Abstract: Provided is a heat transfer composition, which is characterized in that the heat transfer composition comprises the following three components: 1,1,1,2-tetrafluoroethane (R134a) with a mass ratio of 28%-46%, 2,3,3,3-tetrafluoropropene (R1234yf) with a mass ratio of 33%-71%, and trans 1,3,3,3-tetrafluoropropene (R1234ze(E)) with a mass ratio of I %-23%. The described heat transfer composition which replaces R134a not only has the environmentally friendly features of having low GWP and zero ODP, but also has excellent thermal performance. When applied in a centrifugal chiller, the volumetric refrigeration capacity and energy efficiency are equivalent to those of a centrifugal unit using an R134a refrigerant, and the slip in temperature is small; thus, the present application may become a heat transfer composition to replace R134a.