Patents by Inventor Yang Qiu

Yang Qiu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12448306
    Abstract: An anode, a flow cell including the anode, and a method for electrocatalytic treatment of bio-oil and/or wastewater are disclosed. The anode comprises RuO2 particles on a titanium support. The method includes flowing a process stream through the flow cell in the absence of added hydrogen, at a temperature of 0° C. to 50° C. and atmospheric pressure, and applying a potential across the flow cell such that the anode is positive with respect to the cathode, thereby electrocatalytically oxidizing compounds in the process stream to produce a treated process stream at the anode and generating hydrogen gas as a byproduct at the cathode.
    Type: Grant
    Filed: March 26, 2021
    Date of Patent: October 21, 2025
    Assignee: Battelle Memorial Institute
    Inventors: Juan A. Lopez-Ruiz, Jonathan D. Egbert, Charles J. Freeman, Oliver Y. Gutiérrez Tinoco, Jamelyn D. Holladay, Daniel T. Howe, Yang Qiu, Ismael A. Rodriguez Perez
  • Publication number: 20250263436
    Abstract: One of the core sequences of a polypeptide inhibitor provided by the present invention is as shown in SEQ ID NO.1, and the sequence of a polypeptide comprising a cell-penetrating peptide is as shown in SEQ ID NO.2. The polypeptide provided by the present invention uses enterovirus 2C protein multimerization as a target. Compared with other inhibitors targeting an enterovirus 2C protein, the present invention has high inhibition efficiency, good safety, and provides a new policy for enterovirus prevention and control.
    Type: Application
    Filed: March 19, 2021
    Publication date: August 21, 2025
    Applicant: WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Xi ZHOU, Yuan FANG, Yang QIU, Di WU, Muhan HUANG, Ting SHU
  • Publication number: 20250161203
    Abstract: The present invention provides devices and methods for delivering a population of cells or a therapeutic agent to a subject in need thereof.
    Type: Application
    Filed: November 26, 2024
    Publication date: May 22, 2025
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Christopher Thanos, Yang Qiu
  • Patent number: 12194138
    Abstract: The present invention provides devices and methods for delivering a population of cells or a therapeutic agent to a subject in need thereof.
    Type: Grant
    Filed: May 4, 2022
    Date of Patent: January 14, 2025
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Christopher Thanos, Yang Qiu
  • Publication number: 20240220291
    Abstract: A method for facilitating user input into a form of a graphical user interface is disclosed. In one embodiment, such a method includes receiving a form implemented on a graphical user interface. The form has multiple fields. The method automatically scans the form to determine relationships such as dependencies between the fields and automatically generates a knowledge graph that describes the fields and their relationships. The fields may be represented as nodes in the knowledge graph. The method enables a user to select a designated field in the form and display the knowledge graph to show relationships between the designated field and other fields in the form. A corresponding system and computer program product are also disclosed.
    Type: Application
    Filed: December 31, 2022
    Publication date: July 4, 2024
    Applicant: International Business Machines Corporation
    Inventors: Wei Jun Zheng, Hua Hong Wang, Yuan Jie Song, Min Huang, Qing Lu, Yang Qiu
  • Patent number: 11999806
    Abstract: Provided are a series of polypeptides with antiviral activity. The present invention provides a new strategy for preventing and controlling Enterovirus such as EV71, CVA16, CVA6, CVB3, and CVB5 viruses and provides a new theoretical basis for accelerating the research and development of a polypeptide small molecule drug against Enterovirus such as EV71, CVA16, CVA6, CVB3, and CVB5 viruses.
    Type: Grant
    Filed: January 21, 2019
    Date of Patent: June 4, 2024
    Assignees: WUHAN INSTITUTE OF VIROLOGY, CHINESE ACADEMY OF SCIENCES, FUDAN UNIVERSITY
    Inventors: Xi Zhou, Lu Lu, Yuan Fang, Shibo Jiang, Zezhong Liu, Chengfeng Qin, Yang Qiu, Jingfang Mu
  • Publication number: 20230192769
    Abstract: Provided are a series of polypeptides with antiviral activity. The present invention provides a new strategy for preventing and controlling Enterovirus such as EV71, CVA16, CVA6, CVB3, and CVB5 viruses and provides a new theoretical basis for accelerating the research and development of a polypeptide small molecule drug against Enterovirus such as EV71, CVA16, CVA6, CVB3, and CVB5 viruses.
    Type: Application
    Filed: January 21, 2019
    Publication date: June 22, 2023
    Inventors: Xi ZHOU, Lu LU, Yuan FANG, Shibo JIANG, Zezhong LIU, Chengfeng QIN, Yang QIU, Jingfang MU
  • Publication number: 20220331234
    Abstract: The present invention provides devices and methods for delivering a population of cells or a therapeutic agent to a subject in need thereof.
    Type: Application
    Filed: May 4, 2022
    Publication date: October 20, 2022
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Christopher Thanos, Yang Qiu
  • Patent number: 11398630
    Abstract: The present disclosure relates to a method of generating energy. This method involves providing a fuel cell comprising anode and cathode electrodes; a separator positioned between the anode and cathode electrodes; and anode and cathode catalysts. The anode catalyst comprises (i) a low-loading of platinum group metals (PGMs) supported on a Group 4-6 transition metal carbide (TMC) or nitride (TMN); (ii) an alloy or physical mixture comprising a Group 10 transition metal selected from Pt, Pd, and Ni and one or more of the following elements: Pt, Pd, Ni, Ir, Rh, Ru, Fe, Re, Sn, W, Mo, Ta, and Nb; or (iii) mixtures thereof. According to the method, a liquid anode fuel comprising one or more hydrazide compounds is added to the fuel cell to generate energy from the liquid anode fuel. Also disclosed is a fuel cell for generating energy from a liquid anode fuel comprising one or more hydrazide compounds.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: July 26, 2022
    Assignee: IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Inventors: Wenzhen Li, Le Xin, Joseph Watkins, Yang Qiu
  • Patent number: 11240997
    Abstract: Provided is a double-gene knockout vector system, a method for preparing porcine fibroblasts with both CD163 gene and CD13 gene being knocked-out, prepared porcine fibroblasts, and a method for preparing a gene-edited pig with both CD163 gene and CD13 gene being knocked-out. The vector system of the present disclosure comprises a CD163 gene knockout vector and a CD13 gene knockout vector. The CD163 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, with a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 1-3. The CD13 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 4-6.
    Type: Grant
    Filed: April 9, 2019
    Date of Patent: February 8, 2022
    Assignee: Shandong Landsee Genetics Co., Ltd.
    Inventors: Kui Li, Yulian Mu, Zhiguo Liu, Julang Li, Kui Xu, Yinghui Wei, Changli Ge, Xuehui Cai, Long Wang, Qimei Chen, Yang Qiu
  • Publication number: 20210300799
    Abstract: An anode, a flow cell including the anode, and a method for electrocatalytic treatment of bio-oil and/or wastewater are disclosed. The anode comprises RuO2 particles on a titanium support. The method includes flowing a process stream through the flow cell in the absence of added hydrogen, at a temperature of 0° C. to 50° C. and atmospheric pressure, and applying a potential across the flow cell such that the anode is positive with respect to the cathode, thereby electrocatalytically oxidizing compounds in the process stream to produce a treated process stream at the anode and generating hydrogen gas as a byproduct at the cathode.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Applicant: Battelle Memorial Institute
    Inventors: Juan A. Lopez-Ruiz, Jonathan D. Egbert, Charles J. Freeman, Oliver Y. Gutiérrez Tinoco, Jamelyn D. Holladay, Daniel T. Howe, Yang Qiu, Ismael A. Rodriguez Perez
  • Publication number: 20210005900
    Abstract: The present disclosure relates to a method of generating energy. This method involves providing a fuel cell comprising anode and cathode electrodes; a separator positioned between the anode and cathode electrodes; and anode and cathode catalysts. The anode catalyst comprises (i) a low-loading of platinum group metals (PGMs) supported on a Group 4-6 transition metal carbide (TMC) or nitride (TMN); (ii) an alloy or physical mixture comprising a Group 10 transition metal selected from Pt, Pd, and Ni and one or more of the following elements: Pt, Pd, Ni, Ir, Rh, Ru, Fe, Re, Sn, W, Mo, Ta, and Nb; or (iii) mixtures thereof. According to the method, a liquid anode fuel comprising one or more hydrazide compounds is added to the fuel cell to generate energy from the liquid anode fuel. Also disclosed is a fuel cell for generating energy from a liquid anode fuel comprising one or more hydrazide compounds.
    Type: Application
    Filed: March 6, 2020
    Publication date: January 7, 2021
    Inventors: Wenzhen LI, Le XIN, Joseph WATKINS, Yang QIU
  • Publication number: 20200323182
    Abstract: Provided is a double-gene knockout vector system, a method for preparing porcine fibroblasts with both CD163 gene and CD13 gene being knocked-out, prepared porcine fibroblasts, and a method for preparing a gene-edited pig with both CD163 gene and CD13 gene being knocked-out. The vector system of the present disclosure comprises a CD163 gene knockout vector and a CD13 gene knockout vector. The CD163 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, with a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 1-3. The CD13 gene knockout vector comprises a gene editing vector backbone and a DNA fragment ligated to the gene editing vector backbone, a nucleotide sequence of the DNA fragment being shown in any one of SEQ ID NOs: 4-6.
    Type: Application
    Filed: April 9, 2019
    Publication date: October 15, 2020
    Inventors: Kui Li, Yulian Mu, Zhiguo Liu, Julang Li, Kui Xu, Yinghui Wei, Changli Ge, Xuehui Cai, Long Wang, Qimei Chen, Yang Qiu
  • Patent number: 10598585
    Abstract: A method and a device for synchronous high-speed photographing of microparticle rotation in a liquid cyclone field and for determining the rotation velocity of a microparticle in a liquid cyclone field by using a combination of a synchronous high-speed photographing system and a transparent microparticle containing two centrosymmetrically arranged inner cores having the same diameter. The method comprises: using a transparent microparticle comprising two inner cores having the same diameter and arranged centrosymmetrically as a rotation test particle; acquiring synchronously two groups of two dimensional image series of microparticle motion in a liquid cyclone field using two orthogonally arranged high-speed digital cameras; and reconstructing a three dimensional motion trajectory of the microparticle from the two groups of synchronous image series, and determining a rotation velocity of the microparticle in the cyclone field at the same time.
    Type: Grant
    Filed: June 15, 2015
    Date of Patent: March 24, 2020
    Assignee: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Hualin Wang, Yuan Huang, Yang Qiu, Pengbo Fu, Yanhong Zhang, Zhishan Bai, Qiang Yang, Fengqin He
  • Patent number: 10551446
    Abstract: A magnetic sensor for superconducting quantum interference device using single operational amplifier comprising SQUID, a feedback coil, feedback resistor and an operational amplifier. The voltage signal of SQUID is delivered to one input of the operational amplifier, a bias voltage is delivered to other input of the operational amplifier, and the output of the operational amplifier connects to one end of a feedback resistor, the other end of the feedback resistor connects to a feedback coil that is coupled through mutual inductance with the SQUID so as to generate feedback magnetic flux, the output voltage of the operational amplifier drives the feedback resistance to generate current, thereby forming a flux locking loop. The present invention uses an open loop operational amplifier to implement SQUID magnetic flux locking feedback circuit which simplifies the circuit configuration, decrease the loop delay and thereby achieving higher bandwidth of the flux locking loop.
    Type: Grant
    Filed: June 25, 2015
    Date of Patent: February 4, 2020
    Assignee: SHANGHAI INSTITUTE OF MICROSYSTEM AND INFORMATION TECHNOLOGY, CHINESE ACADEMY OF SCIENCES
    Inventors: Yongliang Wang, Yi Zhang, Kai Chang, Hans-Joachim Krause, Xiaofeng Xu, Yang Qiu
  • Patent number: 10446852
    Abstract: The present invention relates to a fuel-cell system. This system includes an anode electrode; a cathode electrode; a separator positioned between the anode electrode and the cathode electrode, wherein the separator is not an ion exchange membrane; an anode catalyst; and a cathode catalyst, wherein the cathode catalyst is a non-precious metal catalyst or metal-free catalyst. The present invention also relates to a method of generating energy from crude fuel. This method involves providing a fuel-cell system and contacting the fuel-cell system with a crude fuel under conditions effective to generate energy from the crude fuel.
    Type: Grant
    Filed: March 14, 2017
    Date of Patent: October 15, 2019
    Assignee: Iowa State University Research Foundation, Inc.
    Inventors: Wenzhen Li, Neeva Benipal, Ji Qi, Yang Qiu
  • Publication number: 20180356329
    Abstract: A method and a device for synchronous high-speed photographing of microparticle rotation in a liquid cyclone field and for determining the rotation velocity of a microparticle in a liquid cyclone field by using a combination of a synchronous high-speed photographing system and a transparent microparticle containing two centrosymmetrically arranged inner cores having the same diameter. The method comprises: using a transparent microparticle comprising two inner cores having the same diameter and arranged centrosymmetrically as a rotation test particle; acquiring synchronously two groups of two dimensional image series of microparticle motion in a liquid cyclone field using two orthogonally arranged high-speed digital cameras; and reconstructing a three dimensional motion trajectory of the microparticle from the two groups of synchronous image series, and determining a rotation velocity of the microparticle in the cyclone field at the same time.
    Type: Application
    Filed: June 15, 2015
    Publication date: December 13, 2018
    Applicant: East China University of Science and Technology
    Inventors: Hualin Wang, Yuan Huang, Yang Qiu, Pengbo Fu, Yanhong Zhang, Zhishan Bai, Qiang Yang, Fengqin He
  • Patent number: 10014437
    Abstract: An optical semiconductor device comprises, on a substrate, a fin of diamond-cubic semiconductor material and, at the base of the fin, a slab of that semiconductor material, in a diamond-hexagonal structure, that extends over the full width of the fin, the slab being configured as an optically active material. This semiconductor material can contain silicon. A method for manufacturing the optical semiconductor device comprises annealing the sidewalls of the fin, thereby inducing a stress gradient along the width of the fin.
    Type: Grant
    Filed: March 7, 2017
    Date of Patent: July 3, 2018
    Assignees: IMEC VZW, Katholieke Universiteit Leuven, KU Leuven R&D
    Inventors: Hugo Bender, Yang Qiu
  • Publication number: 20170263945
    Abstract: The present invention relates to a fuel-cell system. This system includes an anode electrode; a cathode electrode; a separator positioned between the anode electrode and the cathode electrode, wherein the separator is not an ion exchange membrane; an anode catalyst; and a cathode catalyst, wherein the cathode catalyst is a non-precious metal catalyst or metal-free catalyst. The present invention also relates to a method of generating energy from crude fuel. This method involves providing a fuel-cell system and contacting the fuel-cell system with a crude fuel under conditions effective to generate energy from the crude fuel.
    Type: Application
    Filed: March 14, 2017
    Publication date: September 14, 2017
    Inventors: Wenzhen Li, Neeva Benipal, Ji Qi, Yang Qiu
  • Patent number: D1124129
    Type: Grant
    Filed: April 2, 2025
    Date of Patent: April 28, 2026
    Assignee: Changsha Yangfa E-commerce Co., Ltd
    Inventor: Yang Qiu