Abstract: A multifunctional insulator cleaning device includes: a cleaning component, a driving assembly, an adjustment component, and a triggering component, the cleaning component including the driving assembly, and two transmission assemblies symmetrically and slidably disposed at two ends of the driving assembly; abutment assemblies symmetrically fixed to the transmission assemblies; a cleaning assembly disposed at the abutment assemblies, the cleaning assembly being detachably insertable into the transmission assemblies, the driving assembly configured to drive the two transmission assemblies to operate, the two transmission assemblies configured to drive the cleaning assembly to rotate. When the two transmission assemblies move away from each other, the cleaning assembly is detachable from the transmission assemblies and the abutment assemblies.

Abstract: This mucosal cell collection device includes an ultrasonic irradiation means, a tubular member that is provided around the ultrasonic irradiation means and has a protruding portion protruding beyond one end of the ultrasonic irradiation means, an introduction means that introduces liquid into a space formed by the ultrasonic irradiation means, the protruding portion of the tubular member, and a subject, and an extraction means that extracts cells separated from the mucosa of the subject from the space together with the liquid.

Abstract: The present disclosure provides an ergosterol-loaded brain-targeting nano-formulation, a preparation method thereof, in the nano-formulation, the active ingredient ergosterol is encapsulated in a DSPE-PEG-pinacol boronate nanomaterial. This nanomaterial possesses reactive oxygen species (ROS)-responsive properties. The ergosterol-loaded nano-formulation exhibits a regular spherical morphology, uniform particle size, good dispersibility, and good stability. The nano-formulation possesses a good capability for the targeted therapy of ischemic stroke. The nano-formulation effectively addresses problems associated with conventional drugs, such as poor targeting and low bioavailability. The nano-formulation enhances the therapeutic effect of ergosterol on ischemic stroke, can effectively ameliorate brain damage caused by ischemic stroke, and exhibits a good therapeutic effect.

Abstract: A method comprising generating, using a convolutional neural network model, one or more candidate objects based on one or more images of a scene, wherein the one or more images comprise one or more color depth images that are captured by a camera sensor; determining one or more uncertainty scores for the one or more candidate objects based on an information entropy function; and initiating, using a sparse light detection and ranging (LiDAR) sensor, scanning of one or more regions of interest (ROIs) that are determined based on the one or more uncertainty scores, wherein the scanning comprises (i) initiating capture of one or more enhancement frames for the one or more ROIs and (ii) generating one or more detected objects from the one or more ROIs based on the one or more enhancement frames.

Abstract: The invention provides a paeoniflorin crystal form A and preparation method and application thereof. The crystal form A is characterized by means of XRD, IR, DSC, TGA and the like. The powder diffraction pattern of the crystal form A obtained by using an X-ray powder diffraction method of Cu Ka has diffraction peaks at the following angles of 2?: 6.73°±0.2°, 7.94°±0.2°, 13.57°±0.2°, 15.53°±0.2°, 15.98°±0.2°, 17.16°±0.2°, 17.62°±0.2°, 20.45°±0.2°, 25.60°±0.2°. The paeoniflorin crystal form A of the present invention has low hygroscopicity and good physical stability, and is an ideal pharmaceutical crystal form.

Abstract: Systems and methods for remote human motor training. The method comprises generating visual guidance data based on first motion data received from a first client computing device, transmitting the visual guidance data to a second client computing device, receiving second motion data from the second client computing device, generating haptic guidance data based on a comparison of the second motion data with the first motion data, and transmitting the haptic guidance data to the second client computing device.

Abstract: The present disclosure provides a vinylation coupled derivative of ?-elemene, and a preparation method and use thereof in preparation of an antitumor drug. The present disclosure provides a vinylation coupled derivative of ?-elemene having a structure shown in Formula (I), a pharmaceutical composition and a hydrate including a compound shown in Formula (I), as well as an isotopic derivative, a chiral isomer, a variant, a salt, a prodrug, and a preparation of the compound shown in Formula (I). The present disclosure further provides a preparation method and use of the vinylation coupled derivative of ?-elemene, and an inhibitory activity of the derivative on proliferation of various tumor cell lines. The vinylation coupled derivative of ?-elemene is expected to be an antitumor drug candidate for treating colon cancer and lung cancer.

Abstract: Provided herein are compound-linker constructs and antibody-drug-conjugates of compounds of formula (Y-1), (Y-2), (Y-3), (A), (B), (C), I, II, III, IV or V that are useful as modulators of STING (Stimulator of Interferon Genes). Also provided are synthesis, compositions and uses of such compound-linker constructs and antibody-drug-conjugates.

Abstract: Compounds of general Formula S-1, S-2, S-3 and their pharmaceutically acceptable salts, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are synthesis, compositions, and uses of such compounds.

Abstract: Compounds of general Formula I, II, III, IV, V and their pharmaceutically acceptable salts, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are synthesis, compositions, and uses of such compounds.

Abstract: Systems and methods for remote human motor training. The method comprises generating visual guidance data based on first motion data received from a first client computing device, transmitting the visual guidance data to a second client computing device, receiving second motion data from the second client computing device, generating haptic guidance data based on a comparison of the second motion data with the first motion data, and transmitting the haptic guidance data to the second client computing device.

Abstract: A nuclear magnetic resonance (NMR) system-based substance measurement method, including: acquiring several echo signals of an NMR pulse sequence varying in echo spacing from a substance to be measured followed by processing to obtain several signals varying in transverse relaxation and diffusion attenuation; and fitting, in combination with the prior knowledge, the signals to obtain the diffusion coefficient, transverse relaxation time or/and content weight of individual components of the substance to be measured. This application further provides a substance measurement system including a console, a magnet module, and an NMR system.

Abstract: A nuclear magnetic resonance (NMR) system-based substance measurement method, including: acquiring several echo signals of an NMR pulse sequence varying in echo spacing from a substance to be measured followed by processing to obtain several signals varying in transverse relaxation and diffusion attenuation; and fitting, in combination with the prior knowledge, the signals to obtain the diffusion coefficient, transverse relaxation time or/and content weight of individual components of the substance to be measured. This application further provides a substance measurement system including a console, a magnet module, and an NMR system.

Abstract: Disclosed are stemospironine salts of Formula 1: wherein HX represents HCl, HBr, L-tartaric acid, D-tartaric acid, sulfuric acid, (+)-(1S)-10-camphorsulfonic acid, ethanesulfonic acid and ethane-1,2-disulfonic acid. This invention also provides crystalline polymorph forms of the compound of Formula 1 wherein HX is HCl, stemospironine hydrochloride. This invention also provides a new crystalline form of the compound of Formula 2, stemospironine free base: Also disclosed are compositions containing one or more compounds of Formula 1, methods for controlling cough comprising administering a therapeutically effective amount of a compound of Formula 1, and methods for preparing compounds of Formula 1. Also disclosed is a method for preparing crystalline stemospironine hydrochloride polymorph Form II from stemospironine hydrochloride polymorph Form I.

Abstract: A negative feedback closed loop circuit composed of an operational amplifier, a main switch, and a current sense resistor is applied to limit the current to a pre-defined threshold whenever there is an overload or short circuit condition is the circuit. A timing circuit composed of resistors and a capacitor is used to provide timing of turning off the circuit. The timing circuit is always charged from the same voltage and started from the same moment of main switching entering into current limit mode. The voltage reference is set by a voltage divider. The timing capacitor voltage and the voltage reference is compared in a comparator. Since both the amplifier circuit and the comparator circuit are temperature independent, the current limiting point and the time delay to turn off the switch are also both independent of temperature.

Abstract: Disclosed are stemospironine salts of Formula 1: wherein HX represents HCl, HBr, L-tartaric acid, D-tartaric acid, sulfuric acid, (+)-(1S)-10-camphorsulfonic acid, ethanesulfonic acid and ethane-1,2-disulfonic acid. This invention also provides crystalline polymorph forms of the compound of Formula 1 wherein HX is HCl, stemospironine hydrochloride. This invention also provides a new crystalline form of the compound of Formula 2, stemospironine free base: Also disclosed are compositions containing one or more compounds of Formula 1, methods for controlling cough comprising administering a therapeutically effective amount of a compound of Formula 1, and methods for preparing compounds of Formula 1. Also disclosed is a method for preparing crystalline stemospironine hydrochloride polymorph Form II from stemospironine hydrochloride polymorph Form I.

Abstract: A composite material for purifying air includes a porous foam material which is an open-cell polyurethane foam net; and a mixture sprayed on the interior and/or the surface of the porous foam material, the mixture including an absorbent material, a treating agent and an adhesive; wherein the adsorptive material is diatomite, and the treating agent is alkali solution.

Abstract: A negative feedback closed loop circuit composed of an operational amplifier, a main switch, and a current sense resistor is applied to limit the current to a pre-defined threshold whenever there is an overload or short circuit condition is the circuit. A timing circuit composed of resistors and a capacitor is used to provide timing of turning off the circuit. The timing circuit is always charged from the same voltage and started from the same moment of main switching entering into current limit mode. The voltage reference is set by a voltage divider. The timing capacitor voltage and the voltage reference is compared in a comparator. Since both the amplifier circuit and the comparator circuit are temperature independent, the current limiting point and the time delay to turn off the switch are also both independent of temperature.

Abstract: A composite material for purifying air includes a porous foam material which is an open-cell polyurethane foam net; and a mixture sprayed on the interior and/or the surface of the porous foam material, the mixture including an absorbent material, a treating agent and an adhesive; wherein the adsorptive material is diatomite, and the treating agent is alkali solution.

Abstract: A direct current electrical power system having AC grid power attached to the bus through AC/DC converter, PV panel attached to the bus through DC/DC pre-conditioner, a first direct current load attached directly to the bus, and a second direct current load attached to the bus through a DC/DC converter. The function of the AC grid and AC/DC converter is to create and regulate the DC bus voltage. The function of the PV power is to provide as much power as required to the DC loads. Since the conversion efficiency of the DC/DC pre-conditioner is much higher than that of the AC/DC converter, the conversion loss is greatly reduced if the load is mainly powered from PV instead of AC grid. In addition, a battery can be attached to the bus through a battery charger/controller, which is a bi-directional DC/DC converter.