Abstract: A preparation method of a cross-linked sodium hyaluronate gel is disclosed, which including: preparing an alkaline aqueous solution of hyaluronic acid: formulating a sodium hyaluronate alkali liquor with the concentration of 10-30% g/ml; and carrying out a cross-linking reaction: the cross-linking agent used in the cross-linking reaction being divinyl sulfone or 1,4-butanediol diglycidyl ether, the cross-linking reaction being carried out in an alkaline aqueous solution of hyaluronic acid, the reaction temperature of the cross-linking reaction being 20-40° C., the time of the cross-linking reaction being 4-8 h, and the like. The method of this invention has many advantages, such as easily available raw materials, mild reaction conditions, high cross-linking efficiency, simple process and post-treatment, and easy operation.

Abstract: A preparation method of a cross-linked sodium hyaluronate gel is disclosed, which including: preparing an alkaline aqueous solution of hyaluronic acid: formulating a sodium hyaluronate alkali liquor with the concentration of 10-30% g/ml; and carrying out a cross-linking reaction: the cross-linking agent used in the cross-linking reaction being divinyl sulfone or 1,4-butanediol diglycidyl ether, the cross-linking reaction being carried out in an alkaline aqueous solution of hyaluronic acid, the reaction temperature of the cross-linking reaction being 20-40° C., the time of the cross-linking reaction being 4-8 h, and the like. The method of this invention has many advantages, such as easily available raw materials, mild reaction conditions, high cross-linking efficiency, simple process and post-treatment, and easy operation.

Abstract: A method of preparing an oxidized starch haemostatic material, including adding a starch raw material to an external circulation pulsatile reactor; switching on a pump to allow inflow of dry air for drying the raw material; switching on a heat exchanger; vacuumizing the reactor; opening a nitrogen dioxide pipeline and a dry air pipeline; pumping in a mixed gas; controlling temperature at 0-120° C. by the heat exchanger; wherein nitrogen dioxide is contacted with the raw material to trigger a selective oxidation reaction and is continuously recycled; an airflow circulation switch is switched on and off at a pulsating ratio of 1:1-10 to carry out airflow pulsation; stopping inflow of nitrogen dioxide and continuing airflow circulation for 5-30 minutes; after completion of the reaction, adjusting to room temperature; vacuumizing the reactor and treating exhaust gas; allowing nitrogen gas to flow in for rinsing the replaced reactor until completion.

Abstract: A method of preparing an oxidized starch haemostatic material, including adding a starch raw material to an external circulation pulsatile reactor; switching on a pump to allow inflow of dry air for drying the raw material; switching on a heat exchanger; vacuumizing the reactor; opening a nitrogen dioxide pipeline and a dry air pipeline; pumping in a mixed gas; controlling temperature at 0-120° C. by the heat exchanger; wherein nitrogen dioxide is contacted with the raw material to trigger a selective oxidation reaction and is continuously recycled; an airflow circulation switch is switched on and off at a pulsating ratio of 1:1-10 to carry out airflow pulsation; stopping inflow of nitrogen dioxide and continuing airflow circulation for 5-30 minutes; after completion of the reaction, adjusting to room temperature; vacuumizing the reactor and treating exhaust gas; allowing nitrogen gas to flow in for rinsing the replaced reactor until completion.

Abstract: Disclosed is a method for preparing an oxidized cellulose hemostatic product, including using a sodium hydroxide solution with the concentration of 1 to 5% to pre-process a cellulose product; after removing lignins or impurities on the fiber surface, using an alkaline solution to activate the fiber surface further; after the activating treatment, using demin-water for washing until it is neutral and drying the obtained cellulose product in air to obtain a raw material; using a sodium hydroxide solution with the concentration of 5 to 20% as a solvent; adding the cellulose product, carbamide and ZnO that are 3 to 10%, 2% and 2% of the sodium hydroxide solution respectively.

Abstract: Disclosed is a method for preparing an oxidized cellulose hemostatic product, including using a sodium hydroxide solution with the concentration of 1 to 5% to pre-process a cellulose product; after removing lignins or impurities on the fiber surface, using an alkaline solution to activate the fiber surface further; after the activating treatment, using demin-water for washing until it is neutral and drying the obtained cellulose product in air to obtain a raw material; using a sodium hydroxide solution with the concentration of 5 to 20% as a solvent; adding the cellulose product, carbamide and ZnO that are 3 to 10%, 2% and 2% of the sodium hydroxide solution respectively.

Abstract: Disclosed are an apparatus and a method for preparing hemostatic gauze with high stability and absorptivity. The apparatus includes a tank body, a tank cover matching the tank body, stainless steel plates within the tank body, an ultrasonic generator under the tank body, a feed pipe and a liquid outlet, where the tank cover is arranged with an air inlet and an air outlet, and the feed pipe, the air inlet, the air outlet and the liquid outlet are all equipped with a valve respectively.