Abstract: An aqueous dispersion and an aqueous coating composition comprising the aqueous dispersion, and the aqueous coating composition providing coatings made therefrom with improved anti-corrosion property and good water resistance and block resistance.

Abstract: An aqueous dispersion comprising a silicone-acrylic polymer with reduced coagulum, a process of preparing the aqueous dispersion, and an aqueous coating composition comprising the aqueous dispersion and providing coatings with improved corrosion resistance.

Abstract: In combination with conventional therapies (e.g., targeted therapy, chemotherapy, and angiogenesis inhibitors etc.), immunotherapies targeting checkpoint molecules have shown promise in the treatment of solid or liquid tumors. However, apoptotic regulatory T cells (Treg) induced by such therapies often become more suppressive in the tumor microenvironment (TME), through increased generation of adenosine tightly controlled by ectonucleotidases, viz. CD39 and CD73. CD39/ENTPD1, a novel checkpoint molecule, is highly expressed and activated on the tumor vasculature and infiltrating immune cells, promoting tumor growth. Deletion or blockade of CD39 enhances anti-tumor activity by augmenting anti-tumor immune responses and inhibiting tumor angiogenesis.

Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.

Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.

Abstract: The present disclosure provides a wire structure for a display panel, a display panel, a display device, and a manufacturing method. The wire structure includes a first wire layer and a thermally conductive layer above the first wire layer. A thermal conductivity of the thermally conductive layer is greater than a thermal conductivity of the first wire layer.

Abstract: An organic light emitting diode array substrate and an electronic device. The organic light emitting diode array substrate includes a display region, and a first package test electrode and a first package test lead which are outside the display region. The display region includes a first power supply line and a first signal line; the first package test lead is configured to connect the first package test electrode with the first power supply line to provide a first supply voltage for the display region; the first signal line is configured to provide a first electrical signal for the display region; and a thermal conductivity of the first package test lead is higher than a thermal conductivity of the first signal line.

Abstract: The invention provides anti-Jagged1 antibodies and methods of using the same.

Abstract: The invention provides antagonistic antibodies to BACE1 and methods of using the same for the treatment of neurological disease and disorders

Abstract: A spin torque reversal assisted magnetic recording (STRAMR) structure is disclosed wherein a spin torque oscillator (STO) is formed in the write gap (WG) and generates one or both of a radio frequency (RF) field on a magnetic bit to lower the required write field during a write process, and a spin torque on a field generation layer (FGL) in the STO that flips a FGL magnetization to a direction opposing the WG field thereby increasing reluctance in the WG and causing larger write field output from the main pole (MP). The FGL is between two spin preserving layers that each conduct spin polarized current from an adjoining spin polarization (SP) layer. Current is applied from the MP and trailing shield to the SP layers, and returns to a direct current source through a lead from the FGL. STO sidewalls are self-aligned to a MP tip upper portion.

Abstract: A spin transfer torque reversal assisted magnetic recording (STRAMR) device is disclosed wherein a flux change layer (FCL) is formed between a main pole (MP) trailing side and a trailing shield (TS). The FCL has a magnetization that flips to a direction substantially opposing the write gap magnetic field when a direct current (DC) of sufficient current density is applied across the STRAMR device thereby increasing reluctance in the WG and producing a larger write field output at the air bearing surface. Heat transfer in the STRAMR device is enhanced and production cost is reduced by enlarging the STRAMR width to be essentially equal to that of the TS, and where the TS and STRAMR widths are formed using the same process steps. Bias voltage is used to control the extent of FCL flipping to a center portion to optimize the gain in area density capability in the recording system.

Abstract: Provided herein are anti-Ly6G6D (lymphocyte antigen 6 complex, locus G61) antibodies and methods of using the same.

Abstract: The present disclosure discloses an organic light emitting display device. The organic light emitting display device includes a substrate, an initializing voltage input line, a first electrode line, a thin film transistor, and an organic light emitting diode arranged on the substrate. The thin film transistor includes a first electrode, a second electrode and a control electrode, and the first electrode is coupled to the first electrode line, the initializing voltage input line is provided in the same layer and is made of the same material as one of the first electrode, the second electrode and the control electrode of the thin film transistor, and an extension direction of the initializing voltage input line is substantially the same as an extension direction of the first electrode line.

Abstract: A bottom shield in a read head is modified by including a non-magnetic decoupling layer and second magnetic layer on a conventional first magnetic layer. The second magnetic layer has a magnetization that is not exchange coupled to the first magnetic layer, and a domain structure that is not directly affected by stray fields due to domain wall motion in the first magnetic layer. Accordingly, the modified bottom shield reduces shield related noise on the reader and will provide improved signal to noise (SNR) ratio and better reader stability. The second magnetic layer may be further stabilized with one or both of an antiferromagnetic coupling scheme, and insertion of an antiferromagnetic pinning layer. In dual readers, the modified bottom shield is used in either the bottom or top reader although in the latter, first magnetic layer thickness is reduced to maintain reader-to-reader spacing and acceptable bit error rate (BER).

Abstract: A Spin Hall Effect (SHE) assisted magnetic recording device is disclosed wherein a SHE layer comprising a giant Spin Hall Angle material is formed in a write gap between a main pole (MP) trailing side and trailing shield (TS). The SHE layer contacts either the MP or TS, and has a front side at the air bearing surface or recessed therefrom. In one embodiment, a current (I1) is applied between the MP trailing side and SHE layer and is spin polarized to generate a first spin transfer torque that tilts a local MP magnetization to a direction that enhances a MP write field. In a second embodiment, a current (I2) is applied between the SHE layer and TS and is spin polarized to generate a second spin transfer torque that tilts a local TS magnetization to a direction that increases the TS return field and improves bit error rate.

Abstract: A spin transfer torque reversal assisted magnetic recording (STRAMR) structure is disclosed wherein two flux change layers (FCL1 and FCL2) are formed within a write gap (WG) and between a main pole (MP) trailing side and trailing shield (TS). Each FCL has a magnetization that flips to a direction substantially opposing a WG field when a direct current of sufficient current density is applied across the STRAMR device thereby increasing reluctance in the WG and producing a larger write field output at the air bearing surface. A reference layer (RL1) is used to reflect spin polarized electrons that exert spin torque on FCL1 and cause FCL1 magnetization to flip. A second reference layer (or the MP or TS) is employed to reflect spin polarize electrons that generate spin torque on FCL2 and flip FCL2 magnetization. Non-spin polarization preserving layers and spin polarization preserving layers are also in the STRAMR structure.

Abstract: The present invention relates to bispecific antibodies that bind to transferrin receptor and BACE1 and methods of using the same.

Abstract: Provided herein are systems and methods of regulating vehicle powertrains in electric vehicles using driving patterns. A vehicle control unit (VCU) can be disposed in the electric vehicle. The VCU can maintain operation profiles. Each operation profile can specify a set of regulation parameters to be applied to the vehicle powertrain for motion measurement and an engine measurement identified as associated with an environmental condition. The VCU can compare the motion measurement and the engine measurement acquired from the sensor with the motion measurement and the engine measurement specified by an operation profile. The VCU can select an operation profile based on the comparison. The VCU can identify the set of regulation parameters for an environmental condition specified by the operation profile. The VCU can apply the set of regulation parameters to the vehicle powertrain to control the propulsion of the electric vehicle in accordance with the operation profile.

Abstract: Provided herein are systems and methods for allocating power distribution in hybrid vehicle drivetrains. An engine instrumentation unit can acquire engine measurements on a hybrid drivetrain of a vehicle. The engine measurements can include a fuel use measurement of a combustion engine and a battery use measurement of an electric motor. A vehicle control unit can maintain a power distribution profile. Each power distribution profile can define a power allocation to the combustion engine and a power allocation to the electric motor specified for engine measurements as associated with an environmental condition. The vehicle control unit can compare the engine measurements. The vehicle control unit can select a power distribution profile based on the comparison. The vehicle control unit can set a power splitter to transfer of the mechanical power from the combustion engine and the electric motor to a differential unit in accordance with the power distribution profile.

Abstract: A robot arm including a first joint, a second joint, and a coupling element is provided. The first joint has a first inclined surface. The second joint is jointed to the first joint and has a second inclined surface. The coupling element has a third inclined surface and a fourth inclined surface opposite to the third inclined surface, wherein the third inclined surface contacts the first inclined surface, and the fourth inclined surface contacts the second inclined surface.