Patents by Inventor Yanan Hua

Yanan Hua has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • B7-H3 ANTIBODY AND USE THEREOF
    Publication number: 20240343809
    Abstract: A B7-H3 antibody and a use thereof are provided. The heavy chain complementarity determining regions of the B7-H3 antibody include the amino acid sequences shown in SEQ ID NOs. 6-8, and the light chain complementarity determining regions of the B7-H3 antibody include the amino acid sequences shown in SEQ ID NOs. 14-16. The B7-H3 antibody can bind to a B7-H3 antigen and/or cells expressing the B7-H3 antigen. A B7-H3×CD3 bispecific antibody is constructed by using the B7-H3 antibody.
    Type: Application
    Filed: July 19, 2022
    Publication date: October 17, 2024
    Inventors: Wenjun ZHANG, Min LIU, Wenwu TIAN, Feng LI, Yanan HUA
  • Bispecific Antibody, Preparation Method Therefor and Application Thereof
    Publication number: 20220324993
    Abstract: Provided are a bispecific antibody and a preparation method therefor. The antibody comprises structural domains capable of binding to CD20 and CD3, and a heterodimer Fc region. The structural domains capable of binding to CD20 and CD3 are each independently selected from a Fab region, a ScFv region, or an sDab region. The bispecific antibody targets CD20 and CD3, and mediates T cell-specific killing of tumor cells.
    Type: Application
    Filed: December 17, 2019
    Publication date: October 13, 2022
    Inventors: Wenjun Zhang, Feng Li, Yanan Hua, Jiaxi Liu, Chunhua Fang