Abstract: The present invention relates to a composition comprising a Salvia miltiorrhiza extract for prevention and treatment of depression in menopausal women. The Salvia miltiorrhiza extract of the present invention is characterized by regulating the release of luteinizing hormone and follicle-stimulating hormone and increasing the release of serotonin and norepinephrine to prevent, alleviate, and treat the hormonal change and depression occurring after menopause. In addition, since the raw material is highly stable, the composition comprising a danshensu-containing Salvia miltiorrhiza extract as an active ingredient retains the efficacy during long-term storage and thus can be suitable for use as an industrial substance.

Abstract: Provided is a pharmaceutical composition for preventing, alleviating or treating coronavirus infection, containing an Elaeocarpus sylvestris leaf extract as an active ingredient, and a food composition for preventing or alleviating coronavirus infection. Since the Elaeocarpus sylvestris leaf extract exhibits excellent anti-viral activity against coronavirus which is a virus causing a respiratory disease, a digestive disease, a liver disease or a brain disease in a mammal, particularly, the corona-19 virus, it may be effectively used in medicines and food for preventing, alleviating or treating a disease caused by coronavirus infection.

Abstract: The present invention relates to a composition containing PIAS3 as an active ingredient for the prevention or treatment of cancer or immune disease. More specifically, the present invention relates to a composition containing the PIAS3 gene or an expressing protein thereof as an active ingredient for the prevention or treatment of cancer or immune disease, to an immunosuppressant composition, to a method for reducing or inhibiting undifferentiated T cells into Th17 cells using the PIAS3 gene or an expressing protein thereof, and to a method for activating regulatory T cells.

Abstract: The present invention relates to a composition containing PIAS3 as an active ingredient for the prevention or treatment of cancer or immune disease. More specifically, the present invention relates to a composition containing the PIAS3 gene or an expressing protein thereof as an active ingredient for the prevention or treatment of cancer or immune disease, to an immunosuppressant composition, to a method for reducing or inhibiting undifferentiated T cells into Th17 cells using the PIAS3 gene or an expressing protein thereof, and to a method for activating regulatory T cells.