Patents by Inventor Yanan LU

Yanan LU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11986575
    Abstract: A preparation method of drug-loaded micelles of an absorbable vascular stent coating for angiostenosis in an infant is provided, including the following steps: S1: dissolving a drug to be encapsulated in an appropriate amount of an emulsifying agent, adding a chitosan-poly(p-dioxohone) amphiphilic block copolymer (chitosan-b-PPDO copolymer), and thoroughly mixing to obtain a drug-copolymer solution; S2: adding the drug-copolymer solution obtained in S1 dropwise to an emulsifying agent aqueous solution prepared in advance, and continuously stirring to obtain a stable drug-loaded micellar solution; and S3: removing the emulsifying agent from the micellar solution obtained in S2 through vacuum evaporation, stirring a resulting concentrate, and centrifuging the concentrate to obtain a supernatant; and filtering the supernatant to obtain a filtrate, and subjecting the filtrate to dialysis to obtain the drug-loaded micelles.
    Type: Grant
    Filed: March 29, 2022
    Date of Patent: May 21, 2024
    Assignee: XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Kun Sun, Jing Sun, Sun Chen, Kai Bai, Yanan Lu, Lu Wang, Fujun Wang, Fan Zhao, Jihong Huang
  • Publication number: 20240042109
    Abstract: A preparation method of drug-loaded micelles of an absorbable vascular stent coating for angiostenosis in an infant is provided, including the following steps: Si: dissolving a drug to be encapsulated in an appropriate amount of an emulsifying agent, adding a chitosan-poly(p-dioxohone) amphiphilic block copolymer (chitosan-b-PPDO copolymer), and thoroughly mixing to obtain a drug-copolymer solution; S2: adding the drug-copolymer solution obtained in S1 dropwise to an emulsifying agent aqueous solution prepared in advance, and continuously stirring to obtain a stable drug-loaded micellar solution; and S3: removing the emulsifying agent from the micellar solution obtained in S2 through vacuum evaporation, stirring a resulting concentrate, and centrifuging the concentrate to obtain a supernatant; and filtering the supernatant to obtain a filtrate, and subjecting the filtrate to dialysis to obtain the drug-loaded micelles.
    Type: Application
    Filed: March 29, 2022
    Publication date: February 8, 2024
    Applicant: XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
    Inventors: Kun SUN, Jing SUN, Sun CHEN, Kai BAI, Yanan LU, Lu WANG, Fujun WANG, Fan ZHAO, Jihong HUANG
  • Patent number: 11413219
    Abstract: An automatic breastfeeding method of a premature infant is disclosed, which includes a preparation stage, an active lactation stage, a passive lactation stage and a rest stage. The invention also provides an automatic breastfeeding machine used for the automatic breastfeeding method of a premature infant, comprising a stomach tube, a lactation supply device, a detector and a control device. According to the invention, a self-sucking ability of the premature infant is trained, normal circulation of a mouth-pharyngeal-gastric-intestinal reflex of the premature infant is realized, and nutritional requirements of the premature infant are ensured in the case of taking differences of the premature infants into account, so that the premature infants have no difference with term infants in care, diet, neurological development and growth and development in the future.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: August 16, 2022
    Assignee: SHENZHEN KAIYANG INDUSTRIAL CO., LTD.
    Inventors: Hongping Li, Xinyong Chen, Xikai Yang, Yanan Lu, Weimin Huang
  • Patent number: 11366970
    Abstract: A semantic analysis method includes: inputting a word vector of each word in each sample sentence in a dialog flow into an encoder model, to obtain a sentence vector representing semantics of the sample sentence; inputting the sentence vector into a first decoder model corresponding to each context sentence of the sample sentence and a second decoder model corresponding to each word of the sample sentence, to obtain a first identifier corresponding to the context sentence and a second identifier corresponding to the word; obtaining a probability of the first identifier and a probability of the second identifier, and determining a value of a target function; performing parameter training on the encoder model according to the value of the target function; and inputting a word vector of each word in a test sentence into the trained encoder model, to obtain a sentence vector representing semantics of the test sentence.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: June 21, 2022
    Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITED
    Inventors: Yanan Lu, Rongyu Cao, Fen Lin
  • Publication number: 20210388065
    Abstract: The present invention provides recombinant monoclonal antibodies that bind to the Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2 or COVID-19) spike protein, and methods of use. In various embodiments of the invention, the antibodies are fully human antibodies that bind to SARS-CoV-2 spike protein. In some embodiments, the antibodies of the invention are useful for inhibiting or neutralizing SARS-CoV-2 activity, thus providing a means of treating or preventing COVID-19 infection in humans. In some embodiments, the invention provides for a combination of one or more antibodies that bind to the SARS-CoV-2 spike protein for use in treating COVID-19 infection. In certain embodiments, the one or more antibodies bind to distinct non-competing epitopes comprised in the receptor binding domain of the SARS-CoV-2 spike protein.
    Type: Application
    Filed: April 15, 2020
    Publication date: December 16, 2021
    Applicants: ACTIVE MOTIF SHANGHAI LIMITED, SHANGHAI PUBLIC HEALTH CLINICAL CENTER, FUDAN UNIVERSITY, SHANGHAI PUBLIC HEALTH CLINICAL CENTER
    Inventors: Yanan LU, Fei LAN, Jianqing XU, Xi ZHAO, Longfei DING, Yongheng WANG, Jinkai WAN, Shenghui XING, Joseph FERNANDEZ
  • Publication number: 20200253832
    Abstract: An automatic breastfeeding method of a premature infant is disclosed, which includes a preparation stage, an active lactation stage, a passive lactation stage and a rest stage. The invention also provides an automatic breastfeeding machine used for the automatic breastfeeding method of a premature infant, comprising a stomach tube, a lactation supply device, a detector and a control device. According to the invention, a self-sucking ability of the premature infant is trained, normal circulation of a mouth-pharyngeal-gastric-intestinal reflex of the premature infant is realized, and nutritional requirements of the premature infant are ensured in the case of taking differences of the premature infants into account, so that the premature infants have no difference with term infants in care, diet, neurological development and growth and development in the future.
    Type: Application
    Filed: January 11, 2018
    Publication date: August 13, 2020
    Inventors: Hongping LI, Xinyong CHEN, Xikai YANG, Yanan LU, Weimin HUANG
  • Publication number: 20200130065
    Abstract: A method for producing a water-atomized prealloyed powder with high cold press formability, includes the following steps: (a) preparing a ?400 mesh semi-finished prealloyed powder; (b) controlling the semi-finished prealloyed powder to have a moisture content of 1 wt % to 2 wt % and an oxygen content of 0.6 wt % to 0.8 wt %, and then drying in a vacuum drying oven at 100° C. for 90 minutes to 120 minutes, so that a preliminary bond is produced between powder particles; and (c) reducing, annealing, crushing, and sieving an initially bonded powder particle. The powder is changed from a spheroidal shape to more complex shapes such as “rice ear shape”, “grape shape”, and “satellite powder”, which greatly improves the cold press formability of the prealloyed powder; the method only performs simple surface modification of the powder without changing other properties, and has wide applicability.
    Type: Application
    Filed: December 17, 2019
    Publication date: April 30, 2020
    Inventors: Xiaofeng LI, Anding FAN, Dagen DOU, Yanan LU, Wenwen AN
  • Publication number: 20200065389
    Abstract: A semantic analysis method includes: inputting a word vector of each word in each sample sentence in a dialog flow into an encoder model, to obtain a sentence vector representing semantics of the sample sentence; inputting the sentence vector into a first decoder model corresponding to each context sentence of the sample sentence and a second decoder model corresponding to each word of the sample sentence, to obtain a first identifier corresponding to the context sentence and a second identifier corresponding to the word; obtaining a probability of the first identifier and a probability of the second identifier, and determining a value of a target function; performing parameter training on the encoder model according to the value of the target function; and inputting a word vector of each word in a test sentence into the trained encoder model, to obtain a sentence vector representing semantics of the test sentence.
    Type: Application
    Filed: November 1, 2019
    Publication date: February 27, 2020
    Inventors: Yanan LU, Rongyu CAO, Fen LIN