Abstract: Disclosed are inhibitors of mevalonate pathway as an efficient vaccine adjuvant and use thereof. In particular, the inhibitor is an acetoacetyl-CoA transferase inhibitor, a HMG-CoA synthase inhibitor, a HMG-CoA reductase inhibitor, a mevalonate kinase inhibitor, a phosphomevalonate kinase inhibitor, a mevalonate-5-pyrophosphate decarboxylase inhibitor, an isopentenyl pyrophosphate isomerase inhibitor, a farnesyl pyrophosphate synthase inhibitor, a geranylgeranyl pyrophosphate synthase inhibitor or a geranylgeranyl transferase (I, II) inhibitor. Also disclosed is an immunogenic composition comprising inhibitors of mevalonate to pathway as an adjuvant.

Abstract: A surface treatment method of metallic materials provided by the present invention includes steps of: (S1) cleaning a surface of an initial metallic material to be treated, and then drying; and (S2) placing the dried metallic material in a heating furnace, adjusting a vacuum degree inside the heating furnace to a preset value under the protection of a mixed flowing gas of oxygen and an inert gas, heating and preserving, cooling to room temperature by furnace cooling, and completing the surface treatment of the metallic material to be treated, wherein the heating temperature is larger than the destruction temperature of the native oxide at the surface of the initial metallic material. The present invention is able to increase the surface hardness of the metallic material within a large depth, and has the advantages of low processing cost, high efficiency, good controllability, convenient operation and low surface contamination for the workpiece.

Abstract: A wire substrate, a display device including a wire substrate, and a method of fabricating a wire substrate are disclosed. The display device comprises: a first base; and a first wiring layer disposed on the first base and comprising a conductive metal layer and a metal oxide layer stacked on one another, wherein the metal oxide layer comprises MoxTayOz, wherein a content of tantalum is equal to or less than 2.0 at % (atomic percent) based on a total number of metal atoms.

Abstract: Techniques perform failure recovery of a storage device. The techniques involve: determining, based on failure data indicating at least one failed disk, whether the at least one failed disk comprises a system disk associated with an extent pool of the storage device, the extent pool being built based on system disks and user disks; in response to determining that the at least one failed disk comprises a system disk, rebuilding the user data of the system disk to one or more further disks associated with the extent pool; and in response to the system disk being replaced with an updated system disk, restoring the rebuilt user data from the one or more further disks to the updated system disk, an association of the system disk with the extent pool being maintained until the system disk is replaced by the updated system disk.

Abstract: A broadcast receiving apparatus may comprise: a broadcast interface for receiving a broadcast signal comprising an emergency alert message and signaling information indicating metadata for the emergency alert message; a control unit for generating an emergency alert multicast message comprising attributes of the emergency alert message on the basis of the broadcast signal; and a companion screen interface for transferring the emergency alert multicast message to at least one companion screen device in a multicast mode.

Abstract: A linear radiation detector array system that is based on a unique focusing principle reduces or eliminates the X-ray radiation damage on the electrical components of the detector system. The system includes a layer of scintillating material, a rod lens array, and an array of image sensors. The layer of scintillating material, such as Gd2O2S:Tb (GOS or GADOX), CsI(TI), CdWO4, or GAGG:Ce is placed on an image plane and is used to convert the impinging radiation energies into visible light which can be detected efficiently by the image sensor array. The rod lens array is used to transmit and focus the visible light after the radiation flux has been converted. The photon energy of the visible light is collected with a scanning image sensor array.

Abstract: A video processing method includes receiving a bitstream, and decoding, by a video decoder, the bitstream to generate a decoded frame. The decoded frame is a projection-based frame that has a 360-degree image/video content represented by triangular projection faces packed in an octahedron projection layout. An omnidirectional image/video content of a viewing sphere is mapped onto the triangular projection faces via an octahedron projection of the viewing sphere. An equator of the viewing sphere is not mapped along any side of each of the triangular projection faces.

Abstract: Embodiments of the present disclosure provide a method, device and computer program product for migrating data. The method comprises initiating a first migration job for a first client and a second migration job for a second client. The method also comprises setting a first cache file for the first client and a second cache file for the second client, and a cache file records a hash value of a migrated file of a client. Moreover, the method further comprises executing the first migration job and the second migration job in parallel, wherein the first migration job is executed using the first cache file and the second migration job is executed using the second cache file.

Abstract: The present invention discloses a zinc transporter 8 antibody chemiluminescence immunoassay kit, including a magnetic microparticle working solution coated with purified zinc transporter 8, a purified zinc transporter 8 working solution labeled with acridinium ester, a zinc transporter 8 antibody calibrator, a chemiluminescent pre-excitation solution and a chemiluminescent excitation solution. In addition, the present invention also discloses a method for preparing the zinc transporter 8 antibody chemiluminescence immunoassay kit.

Abstract: The present invention relates to the synthesis of intermediate compounds which can be used in the synthesis of mint lactone and related compounds, including 3,6-dimethylhexahydrobenzofuran-2-ones, isomers, and other derivatives.

Abstract: Yellow inkjet inks are disclosed. In an example, an inkjet ink composition comprises: at least one colorant comprising at least one yellow pigment; at least one solvent comprising at least one triol; water; and at least one binder. The binder comprises a polyurethane-based binder dispersion, which comprises water and a polyurethane. The polyurethane comprises: (A) a polyisocyanate, (B) a first polyol having a chain with two hydroxyl functional groups at one end of the chain and no hydroxyl groups at an opposed end of the chain, (C) a second polyol having a chain with two hydroxyl functional groups at both ends of the chain, (D) a carboxylic acid functional group with two hydroxyl functional groups, and (E) a sulfonate or sulfonic acid functional group having two amino functional groups.

Abstract: Described herein are methods of filling features with tungsten, and related systems and apparatus, involving inhibition of tungsten nucleation. In some embodiments, the methods involve selective inhibition along a feature profile. Methods of selectively inhibiting tungsten nucleation can include exposing the feature to ammonia vapor in a non-plasma process. Process parameters including exposure time, substrate temperature, and chamber pressure can be used to tune the inhibition profile. Also provided are methods of filling multiple adjacent lines with reduced or no line bending. The methods involve selectively inhibiting the tungsten nucleation to reduce sidewall growth during feature fill.

Abstract: Provided are a method for random access and a terminal device, which can implement a more flexible random access process. The method includes: a terminal device determining a first random access mode for random access; and the terminal device, according to the first random access mode, performing a random access process.

Abstract: A method for estimating a quality of semantic match of a first sentence to a second sentence comprises outputting a first hierarchy of representations of the first sentence at increasing degrees of semantic compression, outputting a second hierarchy of representations of the second sentence at increasing degrees of semantic compression, comparing a selected representation in the first hierarchy to each of a plurality of representations in the second hierarchy, comparing a selected representation in the second hierarchy to each of a plurality of representations in the first hierarchy, and outputting a match value indicating a quality of semantic match between the first sentence and the second sentence, the match value based at least on the comparisons.

Abstract: An antibody, or an antigen-binding fragment there, binding human ENO1 (GenBank: AAH506421.1) is provided. Methods for treating an ENO1 protein-related disease or disorder, inhibiting cancer invasion and diagnosis of cancer are also provided.

Abstract: The present disclosure relates to a method for preparing myo-inositol using myo-inositol monophosphate synthase consisting of an amino acid sequence of SEQ ID NO: 1 and/or myo-inositol monophosphate phosphatase consisting of an amino acid sequence of SEQ ID NO: 3.

Abstract: A cable supporting assembly for use in a rack system includes a connecting device, a cable supporting member, a first mechanism, and a second mechanism. The cable supporting member is movably mounted on the connecting device. The first mechanism is arranged at one of the connecting device and the cable supporting member, and the second mechanism, at the other. The first mechanism and the second mechanism can connect with each other to keep the cable supporting member at a predetermined position with respect to the connecting device. The cable supporting member can be moved to a first position or a second position with respect to the connecting device when the first mechanism and the second mechanism are not connected with each other.

Abstract: Techniques and devices for holding and releasing virtual objects on a display based on input received from one or more handheld controllers are described herein. In some instances, a handheld controller includes one or more sensors, such as proximity sensors, force sensors (e.g., force resisting sensors, etc.), accelerometers, and/or other types of sensors configured to receive input from a hand of a user gripping the handheld controller. Hardware, software, and/or firmware on the controller and/or on a device coupled to the controller (e.g., a game console, a server, etc.) may receive data from these sensors and generate a representation of a corresponding gesture on a display, such as a monitor, a virtual-reality system, and/or the like.

Abstract: Methods and apparatus for reducing energy consumed by drones during flight are disclosed. A drone includes a housing, a motor, receiver circuitry carried by the housing, and a route manager. The receiver circuitry is to receive airborne drone-generated wind data from an airborne drone located in an area within which a segment of a flight of the drone is to occur. The airborne drone-generated wind data is to be determined by an inertial measurement unit of the airborne drone. The route manager is to generate a route for the flight of the drone based on wind data, the wind data including the airborne drone-generated wind data. The route is to be followed by the drone during the flight. The route manager is to select at least one portion of the route to cause the drone to be at least partially propelled by wind to reduce energy consumed by the drone during the flight.

Abstract: The present disclosure relates to the genetically modified non-human animals that have a disruption at the endogenous CD132 gene (e.g., CD132 knockout), and methods of use thereof.