Abstract: The present invention belongs to the field of medicinal chemistry. Disclosed are a pyridine oxynitride, a preparation method therefor and the use thereof. Specifically, the present invention relates to a series of sodium ion channel blockers with a new structure, a preparation method therefor and the use thereof. The structure thereof is as shown in general formula (I) below. The compounds or a stereoisomer, a racemate, a geometric isomer, a tautomer, a prodrug, a hydrate, a solvate, or a pharmaceutically acceptable salt thereof and a pharmaceutical composition can be used for treating or/and preventing related diseases mediated by a sodium ion channel (NaV).

Abstract: Systems, methods, and instrumentalities for sub-block motion derivation and motion vector refinement for merge mode may be disclosed herein. Video data may be coded (e.g., encoded and/or decoded). A collocated picture for a current slice of the video data may be identified. The current slice may include one or more coding units (CUs). One or more neighboring CUs may be identified for a current CU. A neighboring CU (e.g., each neighboring CU) may correspond to a reference picture. A (e.g., one) neighboring CU may be selected to be a candidate neighboring CU based on the reference pictures and the collocated picture. A motion vector (MV) (e.g., collocated MV) may be identified from the collocated picture based on an MV (e.g., a reference MV) of the candidate neighboring CU. The current CU may be coded (e.g., encoded and/or decoded) using the collocated MV.

Abstract: Sketch copy mode may be used to code blocks comprising irregular lines, syntax redundancy may be removed from blocks with special characteristics, and/or run value coding may be simplified. The parsing dependencies in palette coding design may be removed. For example, the context modeling dependency of the syntax element palette_transpose_flag may be removed, for example, by simplifying the corresponding context model. The context modeling of the syntax element palette_mode may be removed, for example, by using run-length coding without using context. The syntax parsing dependencies and/or the syntax signaling dependencies that are related with escape color signaling may be removed. A palette table generation process may handle input screen content video with high bit depths, for example, at the encoder side.

Abstract: The present disclosure provides systems and methods for signaling and using a palette mode in video processing. According to certain disclosed embodiments, an exemplary video processing method includes: receiving a first palette entry for palette coding a target coding unit (CU); determining whether the target CU is part of a single-tree slice; determining whether the target CU is coded with separate luma and chroma trees; and in response to the target CU being determined to be part of a single-tree slice and be coded with separate luma and chroma trees, decoding a first component of the target CU based on the first palette entry, and decoding a second component of the target CU based on a default palette entry.

Abstract: Systems, methods, and instrumentalities may be provided for determining whether to bypass bi-directional optical flow (BDOF) if BDOF is used in combination with bi-prediction with coding unit (CU) weights (e.g., generalized bi-prediction (GBi)). A coding system may combine coding modes, coding techniques, and/or coding tools. The coding system may include a wireless transmit/receive unit (WTRU). For example, the coding system may combine BDOF and bi-prediction with GU weights (BCW). BDOF may include refining a motion vector associated with a current CU based at least in part on gradients associated with a location in the current CU. The coding system may determine that BDOF is enabled, and/or that bi-prediction with CU weights is enabled for the current CU. The coding system's determination that bi-prediction with CU weights is enabled and/or that BDOF is enabled may be based on one or more indications.

Abstract: A method for video processing using Cross-Component Adaptive Loop Filter (CCALF) is provided. The method includes filtering decoded video content using a CCALF, wherein the CCALF is a 24-tap 9×9 filter.

Abstract: Embodiments of video coding systems and methods are described for reducing coding latency introduced by decoder-side motion vector refinement (DMVR). In one example, two non-refined motion vectors are identified for coding of a first block of samples (e.g. a first coding unit) using bi-prediction. One or both of the non-refined motion vectors are used to predict motion information for a second block of samples (e.g. a second coding unit). The two non-refined motion vectors are refined using DMVR, and the refined motion vectors are used to generate a prediction signal of the first block of samples. Such embodiments allow the second block of samples to be coded substantially in parallel with the first block without waiting for completion of DMVR on the first block. In additional embodiments, optical-flow-based techniques are described for motion vector refinement.

Abstract: The present disclosure provides a computer-implemented method for encoding video. The method includes: generating training data based on one or more video sequences, the training data including a structure similarity index comprising at least one of structure similarity index (SSIM) or multi-scale-structural similarity index (MS-SSIM); training a rate-distortion optimization (RDO) model using the training data; processing the one or more video sequences using the rate-distortion optimization model.

Abstract: A method for performing combined inter and intra prediction (CIIP) includes determining the CIIP being enabled for a target block; determining a first intra prediction mode of the target block using a template-based intra mode derivation (TIMD) method; generating an intra predictor of the target block with the first intra prediction mode; and obtaining a final predictor of the target block by weighted averaging the intra predictor of the target block and an inter predictor of the target block.

Abstract: Systems, methods, and instrumentalities are disclosed relating to intra prediction of a video signal based on mode-dependent subsampling. A block of coefficients associated with a first sub block of a video block, one or more blocks of coefficients associated with one or more remaining sub blocks of the video block, and an indication of a prediction mode for the video block may be received. One or more interpolating techniques, a predicted first sub block, and the predicted sub blocks of the one or more remaining sub blocks may be determined. A reconstructed first sub block and one or more reconstructed remaining sub blocks may be generated. A reconstructed video block may be formed based on the prediction mode, the reconstructed first sub block, and the one or more reconstructed remaining sub blocks.

Abstract: A frequency modulation circuit can include: a modulation circuit configured to generate a digital modulation signal and an analog modulation signal according to an input signal of the frequency modulation circuit; and a phase-locked loop having a voltage-controlled oscillator configured to receive a reference frequency, and to modulate a frequency of an output signal of the voltage-controlled oscillator according to the analog modulation signal and the digital modulation signal.

Abstract: The present disclosure provides a computer-implemented method for video processing. The method includes deriving a total number by summing a number of reference picture list structures in sequence parameter set (SPS) and one; allocating memory for the total number of reference picture list structures in response to a reference picture list structure being signaled in a picture header of a current picture or a slice header of a current slice; and processing a current picture or a current slice using the allocated memory.

Abstract: A streaming device may request and download multi-layer video segments based on a number of factors including the artistic interest associated with the video segments and/or the status of a buffer area managed by the streaming device. The multi-layer segments may be coded using scalable coding techniques or a combination of scalable coding and simulcast coding techniques by which each of the video segments may be coded into one or more representations of different qualities and/or bitrates. When requesting the multi-layer segments, the streaming device may ensure that the fullness of the buffer area falls between a buffer underflow threshold and a backfilling threshold under various network conditions. The streaming device may estimate the available network bandwidth in order to facilitate the scheduling decisions. The streaming device may consider the artistic interest associated with the video segments during scheduling and may give priority to those segments with higher artistic interest.

Abstract: Video encoding and decoding techniques for bi-prediction with weighted averaging are disclosed. According to certain embodiments, a computer-implemented video signaling method includes signaling, by a processor to a video decoder, a bitstream including weight information used for prediction of a coding unit (CU). The weight information indicates: if weighted prediction is enabled for a bi-prediction mode of the CU, disabling weighted averaging for the bi-prediction mode.

Abstract: Embodiments contemplate coding video data by generating a video encoded bitstream that may include reference picture set (RPS) extensions for inter-layer reference pictures, and the extensions may include inter-layer delta Picture Order Counts (POCs). Embodiments may also include signaling that lower layer reference pictures may be available in a lower layer decoder picture buffer (DPB), and/or an aggregate DPB, that may be added to the RPS set of a higher layer. The bitstream may include a signal indicating whether the higher layer RPS may be specified by a lower layer RPS, and the lower layer RPS may be temporal, inter-layer prediction (ILP), or both.

Abstract: The present disclosure provides systems and methods for constructing a merge candidate list used for video processing. One exemplary method includes: inserting a set of spatial merge candidates to a merge candidate list of a coding block, wherein the set of spatial merge candidates are inserted according to an order of: top neighboring block, left neighboring block, top neighboring block, left neighboring block and above-left neighboring block. The method can further include adding to the merge candidate list at least one of: a temporal merge candidate from collocated coding units, a history-based motion vector predictor (HMVP) from a First-In, First-Out (FIFO) table, a pairwise average candidate, or a zero motion vector.

Abstract: Methods and apparatuses for video processing include: filtering a luma sample using a first filter in a video coding process, the first filter being represented as a cross shape; filtering a chroma sample associated with the luma sample using a second filter in the video coding process; determining, based on the filtered luma sample, a residual correction value corresponding to the chroma sample; and determining a corrected chroma sample based on the residual correction value and the filtered chroma sample.

Abstract: A compound represented by formula (I), an optical isomer thereof and a pharmaceutically acceptable salt thereof, as well as an application of said compound as an FXIa inhibitor.

Abstract: Systems, methods, and instrumentalities are disclosed for discontinuous face boundary filtering for 360-degree video coding. A face discontinuity may be filtered (e.g., to reduce seam artifacts) in whole or in part, for example, using coded samples or padded samples on either side of the face discontinuity. Filtering may be applied, for example, as an in-loop filter or a post-processing step. 2D positional information related to two sides of the face discontinuity may be signaled in a video bitstream so that filtering may be applied independent of projection formats and/or frame packing techniques.

Abstract: Methods and systems for performing in-loop luma mapping with chroma scaling are described. One of the methods includes receiving a chrome block and a luma block associated with a picture. The method also includes determining luma scaling information associated with the luma block. The method also includes determining a luma scaling factor of the luma block based on the luma scaling information. The method also includes determining the chroma scaling factor based on a value of the luma scaling factor. The method also includes processing residuals of the chroma block using the chroma scaling factor.