Patents by Inventor Yangshen Chen

Yangshen Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11759677
    Abstract: A respiratory training device providing both inspiratory and expiratory functional evaluation and training, as well as independent regulation of both the inspiratory and expiratory airway resistance levels used during training. The respiratory training device also includes data acquisition, recording, storage, retrieval and display functions for airway pressure monitoring data to provide functional evaluation, physiological monitoring, and diagnostic features. The respiratory training device allows the user to easily develop and follow precise and advanced training protocols, and utilize the respiratory device in both the clinical and home setting.
    Type: Grant
    Filed: February 14, 2019
    Date of Patent: September 19, 2023
    Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Thomas J. Roussel, Susan J. Harkema, Alexander V. Ovechkin, Yangshen Chen, Kevin Tran, Edward Hoyt Brown, Jr.
  • Publication number: 20210228885
    Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.
    Type: Application
    Filed: April 14, 2021
    Publication date: July 29, 2021
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
  • Patent number: 11007368
    Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: May 18, 2021
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
  • Publication number: 20210001169
    Abstract: A respiratory training device providing both inspiratory and expiratory functional evaluation and training, as well as independent regulation of both the inspiratory and expiratory airway resistance levels used during training. The respiratory training device also includes data acquisition, recording, storage, retrieval and display functions for airway pressure monitoring data to provide functional evaluation, physiological monitoring, and diagnostic features. The respiratory training device allows the user to easily develop and follow precise and advanced training protocols, and utilize the respiratory device in both the clinical and home setting.
    Type: Application
    Filed: February 14, 2019
    Publication date: January 7, 2021
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: THOMAS J. ROUSSEL, SUSAN J. HARKEMA, ALEXANDER V. OVECHKIN, YANGSHEN CHEN, KEVIN TRAN, EDWARD HOYT BROWN
  • Patent number: 10688302
    Abstract: Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: June 23, 2020
    Assignee: University of Louisville Research Foundation, Inc.
    Inventors: Susan J. Harkema, Yangshen Chen, Manikandan Ravi, Claudia Angeli, Charles Hubscher
  • Publication number: 20180236240
    Abstract: Disclosed herein are devices and methods used with neurostimulation therapy for spinal cord injury. More particularly, embodiments of the present invention relate to a sync pulse detector and methods for synchronizing signals from an implanted neurostimulator with measured physiological responses and other data.
    Type: Application
    Filed: August 18, 2016
    Publication date: August 23, 2018
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Susan J. Harkema, Yangshen Chen, Douglas J. Jackson, Manikandan Ravi, Claudia Angeli
  • Publication number: 20180236241
    Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.
    Type: Application
    Filed: August 18, 2016
    Publication date: August 23, 2018
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
  • Publication number: 20180229036
    Abstract: Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction.
    Type: Application
    Filed: August 18, 2016
    Publication date: August 16, 2018
    Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.
    Inventors: Susan J. Harkema, Yangshen Chen, Manikandan Ravi, Claudia Angeli, Charles Hubscher
  • Patent number: 9409023
    Abstract: Described are devices including stimulation assemblies connectable to a plurality of electrodes. The plurality of electrodes can be configured to connect to a spinal cord at a location below a lesion of the spinal cord. The stimulation assembly can be configured to deliver stimulation to selected ones of the plurality of electrodes when the stimulation assembly is connected to the plurality of electrodes when located below the lesion of the spinal cord. Methods of using the devices are also described.
    Type: Grant
    Filed: March 26, 2012
    Date of Patent: August 9, 2016
    Assignees: California Institute of Technology, University of Louisville Research Foundation, Inc., The Regents of the University of California
    Inventors: Joel W. Burdick, Yu-Chong Tai, John F. Naber, Robert S. Keynton, Victor Reggie Edgerton, Roland R. Roy, Yury Gerasimenko, Susan J. Harkema, Jonathan Hodes, Claudia A. Angeli, Mandheerej S. Nandra, Thomas Anthony Desautels, Steven L. Upchurch, Douglas J. Jackson, Nicholas A. Terrafranca, Yangshen Chen