Patents by Inventor Yang-Sook Chun

Yang-Sook Chun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for suppressing adipocyte differentiation
    Patent number: 10106797
    Abstract: Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for inhibiting adipocyte differentiation and a method for screening an adipocyte differentiation inhibitor using PPAR-v neddylation associated with adipocyte differentiation. The inhibitor of a neddylation pathway of PPAR-v inhibits the differentiation from mesenchymal stem cells to mast cells, and thus can be effectively used to treat obesity, and particularly, can be also useful in the treatment of severe obesity which cannot be excepted to be treated by existing obesity treatment agents.
    Type: Grant
    Filed: July 18, 2014
    Date of Patent: October 23, 2018
    Assignee: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Yang-Sook Chun, Hyoung Sook Park, Jong-Wan Park
  • COMPOSITION CONTAINING PPAR-gamma NEDDYLATION INHIBITOR FOR INHIBITING ADIPOCYTE DIFFERENTIATION AND USE THEREOF
    Publication number: 20160160219
    Abstract: Provided is a method for suppressing an adipose differentiation comprising administering to a subject in need thereof a PPAR-v neddylation inhibitor for inhibiting adipocyte differentiation and a method for screening an adipocyte differentiation inhibitor using PPAR-v neddylation associated with adipocyte differentiation. The inhibitor of a neddylation pathway of PPAR-v inhibits the differentiation from mesenchymal stem cells to mast cells, and thus can be effectively used to treat obesity, and particularly, can be also useful in the treatment of severe obesity which cannot be excepted to be treated by existing obesity treatment agents.
    Type: Application
    Filed: July 18, 2014
    Publication date: June 9, 2016
    Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Yang-Sook CHUN, Hyoung Sook PARK, Jong-Wan PARK
  • Compounds, compositions and methods
    Publication number: 20050187276
    Abstract: The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF and HIF regulated genes, inhibiting angiogenesis, inducing cell cycle arrest in tumor cells, and treating cell proliferating diseases or conditions.
    Type: Application
    Filed: June 30, 2004
    Publication date: August 25, 2005
    Inventors: Jong-Wan Park, Yang-Sook Chun, Kenneth Bair, Ho Cho
  • Method for inhibiting tumor angiogenesis and tumor growth
    Publication number: 20050096370
    Abstract: The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF-1 and HIF-1-regulated genes, angiogenesis, tumor growth, or tumor progression/metastasis comprising contacting the tumor cells or tissue with a composition comprising 3-(5?-hydroxymethyl-2?-furyl)-1-benzylindazole, or a novel derivative thereof.
    Type: Application
    Filed: August 14, 2003
    Publication date: May 5, 2005
    Inventors: Jong-Wan Park, Yang-Sook Chun, Jinho Kim
  • Method for inhibiting tumor angiogenesis and tumor growth
    Publication number: 20040198798
    Abstract: The present invention provides methods and pharmaceutical compositions for inhibiting expressions of HIF-1 and HIF-1-regulated genes, angiogenesis, tumor growth, or tumor progression/metastasis comprising contacting the tumor cells or tissue with a composition comprising 3-(5′-hydroxymethyl-2′-furyl)-1-benzylindazole.
    Type: Application
    Filed: April 7, 2003
    Publication date: October 7, 2004
    Inventors: Jong-Wan Park, Yang-Sook Chun, Jinho Kim