Patents by Inventor Yanfang Guan

Yanfang Guan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Low-frequency mutations enrichment sequencing method for free target DNA in plasma
    Patent number: 11001837
    Abstract: The present invention provides a low-frequency mutation enrichment sequencing method for free target DNA in plasma, comprising plasma DNA extraction and library construction, general library TT COLD PCR amplification enrichment, probe enrichment capture, PCR and sequencing of captured products, and positive and negatice double-strand error-correction low-frequency information analysis.
    Type: Grant
    Filed: February 18, 2016
    Date of Patent: May 11, 2021
    Assignee: Geneplus—Beijing
    Inventors: Xiaoxing Lv, Xin Yi, Meiru Zhao, Yanfang Guan, Tao Liu, Ling Yang
  • ANALYSIS SYSTEM FOR PERIPHERAL BLOOD-BASED NON-INVASIVE DETECTION OF LESION IMMUNE REPERTOIRE DIVERSITY AND USES OF SYSTEM
    Publication number: 20200199650
    Abstract: A method for analyzing the diversity of immune repertoire of T cell receptors (TCR) or B cell receptors (BCR) of a cell-free DNA (cf-DNA) sample and of a nuclear DNA sample of peripheral blood mononuclear cell (PBMC), applicable in screening and determining the presence of lesion-infiltrating lymphocytes.
    Type: Application
    Filed: May 18, 2017
    Publication date: June 25, 2020
    Inventors: Yuqi Wang, Yanfang Guan, Xin Yi, Tao Liu, Linjun Wu, Ling Yang
  • LOW-FREQUENCY MUTATIONS ENRICHMENT SEQUENCING METHOD FOR FREE TARGET DNA IN PLASMA
    Publication number: 20180371453
    Abstract: The present invention provides a low-frequency mutation enrichment sequencing method for free target DNA in plasma, comprising plasma DNA extraction and library construction, general library TT COLD PCR amplification enrichment, probe enrichment capture, PCR and sequencing of captured products, and positive and negatice double-strand error-correction low-frequency information analysis.
    Type: Application
    Filed: February 18, 2016
    Publication date: December 27, 2018
    Applicant: Geneplus - Beijing
    Inventors: Xiaoxing Lv, Xin Yi, Meiru Zhao, Yanfang Guan, Tao Liu, Ling Yang