Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: The application relates to a raw material mixing apparatus, including mixing drums and a feed pipe, each of the two mixing drums is provided with a feed port and a discharge port, the feed ports of the two mixing drums are both communicated with the feed pipe, and a switching valve is arranged on the feed pipe; a first rotating disc and a second rotating disc are rotatably connected at two ends of the mixing drum respectively, and a stirring assembly is connected between the first rotating disc and the second rotating disc in the axial direction of the mixing drum; the stirring assembly includes a central stirring element and a plurality of non-central stirring elements radially arranged between inner side walls of the mixing drums and outer side walls of the central stirring element.

Abstract: A homogenization apparatus for pepper raw materials, including a base, and an annular storage tank and a stirring barrel fixed to the base. The stirring barrel is positioned under the storage tank, the bottom center of the stirring barrel is fixedly connected to a stationary shaft, the stirring barrel is rotationally drivable to rotate together with the stationary shaft about the axis of the stationary shaft, the stationary shaft extends upward into the storage tank, a sleeve is provided on an outer side of the stationary shaft, the sleeve is rotatably connected to the stationary shaft, so that the stirring barrel rotates relative to the storage tank; a portion of the sleeve accommodated in the stirring barrel is fixedly connected with a stirring part, an upper end of the stationary shaft is fixedly connected with a connecting plate.

Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.

Abstract: An imaging marker comprised of glass and iron-containing aluminum microspheres in a gel matrix which shows uniformly good contrast with MR, US and X-Ray imaging. The marker is small and can be easily introduced into tissue through a 12-gauge biopsy needle. The concentration of glass microspheres and the size dictate the contrast for US imaging. The contrast seen in MRI resulting from susceptibility losses is dictated by the number of iron-containing aluminum microspheres; while the artifact of the marker also depends on its shape, orientation and echo time. By optimizing the size, iron concentration and gel binding, an implantable tissue marker is created which is clearly visible with all three imaging modalities.