Abstract: A photodiode chip, a photodiode, and a method for controlling a wavelength of a photodiode are provided. The photodiode chip sequentially incudes, above a substrate, a grating layer and a ridge waveguide layer. The ridge waveguide layer includes multiple ridge waveguides. Each of the multiple ridge waveguides corresponds to one column of gratings in the multiple columns of gratings below. The grating layer includes multiple columns of gratings. At least two columns of gratings have different grating period pitches.

Abstract: A display module and a display device are provided. The display module includes a display panel, a flexible circuit board, and a printed circuit board. The display panel includes a bonding area. The flexible circuit board and the printed circuit board are electrically bonded and connected to the display panel in the bonding area, and are connected by a connector. The connector includes a first connection board and a second connection board. A side of the first connection board includes a groove including first pins. A side of the second connection board facing the first connection board includes second pins. The first pins and the second pins have a one-to-one correspondence. The second pins are plugged into the grooves, and are in contact with and electrically connected to the first pins; and a portion of at least one of the first pins is coated with a first insulating layer.

Abstract: Provided are a photoelectric chip, a manufacturing method and an installation method, which relate to the field of optical communication and transmission technologies. The chip is provided with a light-splitting groove (3), and the light-splitting groove (3) runs through an absorption layer (2) of the chip; the back of the chip is a light-entering side; the light-splitting groove (3) is configured to transmit and split out part (151) of incident light (15), and the other part (152) of the incident light (15) enters the absorption layer (2) for photovoltaic conversion. The photoelectric chip can split light and monitor optical power of the incident light.

Abstract: A quantum well structure, a method for processing a chip, and a chip are provided. The quantum well structure includes an indium aluminum arsenide (InAlAs) quantum well layer and an indium aluminum gallium arsenide (InAlGaAs) quantum well layer. The InAlAs quantum well layer is implemented as multiple InAlAs quantum well layers. The thickness of the InAlGaAs quantum well layer is the same as the thickness of the InAlAs quantum well layer. The InAlGaAs quantum well layer is disposed between two adjacent InAlAs quantum well layers. The thickness of the InAlAs quantum well layer ranges from 0.4 nm to 0.6 nm. The number of the multiple InAlAs quantum well layers ranges from 3 to 17.

Abstract: The present disclosure provides an siRNA nanocapsule and a preparation method and use thereof, relating to the technical field of biomedical engineering. The siRNA nanocapsule provided in the present disclosure includes siRNA and a shell encapsulating the siRNA and polymerized by a monomer A and a monomer B. The monomer A has a double bond at one end, and is electrostatically bound with the siRNA, and the monomer B includes molecules for improving tumor microenvironment sensitivity. The siRNA nanocapsule provided in the present disclosure is suitable for a wide range of clinical applications.

Abstract: Provided are a photodetector, a manufacturing method thereof, and a lidar system. A photosensitive region of the photodetector is circular and has a diameter range of 100-300 ?m. Compared with a conventional photodetector having a photosensitive region with a diameter of 50 ?m, the photodetector of the present invention can have a detection range greater than 200 m, responsivity greater than 20 A/W and a dark current less than 10 nA.

Abstract: A barcoded transposase complex and an application thereof in high-throughput sequencing. Provided is a transposase recognition element, having the following structure: X(m)Y(f)N(n), in which X(m) represents a transposase recognition region of a double-stranded nucleic acid structure, Y(f) represents a spacer region of a single-stranded DNA structure, and N(n) represents a sample barcode of a single-stranded DNA structure. The high-molecular-weight DNA is processed using the barcoded transposase complex, to obtain a lot of barcoded DNA fragments. The barcoded DNA fragments obtained from each high-molecular-weight DNA are mixed to obtain a mixing sample. A carrier having a molecular barcode is adopted to capture. An exonuclease is adopted for processing, and then transposase is released. StLFR technology is adopted to construct a DNA library. The barcoded transposase complex can be applied to hybrid sequencing of a high-throughput sequencing platform.

Abstract: The present disclosure relates to the field of ecological restoration of a coal gangue hill, and in particular, to a solid waste-based porous material, a method for preparing the solid waste-based porous material, and a method of ecological restoration of the coal gangue hill by applying the solid waste-based porous material. A coal-based solid waste restoration material and mycorrhizal solid bacterial agent are mixed to restore the coal gangue hill, the coal-based solid waste restoration material is prepared by mixing coal-based solid waste porous materials, low-rank coal, and waste organic matter and adding a microbial quickly decomposition agent for aerobic fermentation and standing.

Abstract: The disclosure provides a hybrid membrane camouflaged nanomedicine loaded with oxidative phosphorylation inhibitor and preparation method thereof. The nanomedicine comprises an inner core and an outer shell coated on the periphery of the inner core. The inner core is a ROS-responsive drug-loaded nanoparticle, and the drug loaded by the ROS-responsive nanocarrier is an oxidative phosphorylation inhibitor. The outer shell is a hybrid membrane of mitochondrial membrane and cancer cell membrane. The nanomedicines can cross the BBB and reach tumor sites by the homologous targeting of cancer cell membrane, and then they can homologously target and enter mitochondria by the mitochondrial membrane. Subsequently, under the high-level ROS environment of the mitochondria, the ROS responsive drug-loaded nanoparticle releases the oxidative phosphorylation inhibitor due to the swell and degradation of the inner core, so that the safe and efficient targeted GBM therapy is achieved.

Abstract: The present disclosure provides a gene editing nanocapsule and a preparation method and use thereof. The gene editing nanocapsule has a core-shell structure, wherein the inner core includes a Cas/sgRNA ribonucleoprotein complex, and the outer shell includes a polymer, the Cas/sgRNA ribonucleoprotein complex has a gene editing function, and the polymer acts as a carrier for the Cas/sgRNA ribonucleoprotein complex and protects it, because the polymer contains tumor microenvironment sensitive molecules, the nanocapsules can be efficiently released in tumor cells. Further, the surface of the outer shell can be modified with a targeting agent, so that the nanocapsule can specifically target tumor cells, which improves the endocytosis efficiency of the nanocapsule. The gene editing nanocapsule has good biocompatibility and biosafety, and is expected to become a safe and efficient gene therapy drug for tumors.

Abstract: The present disclosure relates to the field of ecological restoration of a coal gangue hill, and in particular, to a solid waste-based porous material, a method for preparing the solid waste-based porous material, and a method of ecological restoration of the coal gangue hill by applying the solid waste-based porous material. A coal-based solid waste restoration material and mycorrhizal solid bacterial agent are mixed to restore the coal gangue hill, the coal-based solid waste restoration material is prepared by mixing coal-based solid waste porous materials, low-rank coal, and waste organic matter and adding a microbial quickly decomposition agent for aerobic fermentation and standing.

Abstract: Provided are a photodetector, a manufacturing method thereof, and a lidar system. A photosensitive region of the photodetector is circular and has a diameter range of 100-300 ?m. Compared with a conventional photodetector having a photosensitive region with a diameter of 50 ?m, the photodetector of the present invention can have a detection range greater than 200 m, responsivity greater than 20 A/W and a dark current less than 10 nA.

Abstract: The present disclosure provides an siRNA nanocapsule and a preparation method and use thereof, relating to the technical field of biomedical engineering. The siRNA nanocapsule provided in the present disclosure includes siRNA and a shell encapsulating the siRNA and polymerized by a monomer A and a monomer B. The monomer A has a double bond at one end, and is electrostatically bound with the siRNA, and the monomer B includes molecules for improving tumor microenvironment sensitivity. The siRNA nanocapsule provided in the present disclosure is suitable for a wide range of clinical applications.

Abstract: Provided are a photoelectric chip, a manufacturing method and an installation method, which relate to the field of optical communication and transmission technologies. The chip is provided with a light-splitting groove (3), and the light-splitting groove (3) runs through an absorption layer (2) of the chip; the back of the chip is a light-entering side; the light-splitting groove (3) is configured to transmit and split out part (151) of incident light (15), and the other part (152) of the incident light (15) enters the absorption layer (2) for photovoltaic conversion. The photoelectric chip can split light and monitor optical power of the incident light.

Abstract: Disclosed in the present disclosure is a biodegradable amphiphilic polymer containing disulfide in the side chain, a self-crosslinked polymeric vesicle thereof and an application in the targeted therapy of lung cancer. The polymer is obtained by an activity-controllable ring-opening polymerization based on a cyclic carbonate monomer containing a functional group of dithiolane ring, which has a controllable molecular weight and a narrow molecular weight distribution, and does not require processes of protection and deprotection; the polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer of the present disclosure has biodegradability and can be used to control the drug release system, the prepared lung cancer-targeted reduction-sensitive reversibly-crosslinked polymeric vesicle as a nanomedicine carrier supports stable long circulation in vivo.

Abstract: Disclosed in the present disclosure is a biodegradable amphiphilic polymer containing disulfide in the side chain, a self-crosslinked polymeric vesicle thereof and an application in the targeted therapy of lung cancer. The polymer is obtained by an activity-controllable ring-opening polymerization based on a cyclic carbonate monomer containing a functional group of dithiolane ring, which has a controllable molecular weight and a narrow molecular weight distribution, and does not require processes of protection and deprotection; the polymer obtained by the ring-opening polymerization of the cyclic carbonate monomer of the present disclosure has biodegradability and can be used to control the drug release system, the prepared lung cancer-targeted reduction-sensitive reversibly-crosslinked polymeric vesicle as a nanomedicine carrier supports stable long circulation in vivo.

Abstract: The present invention provides compounds of Formula (I): or stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, wherein all the variables are as defined herein. These compounds are selective ROCK inhibitors. This invention also relates to pharmaceutical compositions comprising these compounds and methods of treating cardiovascular, smooth muscle, oncologic, neuropathologic, autoimmune, fibrotic, and/or inflammatory disorders using the same.

Abstract: The disclosure relates to a cyclic carbonate monomer containing double iodine, a biodegradable polymer prepared thereby and use. The polymer can be obtained by ring-opening polymerization of the cyclic carbonate monomer containing double iodine, without affecting the ring-opening polymerization and without a protection and deprotection process. The polymer which is obtained by ring-opening polymerization of the cyclic carbonate monomer of the present disclosure can be assembled into a nano-vesicle and a micelle as a drug carrier, a biological tissue scaffold or a CT contrast media.