance and the thermal stability of a compound are improved. The organic electron transport material provided by the present disclosure has a relatively good thermal stability, a high luminous efficiency and a high luminous purity. An organic light-emitting device prepared from the organic electronic material has effects of reducing a driving voltage, improving a luminous efficiency, enabling color purity to be excellent and prolonging a service life.Type: ApplicationFiled: December 1, 2020Publication date: March 23, 2023Applicant: SHANGHAI CHUANQIN NEW MATERIAL CO., LTDInventors: Yan SU, Haitao ZHOU, Zhuju HUANG
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Publication number: 20210356633Abstract: Provided is a wide angle application high reflective mirror having a reflection band partially overlapping in a wavelength range of 800-4000 nm. The mirror comprises a film system in which a plurality of high refractive index film layers and a plurality of low refractive index film layers that are alternately stacked, and the material of the high refractive index film layer is one of SiH, SiOxHy, or SiOxNy, or a mixture thereof. The highly reflective mirror can achieve a reflectance greater than 99% with an incident angle ranging from 0 to 60 degrees over a large angle range.Type: ApplicationFiled: December 9, 2018Publication date: November 18, 2021Inventors: Li WU, Zhe LIU, Guanglong YU, Yu LI, Yan SU, Zhiqiang LIN