Abstract: The disclosure discloses a preparation method of a composite coating for a resin matrix composite, comprising the following steps: preparing ceramic-resin composite powders which comprise Al2O3 ceramic, a thermosetting resin and a curing agent and are semi-thermosetting resin powders; and respectively spraying pure Al2O3 ceramic powders and the composite powders on the surface of the resin matrix composite by supersonic atmospheric plasma spraying to form a ceramic-resin composite coating, wherein the pure Al2O3 ceramic powders are fed into jet flow in a manner of feeding powder inside a spray gun, and the composite powders are fed into jet flow in a manner of feeding powder outside the spray gun. Correspondingly, the disclosure also provides a preparation device of a composite coating for a resin matrix composite.

Abstract: Disclosed is a fastening structure for a seating foam, comprising a foam and a reinforcement fabric, and characterized in that the fastening structure is directly provided at a reinforcement fabric at a location corresponding to a fastening position, and is connected to the reinforcement fabric. The fastening structure of the present invention simultaneously meets two functional requirements of a foam, namely reinforcement of a side B of the foam and fastening of an exterior side A of the foam. The novel fastening structure of the present invention saves space, is thin and light, enhances the strength of the foam against a pull-out force, and optimizes a foam production process.

Abstract: Disclosed herein are methods of treatment comprising administering a therapeutically effective amount of a myosin modulator or a pharmaceutically acceptable salt thereof to a subject in need thereof and diagnostic methods useful in connection with those treatments. Due to observations unfolding in clinical trials with mavacamten and with mavacamten and other myosin inhibitors in the pre-clinical setting, new insights into how myosin inhibitors can be used beneficially to impact the disease state of HCM and other diseases are provided herein.

Abstract: Provided are a silicon-on-insulator structure having bipolar stress and a manufacturing method therefor. The manufacturing method comprises providing a composite substrate, wherein the composite substrate has a silicon substrate layer, a buried oxide layer and a silicon-on-insulator layer sequentially from bottom to top, epitaxially growing a silicon germanium layer on an upper surface of the silicon-on-insulator layer; depositing a hard mask layer to cover a portion of the silicon germanium layer corresponding to an N-type MOS transistor region; depositing a surface oxide layer to cover the silicon germanium layer and the hard mask layer; performing a high temperature annealing treatment so that a portion of the silicon-on-insulator layer corresponding to a P-type MOS transistor region is converted into a silicon-germanium-on-insulator layer, and the portion corresponding to the N-type MOS transistor region is converted into a tensile stress silicon-on-insulator layer.

Abstract: Provided are a silicon-on-insulator structure having bipolar stress and a manufacturing method therefor. The manufacturing method comprises providing a composite substrate, wherein the composite substrate has a silicon substrate layer, a buried oxide layer and a silicon-on-insulator layer sequentially from bottom to top, epitaxially growing a silicon germanium layer on an upper surface of the silicon-on-insulator layer; depositing a hard mask layer to cover a portion of the silicon germanium layer corresponding to an N-type MOS transistor region; depositing a surface oxide layer to cover the silicon germanium layer and the hard mask layer; performing a high temperature annealing treatment so that a portion of the silicon-on-insulator layer corresponding to a P-type MOS transistor region is converted into a silicon-germanium-on-insulator layer, and the portion corresponding to the N-type MOS transistor region is converted into a tensile stress silicon-on-insulator layer.

Abstract: The present invention provides a method for treating osteoarthritis in a mammal, comprising administering to a mammal in need thereof, an effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt or solvate thereof.