Patents by Inventor Yanan GUO

Yanan GUO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240383992
    Abstract: A chimeric antigen receptor (CAR), containing a BCMA (B cell maturation antigen) binding domain. The BCMA binding domain includes an antibody or an antigen-binding fragment of an antibody that specifically binds to BCMA. The antibody contains a heavy-chain complementarity determining region 3 (HCDR3), a heavy-chain complementarity determining region 2 (HCDR2), and a heavy-chain complementarity determining region 1 (HCDR1). The HCDR3 contains an amino acid sequence as set forth in SEQ ID NO: 25, the HCDR2 contains an amino acid sequence as set forth in SEQ ID NO: 41, and the HCDR1 contains an amino acid sequence as set forth in SEQ ID NO: 21.
    Type: Application
    Filed: April 26, 2022
    Publication date: November 21, 2024
    Applicant: ORICELL THERAPEUTICS CO., LTD.
    Inventors: Siye CHEN, Yanhong XU, Hao GUO, Yue YANG, Huijiao LI, Zhifeng XU, Yanan SUN, Huanfeng YANG, Xiaowen HE
  • Patent number: 12134653
    Abstract: This disclosure relates to anti-CD40 (TNF Receptor Superfamily Member 5) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: September 8, 2021
    Date of Patent: November 5, 2024
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen, Jingshu Xie
  • Publication number: 20240352141
    Abstract: This disclosure relates to anti-human OX40 (TNF Receptor Superfamily Member 4, or TNFRSF4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: April 24, 2024
    Publication date: October 24, 2024
    Inventors: Yi Yang, Yanan Guo, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni
  • Publication number: 20240343806
    Abstract: This disclosure relates to anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4 or CTLA-4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: June 20, 2024
    Publication date: October 17, 2024
    Inventors: Yi Yang, Yanan Guo, Xiaodong Cheng, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni
  • Publication number: 20240333204
    Abstract: A tracking type flexible photovoltaic bracket is provided, including photovoltaic assemblies, pillars, a driving member, direction-changing mechanisms, and two pulling ropes. Each of the pillars is disposed with a double-rope grooved wheel. The driving member is configured to drive the double-rope grooved wheel arranged on an end of the driving member to rotate. The direction-changing mechanisms are arranged corresponding ones of the pillars in one-to-one manner. Each of the direction-changing mechanisms includes a worm gear assembly and a curved plate assembly. Each of the corresponding ones of the pillars is rotatably connected with the worm gear assembly and the curved plate assembly, and a bottom of the curved plate assembly is disposed with a gear rack. First ends and second ends of the two pulling ropes are wound on the respective double-rope grooved wheels being respectively located on the first ends and the second ends.
    Type: Application
    Filed: April 27, 2023
    Publication date: October 3, 2024
    Inventors: Ying HUANG, Yanfei ZHU, Yanan GUO
  • Publication number: 20240311558
    Abstract: A media item of a content sharing platform is identified. A subset of comments in a comment section presented with the media item is identified. A comment score for each comment in the subset of comment is determined. The comment score indicates comment attributes associated with a respective comment in the subset of comments. At least one comment section score for the media item is determined based on comment scores of the subset of comments. One or more media item attributes of the media item are determined based on the at least one comment section score. The media item is associated with the one or more media item attributes. The media one or more media item attributes are indicative of whether a ranking of the media item is to be adjusted.
    Type: Application
    Filed: March 13, 2023
    Publication date: September 19, 2024
    Inventors: Mason Henry DiMarco, Shuo Guo, Yanan Qian
  • Patent number: 12054547
    Abstract: This disclosure relates to anti-cytotoxic T-lymphocyte-associated protein 4 (CTLA4 or CTLA-4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: August 6, 2024
    Assignee: Eucure (Beijing) Biopharma Co., Ltd.
    Inventors: Yi Yang, Yanan Guo, Xiaodong Cheng, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni
  • Patent number: 12016315
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD3e (T-cell surface glycoprotein CD3 epsilon chain), and methods of use thereof.
    Type: Grant
    Filed: February 5, 2021
    Date of Patent: June 25, 2024
    Assignees: Biocytogen Pharmaceuticals (Beijing) Co., Ltd., Biocytogen JiangSu Co., Ltd.
    Inventors: Yuelei Shen, Yanan Guo, Rui Huang, Xiaofei Zhou, Yang Bai, Jiawei Yao, Chaoshe Guo
  • Patent number: 11999790
    Abstract: This disclosure relates to anti-human OX40 (TNF Receptor Superfamily Member 4, or TNFRSF4) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: June 4, 2024
    Assignee: Eucure (Beijing) Biopharma Co., Ltd
    Inventors: Yi Yang, Yanan Guo, Yunyun Chen, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Xiaodong Cheng, Yuelei Shen, Jian Ni
  • Publication number: 20240092922
    Abstract: This disclosure relates to anti-TNFRSF9 (tumor necrosis factor receptor superfamily member 9) antibodies, antigen-binding fragments, and the uses thereof.
    Type: Application
    Filed: September 11, 2023
    Publication date: March 21, 2024
    Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen
  • Publication number: 20230417834
    Abstract: The invention discloses a method, a system and a storage medium for solid-phase concentration correction of a lithium battery.
    Type: Application
    Filed: June 12, 2023
    Publication date: December 28, 2023
    Inventors: Pingchao Hao, Zhiyi Zhang, Yanan Guo, Xiao Yan, Enhai Zhao, Zhou Yang, Zhimin Zhou, Xiaohua Chen
  • Publication number: 20230363362
    Abstract: This disclosure relates to genetically modified animal expressing human or chimeric (e.g., humanized) GLP1R, and methods of use thereof.
    Type: Application
    Filed: September 17, 2021
    Publication date: November 16, 2023
    Inventors: Yuelei Shen, Jiawei Yao, Yanan Guo, Yang Bai, Chengzhang Shang
  • Publication number: 20230361593
    Abstract: The invention provides method, apparatus and storage medium for adjusting the charging-discharging efficiency ratio of an energy storage power station.
    Type: Application
    Filed: April 26, 2023
    Publication date: November 9, 2023
    Inventors: Pei Song, Zhiyi Zhang, Yanan Guo, Danfei Gu, Pingchao Hao, Peng Ding, Weikun Wu, Guopeng Zhou, Wenfu Wang, Xiao Yan, Enhai Zhao, Xiaohua Chen
  • Patent number: 11723348
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD47, and methods of use thereof.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: August 15, 2023
    Assignee: Biocytogen Pharmaceuticals (Beijing) Co., Ltd.
    Inventors: Yuelei Shen, Yang Bai, Jian Ni, Rui Huang, Chengzhang Shang, Yanan Guo
  • Publication number: 20230227531
    Abstract: The present disclosure relates to genetically modified non-human animals that express a fusion protein including B2M and FcRn, and methods of use thereof. In some embodiments, the animals can have a B-NDG background. In some embodiments, the endogenous B2M gene is knocked out in the animals.
    Type: Application
    Filed: June 18, 2021
    Publication date: July 20, 2023
    Inventors: Yuelei Shen, Jiawei Yao, Yanan Guo, Yang Bai, Chengzhang Shang
  • Publication number: 20230165227
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD276, and methods of use thereof.
    Type: Application
    Filed: May 21, 2021
    Publication date: June 1, 2023
    Inventors: Yuelei Shen, Yang Bai, Jiawei Yao, Yanan Guo, Lei Zhao
  • Publication number: 20230148574
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) CD38, and methods of use thereof.
    Type: Application
    Filed: April 1, 2021
    Publication date: May 18, 2023
    Inventors: Yuelei Shen, Yang Bai, Jiawei Yao, Yanan Guo, Lei Zhao
  • Publication number: 20230072216
    Abstract: The present disclosure relates to genetically modified non-human animals that express a human or chimeric (e.g., humanized) major histocompatibility complex (MHC) protein complex, and methods of use thereof.
    Type: Application
    Filed: January 8, 2021
    Publication date: March 9, 2023
    Inventors: Yuelei Shen, Chaoshe Guo, Meiling Zhang, Rui Huang, Yanan Guo, Yang Bai, Jiawei Yao, Chengzhang Shang
  • Publication number: 20230058049
    Abstract: This disclosure relates to genetically modified immunodeficient animals which express a human or chimeric (e.g., humanized) SIRP? and/or human or chimeric (e.g., humanized) CD47, and methods of use thereof.
    Type: Application
    Filed: December 31, 2020
    Publication date: February 23, 2023
    Inventors: Yuelei Shen, Yang Bai, Jiawei Yao, Chaoshe Guo, Meiling Zhang, Rui Huang, Yanan Guo, Chengzhang Shang
  • Publication number: 20230043907
    Abstract: Provided are a humanized transgenic non-human animal, especially a rodent, in particular a transgenic mouse containing a human interleukin 17A (IL-17A) gene, a human gene 17RA (IL-17RA) and/or a human TNF-alpha gene, and a preparation method therefor and the use thereof.
    Type: Application
    Filed: August 1, 2022
    Publication date: February 9, 2023
    Inventors: Yuelei Shen, Chaoshe Guo, Yanan Guo, Yang Bai, Rui Huang, Lei Zhao, Xiaofei Zhou, Meiling Zhang, Jiawei Yao