Patents by Inventor Yang Ho Jo

Yang Ho Jo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutated immunoglobulin-binding protein having increased alkaline tolerance
    Patent number: 10766933
    Abstract: The present invention relates to a mutated immunoglobulin-binding protein having increased alkaline tolerance and, more specifically, to an immunoglobulin-binding protein in which, with respect to the A-domain of Staphylococcal protein A, or a functional variant thereof, an amino acid at a specific site is mutated and thereby exhibits an increased chemical stability at an alkaline pH value in comparison to a parental molecule. The present invention can provide an antibody-purifying immunoglobulin-binding protein ligand and matrix which have enhanced alkaline tolerance and accordingly enhanced stability in multiple times of alkaline cleaning.
    Type: Grant
    Filed: January 4, 2019
    Date of Patent: September 8, 2020
    Assignee: Amicogen, Inc.
    Inventors: Yong Chul Shin, Zhe Piao, Su-Lim Choi, Yang Ho Jo, So-Young Park, Dae Beom Kwon
  • Mutated Immunoglobulin-Binding Protein Having Increased Alkaline Tolerance
    Publication number: 20190202871
    Abstract: The present invention relates to a mutated immunoglobulin-binding protein having increased alkaline tolerance and, more specifically, to an immunoglobulin-binding protein in which, with respect to the A-domain of Staphylococcal protein A, or a functional variant thereof, an amino acid at a specific site is mutated and thereby exhibits an increased chemical stability at an alkaline pH value in comparison to a parental molecule. The present invention can provide an antibody-purifying immunoglobulin-binding protein ligand and matrix which have enhanced alkaline tolerance and accordingly enhanced stability in multiple times of alkaline cleaning.
    Type: Application
    Filed: January 4, 2019
    Publication date: July 4, 2019
    Inventors: Yong Chul Shin, Zhe Piao, Su-Lim Choi, Yang Ho Jo, So-Young Park, Dae Beom Kwon