Patents by Inventor Yang Chuan

Yang Chuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11890342
    Abstract: A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: February 6, 2024
    Assignee: International Business Machines Corporation
    Inventors: Dylan J. Boday, Jeannette M. Garcia, James L. Hedrick, Nathaniel Park, Rudy J. Wojtecki, Yang Chuan, Ashlynn Lee, Zhen Chang Liang, Shaoqiong Liu, Yi Yan Yang
  • Patent number: 11045552
    Abstract: A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: June 29, 2021
    Assignee: International Business Machines Corporation
    Inventors: Dylan J. Boday, Jeannette M. Garcia, James L. Hedrick, Nathaniel H. Park, Rudy J. Wojtecki, Yang Chuan, Ashlynn Lee, Zhen Chang Liang, Shaoqiong Liu, Yi Yan Yang
  • Publication number: 20210145970
    Abstract: A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.
    Type: Application
    Filed: December 22, 2020
    Publication date: May 20, 2021
    Inventors: Dylan J. BODAY, Jeannette M. GARCIA, James L. HEDRICK, Nathaniel PARK, Rudy J. WOJTECKI, Yang CHUAN, Ashlynn LEE, Zhen Chang LIANG, Shaoqiong LIU, Yi Yan YANG
  • Publication number: 20180280515
    Abstract: A stimulus-responsive micellar carrier, methods that may be associated with making a stimulus-responsive micellar carrier, and methods that may be associated with using a stimulus-responsive micellar carrier are disclosed. The stimulus-responsive micellar carrier comprises a cargo molecule, and a linear block copolymer having a hydrophilic block connected to a hydrophobic block by a stimulus-responsive junction moiety. The micellar carrier can be supplied to a patient body for therapeutic purposes, such as the treatment of cancerous tissue. A method of preparing or obtaining a stimulus-responsive micellar carrier may include preparing a polyethylene glycol material having an acetal end group and then preparing a block copolymer by forming a reaction mixture including the polyethylene glycol material, a cyclic carbonate monomer, and a base.
    Type: Application
    Filed: April 4, 2017
    Publication date: October 4, 2018
    Inventors: Dylan J. BODAY, Jeannette M. GARCIA, James L. HEDRICK, Nathaniel H. PARK, Rudy J. WOJTECKI, Yang CHUAN, Ashlynn LEE, Zhen Chang LIANG, Shaoqiong LIU, Yi Yan YANG
  • Patent number: 9189861
    Abstract: An image processing device has an affinity calculating unit that handles each pixel in an image or each region including a plurality of pixels joined together, as a unit component, and determines a first affinity between each of the unit components and one of the unit components which is located in a periphery region of the image, a foreground region identifying unit that identifies, as a foreground region, a region made up of one or more of the unit components whose first affinities calculated by the affinity calculating unit are lower than a preset threshold, and a saliency measure output unit that determines a second affinity between each of the unit components in the image and the foreground region identified by the foreground region identifying unit, and outputs the second affinity as a saliency measure for each unit component.
    Type: Grant
    Filed: February 27, 2014
    Date of Patent: November 17, 2015
    Assignee: OMRON Corporation
    Inventors: Xiang Ruan, Lu Huchuan, Yang Chuan, Zhang Lihe
  • Publication number: 20140321748
    Abstract: An image processing device has an affinity calculating unit that handles each pixel in an image or each region including a plurality of pixels joined together, as a unit component, and determines a first affinity between each of the unit components and one of the unit components which is located in a periphery region of the image, a foreground region identifying unit that identifies, as a foreground region, a region made up of one or more of the unit components whose first affinities calculated by the affinity calculating unit are lower than a preset threshold, and a saliency measure output unit that determines a second affinity between each of the unit components in the image and the foreground region identified by the foreground region identifying unit, and outputs the second affinity as a saliency measure for each unit component.
    Type: Application
    Filed: February 27, 2014
    Publication date: October 30, 2014
    Applicant: OMRON Corporation
    Inventors: Xiang Ruan, Lu Huchuan, Yang Chuan, Zhang Lihe