Abstract: A microneedle patch, including: a substrate layer and a first microneedle provided on the substrate layer; wherein the number of the first microneedle is at least one, the first microneedle includes a microneedle body and at least one protrusion provided on the microneedle body; and the each protrusion extends in a radial direction of the first microneedle from a needle tip to the substrate layer, and has a tip end away from the microneedle body.

Abstract: A spliced display screen and a spliced display device are provided. The spliced display screen includes gate driving units arranged within pixel units to drive these pixel units, eliminating the need for binding scan chips. This approach can reduce the number of side wirings and binding terminals, thereby improving the yield of the spliced display screen. Additionally, by placing both scan terminals and data terminals on the same side of the display area, the display panel is designed with connecting terminals on only one side, effectively eliminating a border on one side of a display panel. Moreover, a terminal area of one display panel is arranged corresponding to the display area of another display panel, and therefore, a splicing seam is minimized or even eliminated.

Abstract: A display panel, a manufacturing method thereof, and a display device are provided. The display panel includes a driving substrate, a first light-emitting device layer disposed on a side of the driving substrate, and a second light-emitting device layer disposed on a side the driving substrate away from the first light-emitting device layer. The first light-emitting device layer includes a plurality of first light-emitting devices. The second light-emitting device layer includes a plurality of second light-emitting devices. The driving substrate includes a plurality of driving thin-film transistors. A driving thin-film transistor is connected to a first light-emitting device and a second light-emitting device. The first light-emitting device layer and the second light-emitting device layer are respectively disposed on two sides of the driving substrate.

Abstract: The present disclosure provides a C6?-substituted locked nucleic acid-modified cap analog and a use thereof, wherein the cap analog improves the stability of mRNA and/or the translation efficiency of mRNA.

Abstract: A display panel, a spliced display module, and a method of manufacturing the spliced display module are provided. The display panel includes a first display area and a second display area located at a periphery of the first display area at least in a first direction. A first pixel group is arranged in the second display area and includes a first light-emitting assembly, a first driving assembly, a second driving assembly, and a second light-emitting assembly that are sequentially arranged in the first direction.

Abstract: The present disclosure belongs to the technical field of mRNA vaccines, and specifically relates to a herpes zoster mRNA vaccine, a preparation method therefor, and a use thereof. The herpes zoster mRNA vaccine provided by the present disclosure comprises an RNA encoding a varicella-zoster virus gE glycoprotein or a variant thereof. The vaccine can prevent herpes zoster infection and its complications.

Abstract: The present disclosure belongs to the technical field of mRNA vaccines, and specifically relates to a herpes zoster mRNA vaccine, a preparation method therefor, and a use thereof. The herpes zoster mRNA vaccine provided by the present disclosure comprises an RNA encoding a varicella-zoster virus gE glycoprotein or a variant thereof. The vaccine can prevent herpes zoster infection and its complications.

Abstract: A planar microneedle includes a base layer, and microneedle(s) including a needle tip, a middle part, and a needle base. The microneedle further includes a first side-wall located on the same plane as the base layer, a circumferential side-wall, and a third side-wall, the first side-wall and the circumferential side-wall being located circumferentially around the microneedle, and the third side-wall being located at the bottom of the microneedle. The third side-wall includes a first edge connected with the base layer, and a movable edge. The microneedle is rotated around the first edge until an angle between the third side-wall and the plane where the base layer is located is 0°-±10°, and a base through-hole is formed at the junction of the microneedle and the base layer. A microneedle patch, a planar microneedle manufacturing device, a planar microneedle preparation method, and a planar microneedle standing device are provided.

Abstract: The present disclosure provides a C6?-substituted locked nucleic acid-modified cap analog and a use thereof, wherein the cap analog improves the stability of mRNA and/or the translation efficiency of mRNA.

Abstract: A display panel and a manufacturing method thereof, and an electronic terminal are provided and including a driving circuit layer, a planarization layer, an electrode layer, and a light-emitting layer which are stacked from bottom to top. The driving circuit layer includes driving circuits. The planarization layer includes first planarization portions and second planarization portions which are arranged in a same layer. The electrode layer includes electrode groups. The light-emitting layer includes light-emitting devices. The first planarization portion is disposed on a side of the driving circuit close to the electrode layer, and the second planarization portion is disposed on a side of one of the electrode group close to the driving circuit layer. A thickness of the second planarization portion is greater than a thickness of the first planarization portion.

Abstract: A manufacturing method of a display panel and a spliced display panel are provided, wherein the manufacturing method of a display panel includes the following steps: at least forming a silver nanowire layer on a lateral end surface of a substrate to be processed. An ultraviolet laser is used to sinter the silver nanowire layer. The silver nanowire layer is patterned to form multiple connection wires connected between the first connection terminal and the corresponding second connection terminal. The configuration prevents insufficiently tight or poor contact between silver nanowires.

Abstract: A spliced display screen and a spliced display device are provided. The spliced display screen includes gate driving units arranged within pixel units to drive these pixel units, eliminating the need for binding scan chips. This approach can reduce the number of side wirings and binding terminals, thereby improving the yield of the spliced display screen. Additionally, by placing both scan terminals and data terminals on the same side of the display area, the display panel is designed with connecting terminals on only one side, effectively eliminating a border on one side of a display panel. Moreover, a terminal area of one display panel is arranged corresponding to the display area of another display panel, and therefore, a splicing seam is minimized or even eliminated.

Abstract: A driving backplane and a display panel are provided. The driving backplane includes a substrate, a driving circuit layer, a protective layer, and pads. The driving circuit layer is disposed on a side of the substrate, and its top forms a first height with a bottom of the substrate. The protective layer is disposed on a side of the driving circuit layer facing away from the substrate, and includes first protective layer structures. Each first protective layer structure corresponds to each pad area. The pads are formed on sides of the first protective layer structures facing away from the driving circuit layer, each pad is connected to the driving circuit layer through a via hole in each first protective layer structure, and a top of one first protective layer structure forms a second height with the bottom of the substrate, and the second height is greater than the first height.

Abstract: A display panel and a display module are provided. The display panel includes a first base, a black matrix layer, and a color resist layer, wherein the black matrix layer includes a plurality of openings, the color resist layer is disposed above the first base and filled in the plurality of openings. A light reflectivity of a side of the black matrix layer away from the first base is greater than a light reflectivity of a side of the black matrix layer close to the first base.

Abstract: A display panel, a manufacturing method thereof, and a display device are provided. The display panel includes a driving substrate, a first light-emitting device layer disposed on a side of the driving substrate, and a second light-emitting device layer disposed on a side the driving substrate away from the first light-emitting device layer. The first light-emitting device layer includes a plurality of first light-emitting devices. The second light-emitting device layer includes a plurality of second light-emitting devices. The driving substrate includes a plurality of driving thin-film transistors. A driving thin-film transistor is connected to a first light-emitting device and a second light-emitting device. The first light-emitting device layer and the second light-emitting device layer are respectively disposed on two sides of the driving substrate.

Abstract: A display panel and a manufacturing method thereof, and an electronic terminal are provided and including a driving circuit layer, a planarization layer, an electrode layer, and a light-emitting layer which are stacked from bottom to top. The driving circuit layer includes driving circuits. The planarization layer includes first planarization portions and second planarization portions which are arranged in a same layer. The electrode layer includes electrode groups. The light-emitting layer includes light-emitting devices. The first planarization portion is disposed on a side of the driving circuit close to the electrode layer, and the second planarization portion is disposed on a side of one of the electrode group close to the driving circuit layer. A thickness of the second planarization portion is greater than a thickness of the first planarization portion.

Abstract: The invention relates to the technical field of nuclear reactor materials, in particular to a processing method for improving the corrosion resistance of iron and steel materials in lead or lead-bismuth, comprising the following steps: selecting iron and steel materials containing Mn and Cr elements, using high-energy fast neutrons generated by fission as the radiation source, and performing irradiation on the iron and steel material so that Mn and Cr elements diffuse to the surface of the iron and steel material to form a dense oxide film, so as to complete the improvement of the corrosion resistance of the iron and steel material. The invention enhances the formation of the dense-structured oxide layer by irradiation. The oxide layer has good protection and self-healing properties in irradiation environment, and a new solution is proposed for enhancing the corrosion resistance of steel in lead and lead-bismuth coolant fast reactors.

Abstract: Disclosed herein are compositions and methods for programming a cell. The compositions include a substrate and a cell adhesion agent. The substrate includes a surface having a micropatterned object and the cell adhesion agent is immobilized within a first area defined by the micropatterned object.