Abstract: Disclosed is a system for predicting programmed ribosomal frameshift sites in genome sequences, in which programmed frameshifts, which are difficult to detect because of their variation with gene types, are classified into ?1 frameshifts and +1 frameshifts as basic frameshift models, each consisting of four types of modules, and the modules are combined in various ways, whereby the system can predict frameshifts of various user-defined modules and computationally detect frameshifts at high efficiency. Also, the present invention provides related web service which is accessible regardless of the operating system of the user's computer. Request messages for frameshifts and response messages to the search results of frameshifts are sent and received in XML format, so that they can be flexibly applied to programs using various languages.

Abstract: Disclosed is a method for partitioned layout of protein interaction networks into a three-dimensional graph, comprising the steps of grouping nodes into group 1, group 2 and group 3 based on their interaction properties; computing shortest paths between nodes of each group, between nodes of the group 1 and nodes of the group 2, between nodes of the group 1 and nodes of the group 3, and between nodes of the group 2 and nodes of the group 3; and layout drawing by positioning nodes of the group 3 in the center of a sphere, nodes of the group 2 in the outer region of the group 3, and nodes of the group 1 in the outer region of the groups 2 and 3, by spring-force layout algorithm. The present invention is advantageous in terms of a clear and aesthetically pleasing drawing and being much faster than other forced-directed layouts.