Abstract: Disclosed is a steel for an alloy structure, the chemical elements of the steel being, in percentage by mass: 0.35-0.45% of C, 0.27-0.35% of Si, 0.6-0.8% of Mn, 0.015-0.05% of Al, 0.06-0.1% of V, 0.2-1.0% of Zr, 0.001-0.005% of Mg, 0.025% or less of P, 0.015% or less of S, 0.005% or less of N, 0.001% or less of 0, the balance being Fe and other inevitable impurities. In addition, also disclosed is a manufacturing method for the steel for an alloy structure, the method comprising steps of: (1) smelting, refining, and casting; (2) blooming and cogging; (3) secondary hot rolling to form a product; and (4) heat treatment including quenching and tempering. The steel for an alloy structure is designed by adding trace alloy elements, the steel for an alloy structure is further strengthened and toughened, and the manufacturing cost is low.