Patents by Inventor Yangshen Chen
Yangshen Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11759677Abstract: A respiratory training device providing both inspiratory and expiratory functional evaluation and training, as well as independent regulation of both the inspiratory and expiratory airway resistance levels used during training. The respiratory training device also includes data acquisition, recording, storage, retrieval and display functions for airway pressure monitoring data to provide functional evaluation, physiological monitoring, and diagnostic features. The respiratory training device allows the user to easily develop and follow precise and advanced training protocols, and utilize the respiratory device in both the clinical and home setting.Type: GrantFiled: February 14, 2019Date of Patent: September 19, 2023Assignee: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Thomas J. Roussel, Susan J. Harkema, Alexander V. Ovechkin, Yangshen Chen, Kevin Tran, Edward Hoyt Brown, Jr.
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Publication number: 20210228885Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.Type: ApplicationFiled: April 14, 2021Publication date: July 29, 2021Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
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Patent number: 11007368Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.Type: GrantFiled: August 18, 2016Date of Patent: May 18, 2021Assignee: University of Louisville Research Foundation, Inc.Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
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Publication number: 20210001169Abstract: A respiratory training device providing both inspiratory and expiratory functional evaluation and training, as well as independent regulation of both the inspiratory and expiratory airway resistance levels used during training. The respiratory training device also includes data acquisition, recording, storage, retrieval and display functions for airway pressure monitoring data to provide functional evaluation, physiological monitoring, and diagnostic features. The respiratory training device allows the user to easily develop and follow precise and advanced training protocols, and utilize the respiratory device in both the clinical and home setting.Type: ApplicationFiled: February 14, 2019Publication date: January 7, 2021Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: THOMAS J. ROUSSEL, SUSAN J. HARKEMA, ALEXANDER V. OVECHKIN, YANGSHEN CHEN, KEVIN TRAN, EDWARD HOYT BROWN
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Patent number: 10688302Abstract: Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction.Type: GrantFiled: August 18, 2016Date of Patent: June 23, 2020Assignee: University of Louisville Research Foundation, Inc.Inventors: Susan J. Harkema, Yangshen Chen, Manikandan Ravi, Claudia Angeli, Charles Hubscher
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Publication number: 20180236240Abstract: Disclosed herein are devices and methods used with neurostimulation therapy for spinal cord injury. More particularly, embodiments of the present invention relate to a sync pulse detector and methods for synchronizing signals from an implanted neurostimulator with measured physiological responses and other data.Type: ApplicationFiled: August 18, 2016Publication date: August 23, 2018Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Susan J. Harkema, Yangshen Chen, Douglas J. Jackson, Manikandan Ravi, Claudia Angeli
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Publication number: 20180236241Abstract: Disclosed herein are methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for neurostimulation therapy for spinal cord injury. More particularly, the present invention relates to methods for providing multiple independent, simultaneous waveforms in neurostimulation therapy while minimizing or substantially eliminating undesirable interactions between the waveforms.Type: ApplicationFiled: August 18, 2016Publication date: August 23, 2018Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Susan J. Harkema, Yangshen Chen, Robert S. Keynton, Douglas J. Jackson, John Naber, Thomas Roussel, Manikandan Ravi
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Publication number: 20180229036Abstract: Embodiments of the present invention relate to methods for applying epidural electrical stimulation to improve motor function or physiological responses in paralyzed individuals. More particularly, the present invention relates to methods for creating and applying specific configurations of epidural stimulation to assist or cause a patient to perform a complex motor function or to mitigate one or more secondary consequences of paralysis including, but not limited to, cardiovascular, respiratory, bladder, temperature and sexual dysfunction.Type: ApplicationFiled: August 18, 2016Publication date: August 16, 2018Applicant: UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC.Inventors: Susan J. Harkema, Yangshen Chen, Manikandan Ravi, Claudia Angeli, Charles Hubscher
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Patent number: 9409023Abstract: Described are devices including stimulation assemblies connectable to a plurality of electrodes. The plurality of electrodes can be configured to connect to a spinal cord at a location below a lesion of the spinal cord. The stimulation assembly can be configured to deliver stimulation to selected ones of the plurality of electrodes when the stimulation assembly is connected to the plurality of electrodes when located below the lesion of the spinal cord. Methods of using the devices are also described.Type: GrantFiled: March 26, 2012Date of Patent: August 9, 2016Assignees: California Institute of Technology, University of Louisville Research Foundation, Inc., The Regents of the University of CaliforniaInventors: Joel W. Burdick, Yu-Chong Tai, John F. Naber, Robert S. Keynton, Victor Reggie Edgerton, Roland R. Roy, Yury Gerasimenko, Susan J. Harkema, Jonathan Hodes, Claudia A. Angeli, Mandheerej S. Nandra, Thomas Anthony Desautels, Steven L. Upchurch, Douglas J. Jackson, Nicholas A. Terrafranca, Yangshen Chen