Patents by Inventor Yangjian LIU

Yangjian LIU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXTRAHEPATIC TARGETED CATIONIC LIPID COMPOUND WITH HIGH EFFICIENCY AND LOW TOXICITY AND ITS COMPOSITION
    Publication number: 20250109092
    Abstract: Provided in the present disclosure is a compound of formula (I), or an N-oxide, solvate, pharmaceutically acceptable salt or stereoisomer thereof, which is an extrahepatic targeted cationic lipid compound with high efficiency and low toxicity. Further provided are a composition containing the aforementioned compound, and the use thereof in the delivery of a therapeutic or prophylactic agent.
    Type: Application
    Filed: April 10, 2023
    Publication date: April 3, 2025
    Inventors: Gengshen SONG, Honglei ZHANG, Xichao CHEN, Huanyu WANG, Dawei HUANG, Xiaowen YU, Yangjian LIU, Yuqing LI, Rucan YAN, Lianyong QIAO, Xiaojuan LI, Xiaoling CHEN, Zhenlong SUN, Shuai WANG, Kai DONG, Jinyu ZHANG
  • Pyrrolopyrimidine comprising cyclopentyl substituent
    Patent number: 10617692
    Abstract: A pyrrolopyrimidine comprising a cyclopentyi substituent. The present invention specifically relates to a compound represented by formula. A and a stereoisomer and pharmaceutically acceptable salt thereof. The invention further relates to a method for manufacturing the pyrrolopyrimidine comprising the cyclopentyl substituent represented by formula A, a pharmaceutical composition, and an application of the compound in treating a disease induced by Janus kinase.
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: April 14, 2020
    Assignees: CENTAURUS BIOPHARMA CO., CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.
    Inventors: Li Zhu, Yangjian Liu, Chuanyu Zhang, He Wang, Hong Luo, Yinghui Sun, Yongxin Han
  • PYRROLOPYRIMIDINE COMPRISING CYCLOPENTYL SUBSTITUENT
    Publication number: 20190183899
    Abstract: A pyrrolopyrimidine comprising a cyclopentyi substituent. The present invention specifically relates to a compound represented by formula. A and a stereoisomer and pharmaceutically acceptable salt thereof. The invention further relates to a method for manufacturing the pyrrolopyrimidine comprising the cyclopentyl substituent represented by formula A, a pharmaceutical composition, and an application of the compound in treating a disease induced by Janus kinase.
    Type: Application
    Filed: June 15, 2017
    Publication date: June 20, 2019
    Applicants: CENTAURUS BIOPHARMA CO., LTD., CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD., LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.
    Inventors: Li ZHU, Yangjian LIU, Chuanyu ZHANG, He WANG, Hong LUO, Yinghui SUN, Yongxin HAN