Patents by Inventor Yang Sui Brooks

Yang Sui Brooks has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for the treatment of cancer
    Patent number: 10188747
    Abstract: The technology described herein is directed to agonists of, e.g. Esr2, Dlx5, and/or Egr3, for the inhibition of cancer cells (e.g. squamous carcinoma cancer cells) and the treatment of cancer.
    Type: Grant
    Filed: February 12, 2015
    Date of Patent: January 29, 2019
    Assignee: The General Hospital Corporation
    Inventors: Gian Paolo Dotto, Yang Sui Brooks
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
    Publication number: 20160339119
    Abstract: The technology described herein is directed to agonists of e.g. Esr2, Dlx5, and/or Egr3, for the inhibition of cancer cells (e.g. squamous carcinoma cancer cells) and the treatment of cancer.
    Type: Application
    Filed: February 12, 2015
    Publication date: November 24, 2016
    Applicant: THE GENERAL HOSPITAL CORPORATION
    Inventors: Gian Paolo DOTTO, Yang Sui BROOKS
  • GENE AMPLIFICATION OF COACTIVATOR COAA AND USES THEREOF
    Publication number: 20080241140
    Abstract: It has been discovered that amplifications in the gene coactivator activator (CoAA) blocks stem cell differentiation and induces cancer stem cells. One embodiment provides compositions and methods for treating or alleviating one or more symptoms associated with cancer due to gene amplifications in CoAA. Another embodiment provides methods and compositions for detecting cancer due to gene amplifications in CoAA. Still another embodiment provides methods for identifying compounds, antibodies and nucleic acid molecules that are useful for treating cancer due to gene amplifications in CoAA. Preferably the disclosed compositions antagonize or interfere with the CoAA amplicons and the biological activity of CoAA and or splice variants thereof.
    Type: Application
    Filed: February 12, 2008
    Publication date: October 2, 2008
    Inventors: Lan Ko, Yang Sui Brooks